DE2524279A1 - Mittel zur intravaskulaeren verabreichung und verfahren zu seiner herstellung - Google Patents

Mittel zur intravaskulaeren verabreichung und verfahren zu seiner herstellung

Info

Publication number
DE2524279A1
DE2524279A1 DE19752524279 DE2524279A DE2524279A1 DE 2524279 A1 DE2524279 A1 DE 2524279A1 DE 19752524279 DE19752524279 DE 19752524279 DE 2524279 A DE2524279 A DE 2524279A DE 2524279 A1 DE2524279 A1 DE 2524279A1
Authority
DE
Germany
Prior art keywords
polysaccharide
particles
agent
water
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19752524279
Other languages
German (de)
English (en)
Other versions
DE2524279C2 (https=
Inventor
Bernt Jabes Lindberg
Ulv Sven Erik Dr Rothmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of DE2524279A1 publication Critical patent/DE2524279A1/de
Application granted granted Critical
Publication of DE2524279C2 publication Critical patent/DE2524279C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/003—Crosslinking of starch
    • C08B31/006—Crosslinking of derivatives of starch

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19752524279 1974-06-06 1975-05-31 Mittel zur intravaskulaeren verabreichung und verfahren zu seiner herstellung Granted DE2524279A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7407462A SE420565B (sv) 1974-06-06 1974-06-06 Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel

Publications (2)

Publication Number Publication Date
DE2524279A1 true DE2524279A1 (de) 1975-12-18
DE2524279C2 DE2524279C2 (https=) 1990-07-12

Family

ID=20321349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752524279 Granted DE2524279A1 (de) 1974-06-06 1975-05-31 Mittel zur intravaskulaeren verabreichung und verfahren zu seiner herstellung

Country Status (9)

Country Link
US (1) US4124705A (https=)
JP (1) JPS6125689B2 (https=)
AU (1) AU8164775A (https=)
CA (1) CA1037950A (https=)
DE (1) DE2524279A1 (https=)
FR (1) FR2273555A1 (https=)
GB (1) GB1518121A (https=)
NL (1) NL7506757A (https=)
SE (1) SE420565B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5283960A (en) * 1976-01-01 1977-07-13 Pharmacia Ab Medicine for administrating in blood
DE2908437A1 (de) * 1979-03-05 1980-09-18 Fresenius Chem Pharm Ind Vernetzte hydroxyaethylstaerke

Families Citing this family (68)

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US4276885A (en) * 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4385046A (en) * 1980-12-15 1983-05-24 Minnesota Mining And Manufacturing Company Diagnostic radio-labeled polysaccharide derivatives
US4431626A (en) * 1981-05-27 1984-02-14 The Regents Of The University Of California Tc-99m Labeled carrier for imaging
FR2548902B1 (fr) * 1983-07-13 1986-04-11 Guerbet Sa Gel pour embolisation therapeutique
SE463651B (sv) * 1983-12-21 1991-01-07 Nycomed As Diagnostikum och kontrastmedel
US5266333A (en) * 1985-03-06 1993-11-30 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration of growth hormone
US4680171A (en) * 1985-03-15 1987-07-14 William Shell Visualization of a bloodstream circulation with biodegradable microspheres
JPS62236839A (ja) * 1986-04-08 1987-10-16 Yoshiaki Motozato 架橋されたグルコマンナン球状粒子及びその製法
GB8801646D0 (en) * 1988-01-26 1988-02-24 Nycomed As Chemical compounds
US5948387A (en) * 1990-06-01 1999-09-07 Imarx Pharmaceutical Corp. Contrast media for ultrasonic imaging
US5420176A (en) * 1990-06-01 1995-05-30 Imarx Pharmaceutical Corp. Contrast media for ultrasonic imaging
ATE130517T1 (de) * 1990-08-08 1995-12-15 Takeda Chemical Industries Ltd Intravaskulär embolisierendes mittel mit gehalt an einem die angiogenesis hemmenden stoff.
US5603956A (en) * 1990-11-27 1997-02-18 Labopharm Inc. Cross-linked enzymatically controlled drug release
US5233995A (en) * 1991-11-21 1993-08-10 Sterling Winthrop Inc. Encapsulated particles useful as contrast agents in ultrasound and x-ray imaging compositions and methods
DE69302580T2 (de) * 1992-07-24 1996-09-26 Labopharm Inc., Ste-Therese, Quebec Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
SE9303574D0 (sv) * 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
EP0830416B1 (en) * 1995-06-06 2005-08-31 C.R. Bard, Inc. Process for the preparation of crosslinked particles of water soluble polymers, the particles obtained and their use
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6261320B1 (en) 1996-11-21 2001-07-17 Radiance Medical Systems, Inc. Radioactive vascular liner
US6458069B1 (en) 1998-02-19 2002-10-01 Endology, Inc. Multi layer radiation delivery balloon
US5782742A (en) 1997-01-31 1998-07-21 Cardiovascular Dynamics, Inc. Radiation delivery balloon
US6491619B1 (en) 1997-01-31 2002-12-10 Endologix, Inc Radiation delivery catheters and dosimetry methods
US5993374A (en) * 1997-06-17 1999-11-30 Radiance Medical Systems, Inc. Microcapsules for site-specific delivery
US6048299A (en) * 1997-11-07 2000-04-11 Radiance Medical Systems, Inc. Radiation delivery catheter
US6149574A (en) * 1997-12-19 2000-11-21 Radiance Medical Systems, Inc. Dual catheter radiation delivery system
EP1056515A1 (en) 1998-02-19 2000-12-06 Radiance Medical Systems Inc. Radioactive stent
US6203778B1 (en) * 1998-12-08 2001-03-20 The Regents Of The University Of California Particulate radiopaque contrast agent for diagnostic imaging and microvascular characterization
IL151058A0 (en) 2000-02-08 2003-04-10 Euro Celtique Sa Controlled-release compositions containing opioid agonist and antagonist
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
JP4885866B2 (ja) 2004-10-25 2012-02-29 セロノヴァ バイオサイエンスィズ ジャーマニー ゲーエムベーハー 治療適用および／または診断適用のための充填可能なポリホスファゼン含有粒子、ならびにその調製方法および使用方法
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
MX2008014847A (es) 2006-05-31 2009-04-30 Baxter Int Metodo para crecimiento interno en la celula dirigido y regeneracion controlada de los tejidos en la cirugia espinal.
TWI436793B (zh) 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
US8623842B2 (en) 2006-09-27 2014-01-07 Hemostasis, Llc Hemostatic agent and method
CL2008003219A1 (es) 2007-10-30 2009-10-09 Baxter Int Uso de una biomatriz de colageno biofuncional, multicapas y no porosa, que dirige el crecimiento celular dentro de los intersticios de la biomatriz de colageno, para tratar un defecto de una membrana visceral o parietal; y biomatriz utilizada.
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
US9061087B2 (en) * 2008-03-04 2015-06-23 Hemostasis, Llc Method of making a hemostatic sponge wound dressing comprising subjecting the sponge to water vapor
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
BRPI1015979A8 (pt) 2009-06-16 2018-06-19 Baxter Healthcare Sa esponja porosa hemostática, e, método para fabricar uma esponja porosa hemostática
CA2772023A1 (en) 2009-08-18 2011-02-24 Ben Gurion University Of The Negev Research And Development Authority System and method for analyzing imaging data
US8771258B2 (en) 2009-12-16 2014-07-08 Baxter International Inc. Hemostatic sponge
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
KR101957625B1 (ko) 2010-06-01 2019-03-12 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
ES2676208T3 (es) 2010-06-01 2018-07-17 Baxter International Inc. Proceso para la producción de composiciones hemostáticas secas y estables
CA2801120C (en) 2010-06-01 2019-08-20 Baxter International Inc. Process for making dry and stable hemostatic compositions
US9381269B2 (en) 2011-04-13 2016-07-05 Avent, Inc. Biosorbable wound treatment device, process for making, and method of using the same
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 止血組成物
ES2938566T3 (es) 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
PT2771027E (pt) 2011-10-27 2015-11-26 Baxter Healthcare Sa Composições hemostáticas
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
EP2977066A3 (en) 2012-06-12 2016-07-27 Ferrosan Medical Devices A/S Dry haemostatic composition
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
AU2015333206B2 (en) 2014-10-13 2019-07-11 Ferrosan Medical Devices A/S. Dry composition for use in haemostasis and wound healing
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
CN107771093B (zh) 2015-07-03 2021-06-15 弗罗桑医疗设备公司 用于混合两种组分和用于在存储条件下保持真空的注射器
JP6523510B1 (ja) 2018-03-30 2019-06-05 Ｊｘ金属株式会社 スパッタリングターゲット
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2626257A (en) * 1952-05-21 1953-01-20 Johnson & Johnson Medical dusting powder
DE1916704A1 (de) * 1968-04-01 1969-11-06 Minnesota Mining & Mfg Biologisch zersetzbare radioaktive Teilchen
DE2201669A1 (de) * 1971-08-21 1973-02-22 Kyorin Seiyaku Kk Pyrogenfreier blutplasmaersatz und verfahren zu seiner herstellung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL126243C (https=) * 1959-06-12

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2626257A (en) * 1952-05-21 1953-01-20 Johnson & Johnson Medical dusting powder
DE1916704A1 (de) * 1968-04-01 1969-11-06 Minnesota Mining & Mfg Biologisch zersetzbare radioaktive Teilchen
DE2201669A1 (de) * 1971-08-21 1973-02-22 Kyorin Seiyaku Kk Pyrogenfreier blutplasmaersatz und verfahren zu seiner herstellung

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5283960A (en) * 1976-01-01 1977-07-13 Pharmacia Ab Medicine for administrating in blood
DE2908437A1 (de) * 1979-03-05 1980-09-18 Fresenius Chem Pharm Ind Vernetzte hydroxyaethylstaerke

Also Published As

Publication number Publication date
FR2273555B1 (https=) 1978-10-06
JPS517115A (https=) 1976-01-21
FR2273555A1 (fr) 1976-01-02
DE2524279C2 (https=) 1990-07-12
GB1518121A (en) 1978-07-19
NL7506757A (nl) 1975-12-09
AU8164775A (en) 1976-12-02
SE7407462L (sv) 1975-12-08
JPS6125689B2 (https=) 1986-06-17
US4124705A (en) 1978-11-07
CA1037950A (en) 1978-09-05
SE420565B (sv) 1981-10-19

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8126 Change of the secondary classification

Free format text: A61K 9/10 A61K 49/02 A61K 49/04 A61K 43/00

D2 Grant after examination
8364 No opposition during term of opposition