DE2529326B2 - Verfahren zur Herstellung von mit einem Film aus wasserlöslichem Celluloseäther beschichteten Formkörpern - Google Patents
Verfahren zur Herstellung von mit einem Film aus wasserlöslichem Celluloseäther beschichteten FormkörpernInfo
- Publication number
- DE2529326B2 DE2529326B2 DE752529326A DE2529326A DE2529326B2 DE 2529326 B2 DE2529326 B2 DE 2529326B2 DE 752529326 A DE752529326 A DE 752529326A DE 2529326 A DE2529326 A DE 2529326A DE 2529326 B2 DE2529326 B2 DE 2529326B2
- Authority
- DE
- Germany
- Prior art keywords
- water
- cellulose
- solution
- suspension
- molded articles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims description 16
- 229920003086 cellulose ether Polymers 0.000 title claims description 11
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000011248 coating agent Substances 0.000 claims description 7
- 238000000576 coating method Methods 0.000 claims description 7
- 239000003086 colorant Substances 0.000 claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 4
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 3
- 229920000609 methyl cellulose Polymers 0.000 claims description 3
- 239000001923 methylcellulose Substances 0.000 claims description 3
- 235000010981 methylcellulose Nutrition 0.000 claims description 3
- 239000004014 plasticizer Substances 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 239000008188 pellet Substances 0.000 claims description 2
- -1 phthalic acid ester Chemical class 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 239000000725 suspension Substances 0.000 claims 7
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 claims 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 2
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 2
- 229930006000 Sucrose Natural products 0.000 claims 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 2
- 229920000053 polysorbate 80 Polymers 0.000 claims 2
- 239000000600 sorbitol Substances 0.000 claims 2
- 229960004793 sucrose Drugs 0.000 claims 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims 2
- 235000013681 dietary sucrose Nutrition 0.000 claims 1
- 239000001087 glyceryl triacetate Substances 0.000 claims 1
- 235000013773 glyceryl triacetate Nutrition 0.000 claims 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-N o-dicarboxybenzene Natural products OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 229960002622 triacetin Drugs 0.000 claims 1
- 239000003826 tablet Substances 0.000 description 15
- 239000000243 solution Substances 0.000 description 6
- 239000002552 dosage form Substances 0.000 description 4
- 239000006185 dispersion Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3399074 | 1974-08-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2529326A1 DE2529326A1 (de) | 1976-02-12 |
| DE2529326B2 true DE2529326B2 (de) | 1979-03-08 |
Family
ID=10359978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE752529326A Withdrawn DE2529326B2 (de) | 1974-08-01 | 1975-07-01 | Verfahren zur Herstellung von mit einem Film aus wasserlöslichem Celluloseäther beschichteten Formkörpern |
Country Status (7)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5129220A (en) * | 1974-08-08 | 1976-03-12 | Shinetsu Chemical Co | Hifukuyakuzaino seizohoho |
| JPS5624648B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-06-24 | 1981-06-08 | ||
| JPS52151717A (en) * | 1976-06-09 | 1977-12-16 | Shionogi & Co Ltd | Sugar coating on solid preparations |
| JPS5598120A (en) * | 1979-01-16 | 1980-07-25 | Shin Etsu Chem Co Ltd | Preparation of drug having enteric coating |
| US4543370A (en) | 1979-11-29 | 1985-09-24 | Colorcon, Inc. | Dry edible film coating composition, method and coating form |
| CH666405A5 (de) * | 1985-06-24 | 1988-07-29 | Ciba Geigy Ag | Feste, haltbare darreichungsformen mit elastischem filmueberzug. |
| US4816298A (en) * | 1987-11-27 | 1989-03-28 | The Dow Chemical Company | Method of making a granular, cold water dispersible coating composition |
| US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
| WO1993007859A1 (en) * | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
| US5271891A (en) * | 1992-07-20 | 1993-12-21 | General Motors Corporation | Method of sintering using polyphenylene oxide coated powdered metal |
| ES2185452B2 (es) * | 2000-08-01 | 2004-03-16 | Cinfa S A Lab | Composicion farmaceutica de fluoxetina en comprimido dispersable recubierto y su proceso de fabricacion. |
| EP1396263A1 (en) * | 2002-08-09 | 2004-03-10 | Warner-Lambert Company | Film coating for tablets and caplets |
| KR101598009B1 (ko) * | 2007-11-09 | 2016-02-29 | 다우 글로벌 테크놀로지스 엘엘씨 | 셀룰로스 에테르 피복 조성물 및 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5624648B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-06-24 | 1981-06-08 |
-
1975
- 1975-06-16 ZA ZA00753851A patent/ZA753851B/xx unknown
- 1975-06-25 IT IT24759/75A patent/IT1039400B/it active
- 1975-07-01 DE DE752529326A patent/DE2529326B2/de not_active Withdrawn
- 1975-07-22 BR BR7504662A patent/BR7504662A/pt unknown
- 1975-07-28 BE BE158691A patent/BE831823A/xx unknown
- 1975-07-31 FR FR7523963A patent/FR2288514A1/fr not_active Withdrawn
- 1975-08-01 JP JP50094127A patent/JPS5144624A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU8226375A (en) | 1976-12-23 |
| FR2288514A1 (fr) | 1976-05-21 |
| BR7504662A (pt) | 1976-08-31 |
| DE2529326A1 (de) | 1976-02-12 |
| BE831823A (fr) | 1976-01-28 |
| JPS5144624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-04-16 |
| IT1039400B (it) | 1979-12-10 |
| ZA753851B (en) | 1976-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BHJ | Nonpayment of the annual fee |