DE2532568C3 - Aclacinomycin A und B, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen - Google Patents
Aclacinomycin A und B, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische ZubereitungenInfo
- Publication number
- DE2532568C3 DE2532568C3 DE2532568A DE2532568A DE2532568C3 DE 2532568 C3 DE2532568 C3 DE 2532568C3 DE 2532568 A DE2532568 A DE 2532568A DE 2532568 A DE2532568 A DE 2532568A DE 2532568 C3 DE2532568 C3 DE 2532568C3
- Authority
- DE
- Germany
- Prior art keywords
- aclacinomycin
- medium
- brown
- growth
- methanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49086390A JPS5134915B2 (US20090163788A1-20090625-C00002.png) | 1974-07-27 | 1974-07-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2532568A1 DE2532568A1 (de) | 1976-02-12 |
| DE2532568B2 DE2532568B2 (de) | 1979-02-22 |
| DE2532568C3 true DE2532568C3 (de) | 1979-10-11 |
Family
ID=13885534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2532568A Expired DE2532568C3 (de) | 1974-07-27 | 1975-07-21 | Aclacinomycin A und B, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
Country Status (18)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4204038A (en) * | 1976-04-07 | 1980-05-20 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Process for preparing antibiotics MA 144-M1 and MA 144-M2 |
| JPS52136159A (en) * | 1976-04-07 | 1977-11-14 | Microbial Chem Res Found | Anti/malignanttumor containing the same as active ingredients |
| US4039736A (en) * | 1976-04-15 | 1977-08-02 | Bristol-Myers Company | Antibiotic compounds marcellomycin and musettamycin |
| JPS5323961A (en) * | 1976-08-16 | 1978-03-06 | Microbial Chem Res Found | Antitumors |
| US4192915A (en) * | 1976-08-16 | 1980-03-11 | Bristol-Myers Company | Anthracycline glycosides from streptomyces |
| NL176004C (nl) * | 1976-10-05 | 1985-02-01 | Microbial Chem Res Found | Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden. |
| US4209588A (en) * | 1976-10-05 | 1980-06-24 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Process for producing new antitumor anthracycline antibiotics |
| EP0003664B1 (en) * | 1978-02-08 | 1982-02-17 | Imperial Chemical Industries Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
| JPS5650105Y2 (US20090163788A1-20090625-C00002.png) * | 1978-03-01 | 1981-11-24 | ||
| ZA802929B (en) * | 1979-05-22 | 1981-05-27 | Hoffmann La Roche | Novel tetracyclic compounds and process for the preparation thereof |
| JPS6023679B2 (ja) * | 1979-07-13 | 1985-06-08 | メルシャン株式会社 | ロドマイシン群抗生物質とその製造法 |
| DE3071391D1 (en) * | 1979-09-07 | 1986-03-13 | Sanraku Ocean Co | 2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same |
| JPS57163393A (en) * | 1981-03-27 | 1982-10-07 | Microbial Chem Res Found | Novel anthracyclin derivative and its preparation |
| JPS5874694A (ja) * | 1981-10-29 | 1983-05-06 | Sanraku Inc | アントラサイクリン誘導体 |
| US4405713A (en) * | 1981-12-28 | 1983-09-20 | Hoffmann-La Roche Inc. | Process for the preparation of optically active anthracycline glycosides A and B |
| US4472571A (en) * | 1981-12-28 | 1984-09-18 | Hoffmann-La Roche Inc. | Optically active anthracycline glycosides A and B |
| IT1155446B (it) * | 1982-12-23 | 1987-01-28 | Erba Farmitalia | Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine |
| JPS6028916A (ja) * | 1983-07-13 | 1985-02-14 | Yamanouchi Pharmaceut Co Ltd | アクラルビシンまたはその塩酸塩の油性組成物 |
| US4863739A (en) * | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
| EP0396626A1 (en) * | 1988-01-19 | 1990-11-14 | Board Of Regents, The University Of Texas System | Glycosides, liposomal compositions thereof, and methods for their use |
| US4977084A (en) * | 1989-02-16 | 1990-12-11 | Board Of Trustees Operating Michigan State University | Production, isolation, and identification of novel antifungal compounds |
| US5013549A (en) * | 1989-02-16 | 1991-05-07 | Board Of Trustees Operating Michigan State University | Production, isolation, and identification of novel antifungal compounds |
| US5066585A (en) * | 1990-07-09 | 1991-11-19 | Board Of Trustees Operating Michigan State University | Method of inhibiting fungus using novel antifungal compounds |
| KR970000591B1 (ko) * | 1993-09-03 | 1997-01-14 | 동국제약 주식회사 | 신균주 스트렙토마이세스 라벤도폴리아 DKRS 및 이를 이용한 아클라시노마이신 A, B, Y 및 아글리콘(Aglycone)의 제조방법 |
| US20050208037A1 (en) * | 2003-10-21 | 2005-09-22 | Board Of Regents, The University Of Texas System | Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis |
| JP2015531356A (ja) | 2012-09-28 | 2015-11-02 | ハンジョウ ベンシェン ファーマシューティカル シーオー．， エルティーディー．Ｈａｎｇｚｈｏｕ Ｂｅｎｓｈｅｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． | 腫瘍治療のための薬剤組成物及びその適用 |
| CN111378008B (zh) * | 2020-03-02 | 2022-04-12 | 中国科学院南海海洋研究所 | 脂肽类化合物Totopotensamides及其制备方法和应用 |
-
1974
- 1974-07-27 JP JP49086390A patent/JPS5134915B2/ja not_active Expired
-
1975
- 1975-07-07 GB GB28465/75A patent/GB1491266A/en not_active Expired
- 1975-07-11 DK DK317075AA patent/DK141761B/da not_active IP Right Cessation
- 1975-07-15 ZA ZA00754555A patent/ZA754555B/xx unknown
- 1975-07-16 FR FR7522258A patent/FR2279413A1/fr active Granted
- 1975-07-16 US US05/596,682 patent/US3988315A/en not_active Expired - Lifetime
- 1975-07-21 DE DE2532568A patent/DE2532568C3/de not_active Expired
- 1975-07-23 IE IE1654/75A patent/IE42751B1/en unknown
- 1975-07-24 ES ES439747A patent/ES439747A1/es not_active Expired
- 1975-07-24 SE SE7508450A patent/SE434648B/xx not_active IP Right Cessation
- 1975-07-24 YU YU1884/75A patent/YU37188B/xx unknown
- 1975-07-25 CA CA232,210A patent/CA1055866A/en not_active Expired
- 1975-07-25 NO NO752639A patent/NO144064C/no unknown
- 1975-07-25 FI FI752142A patent/FI54496C/fi not_active IP Right Cessation
- 1975-07-25 NL NLAANVRAGE7508878,A patent/NL170754C/xx not_active IP Right Cessation
- 1975-07-25 HU HU75ZA00000385A patent/HU172209B/hu unknown
- 1975-07-25 BE BE158601A patent/BE831726A/xx not_active IP Right Cessation
- 1975-07-25 LU LU73063A patent/LU73063A1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2532568C3 (de) | Aclacinomycin A und B, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen | |
| DE1770204B1 (de) | Adriamycin und dessen Salze mit pharmakologisch vertraeglichen anorganischen und organischen Saeuren sowie diese enthaltende therapeutische Zusammensetzungen | |
| DE2743654C3 (US20090163788A1-20090625-C00002.png) | ||
| DE3836675A1 (de) | Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung | |
| CH630957A5 (de) | Verfahren zur herstellung von neuen antibiotischen verbindungen auf basis eines bohemsaeurekomplexes. | |
| DE2715255C3 (de) | Anthracyclinglykoside MA 144-M, und MA 144-M2 und deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen | |
| DE2904186C2 (de) | Anthracyclin-Glykoside, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen | |
| DE2724441C2 (de) | Als Baumycine bezeichnete Anthracyclinglycoside, Verfahren zu ihrer Herstellung und Arzneimittel | |
| DE2167325C2 (de) | Antibiotikum A-201B und Verfahren zu seiner Herstellung | |
| CH630958A5 (de) | Verfahren zur herstellung von rhodirubin a und rhodirubin b. | |
| DE2638766C2 (de) | Antibiotika,Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel | |
| DE2004686A1 (de) | Antibiotica und Verfahren zu ihrer Herstellung | |
| EP0236894B1 (de) | Efomycin G, seine Herstellung und seine Verwendung als Leistungsförderer bei Tieren | |
| DE2928373C2 (de) | Antibiotika KA-7038I bis KA-7038VII, deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende antibiotische Mittel | |
| DE2839668A1 (de) | Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung | |
| DE3012014A1 (de) | Istamycine und verfahren zur herstellung derselben | |
| DE2738656C2 (US20090163788A1-20090625-C00002.png) | ||
| DE2641908A1 (de) | Antibiotisch wirksame substanzen, mimosamycin und chlorocarcin a, b und c und verfahren zu ihrer herstellung | |
| DE2039990C2 (de) | Neue Antibiotika B-5050 A bis F (Maridomycin I bis VI), Verfahren zu ihrer Herstellung und ihre pharmazeutische Zubereitung | |
| CH637137A5 (en) | Antibiotic and process for its preparation | |
| AT220290B (de) | Verfahren zur Herstellung eines neuen Antibiotikums | |
| DE2944143C2 (de) | Antibiotikum SF-2052, Verfahren zu dessen Herstellung und das Antibiotikum SF-2052 enthaltende antibakterielle Mittel | |
| DE2760203C2 (de) | Antibiotisch wirksames Oligosaccharid, Verfahren zu seiner Herstellung sowie dieses enthaltendes Arzneimittel | |
| AT249265B (de) | Verfahren zur Gewinnung des neuen Antibiotikums Danomycin | |
| CH655109A5 (de) | Physiologisch aktive substanzen ss 12538, verfahren zu deren herstellung und neuer, diese substanzen produzierender mikroorganismus. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) |