DE2501787A1 - Verfahren zur herstellung von wismuthaltigen arzneipraeparaten - Google Patents

Verfahren zur herstellung von wismuthaltigen arzneipraeparaten

Info

Publication number
DE2501787A1
DE2501787A1 DE19752501787 DE2501787A DE2501787A1 DE 2501787 A1 DE2501787 A1 DE 2501787A1 DE 19752501787 DE19752501787 DE 19752501787 DE 2501787 A DE2501787 A DE 2501787A DE 2501787 A1 DE2501787 A1 DE 2501787A1
Authority
DE
Germany
Prior art keywords
medicinal preparations
dry powder
bismuth
preparations
preheated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19752501787
Other languages
German (de)
English (en)
Other versions
DE2501787C2 (xx
Inventor
Ross Brock Himstedt
Cristopher John Mcloughlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brocades-Pharma Bv Leiderdorp Nl
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of DE2501787A1 publication Critical patent/DE2501787A1/de
Application granted granted Critical
Publication of DE2501787C2 publication Critical patent/DE2501787C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/29—Antimony or bismuth compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/02—Ammonia; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19752501787 1974-01-18 1975-01-17 Verfahren zur herstellung von wismuthaltigen arzneipraeparaten Granted DE2501787A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA00740385A ZA74385B (en) 1974-01-18 1974-01-18 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE2501787A1 true DE2501787A1 (de) 1975-07-24
DE2501787C2 DE2501787C2 (xx) 1987-11-12

Family

ID=25567281

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752501787 Granted DE2501787A1 (de) 1974-01-18 1975-01-17 Verfahren zur herstellung von wismuthaltigen arzneipraeparaten

Country Status (18)

Country Link
JP (1) JPS5837284B2 (xx)
AT (1) AT349150B (xx)
AU (1) AU485660B2 (xx)
BE (1) BE824509A (xx)
CA (1) CA1040532A (xx)
CH (1) CH622947A5 (xx)
DE (1) DE2501787A1 (xx)
DK (1) DK151770C (xx)
ES (1) ES433908A1 (xx)
FI (1) FI750113A (xx)
FR (1) FR2258177B1 (xx)
GB (1) GB1478742A (xx)
IE (1) IE40361B1 (xx)
IT (1) IT1036072B (xx)
LU (1) LU71668A1 (xx)
NL (1) NL185130C (xx)
SE (1) SE437930B (xx)
ZA (1) ZA74385B (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2907215A1 (de) * 1978-02-24 1979-09-06 Novex Foreign Trade Co Ltd Feste depotarzneimittelpraeparate und verfahren zu deren herstellung
EP0363502A1 (de) * 1988-10-08 1990-04-18 Dr. R. Pfleger Chemische Fabrik Gmbh Flüssiges, wismuthaltiges Arzneipräparat, Verfahren zum Herstellen desselben und seine Verwendung
US5843482A (en) * 1990-07-20 1998-12-01 Tillotts Pharma Ag Products and processes for the treatment of the alimentary canal

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801608A (en) * 1981-09-22 1989-01-31 Gist-Brocades N. V. Bismuth containing composition and method for the preparation thereof
PT75550B (en) * 1981-09-22 1984-12-12 Gist Brocades Nv Bismuth containing composition and method for the preparation thereof
EP0222834A4 (en) * 1985-04-18 1989-10-04 Borody Thomas J TREATMENT OF NON-ULCERATIVE DYSPEPSIA WITH BISMUTOUS SALTS.
US4748113A (en) * 1985-06-13 1988-05-31 Marshall Barry J Compositions and methods for the diagnosis of gastrointestinal disorders involving urease
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
DE3686362T2 (de) * 1985-06-13 1993-02-11 Marshall Barry James Verfahren zur behandlung von magen-darmstoerungen.
EP0462631B1 (en) * 1985-06-13 1996-03-20 Barry James Dr. Marshall Methods and compositions for the treatment of gastrointestinal disorders
DE3901508C2 (de) * 1989-01-19 1994-04-07 Falk Pharma Gmbh Arzneimittel auf der Grundlage eines Wismut enthaltenden Präparats in fester Form
IT1229502B (it) * 1989-01-25 1991-09-03 Euroresearch Srl Composizioni contenenti bismuto idonee per uso terapeutico.
IE893167A1 (en) * 1989-10-04 1991-04-24 Ulso Lab Ltd Preparation of orally administrable liquids for use in¹therapy
US5192752A (en) * 1991-01-14 1993-03-09 The Procter & Gamble Company Swallowable pharmaceutical compositions containing colloidal bismuth subcitrate
US6902738B2 (en) 1994-05-02 2005-06-07 Josman Laboratories, Inc. Topical oral dosage forms containing bismuth compounds
US5834002A (en) 1994-05-02 1998-11-10 Josman Laboratories, Inc. Chewing gum containing colloidal bismuth subcitrate
US6426085B1 (en) 1994-05-02 2002-07-30 Josman Laboratories Inc. Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis
US6379651B1 (en) 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
US6372784B1 (en) 1995-02-07 2002-04-16 Josman Laboratories, Inc. Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds
MX9703918A (es) 1997-05-28 1998-11-30 J Marshall M D Barry Procedimiento para preparar un producto farmaceutico reactivo para deteccion de desorden gastrointestinal causado por bacteria en el tracto gastrointestinal superior.
US7008777B2 (en) 2001-10-15 2006-03-07 Barry J. Marshall System for the detection of urease and method for using same
US6998250B2 (en) 2001-10-15 2006-02-14 Donald J. McMichael Method for detecting Helicobacter pylori
USD484988S1 (en) 2001-12-17 2004-01-06 Kimberly-Clark Worldwide, Inc. Diagnostic test kit with specimen-handling tool
US6783976B2 (en) 2001-12-21 2004-08-31 Kimberly-Clark Worldwide, Inc. Carrier and specimen-handling tool for use in diagnostic testing

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1900268A1 (de) * 1968-12-23 1969-09-04 Serfontein Willem Jacob Wismuth-Komplex-Praeparat
DE1963781A1 (de) * 1968-12-23 1970-07-09 Serfontein Willem Jacob Verbesserte Wismuth-Praeparate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1900268A1 (de) * 1968-12-23 1969-09-04 Serfontein Willem Jacob Wismuth-Komplex-Praeparat
DE1963781A1 (de) * 1968-12-23 1970-07-09 Serfontein Willem Jacob Verbesserte Wismuth-Praeparate

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GSTIRNER, FRITZ: Einführung in die Verfahrenstech-nik der Arzneiforschung, 5. Aufl., Wiss. Verlags- ges. mbH, Stuttgart 1973, S.369-370 *
MASTERS, KEITH: Industrial Engineering Chemistry Vol. 60, No. 10, October 1968, S.53-63 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2907215A1 (de) * 1978-02-24 1979-09-06 Novex Foreign Trade Co Ltd Feste depotarzneimittelpraeparate und verfahren zu deren herstellung
EP0363502A1 (de) * 1988-10-08 1990-04-18 Dr. R. Pfleger Chemische Fabrik Gmbh Flüssiges, wismuthaltiges Arzneipräparat, Verfahren zum Herstellen desselben und seine Verwendung
US5064857A (en) * 1988-10-08 1991-11-12 R. Pfleger Chemische Fabrik Gmbh Liquid bismuth containing medicinal product, process for producing it and its use
US5843482A (en) * 1990-07-20 1998-12-01 Tillotts Pharma Ag Products and processes for the treatment of the alimentary canal

Also Published As

Publication number Publication date
ES433908A1 (es) 1976-11-16
LU71668A1 (xx) 1975-06-24
FI750113A (xx) 1975-07-19
NL185130C (nl) 1990-02-01
SE437930B (sv) 1985-03-25
BE824509A (fr) 1975-07-17
AT349150B (de) 1979-03-26
DK151770B (da) 1988-01-04
JPS5837284B2 (ja) 1983-08-15
AU485660B2 (en) 1977-07-28
SE7500501L (xx) 1975-07-21
NL185130B (nl) 1989-09-01
FR2258177A1 (xx) 1975-08-18
IE40361B1 (en) 1979-05-09
IE40361L (en) 1975-07-18
CH622947A5 (en) 1981-05-15
AU7729375A (en) 1976-07-15
CA1040532A (en) 1978-10-17
FR2258177B1 (xx) 1978-07-21
IT1036072B (it) 1979-10-30
NL7500552A (nl) 1975-07-22
JPS50116623A (xx) 1975-09-12
ZA74385B (en) 1975-08-27
ATA31875A (de) 1978-08-15
GB1478742A (en) 1977-07-06
DE2501787C2 (xx) 1987-11-12
DK151770C (da) 1989-11-06
DK12675A (xx) 1975-09-15

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BROCADES-PHARMA B.V., LEIDERDORP, NL

8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT. HERMANN, G., DIPL.-PHYS. DR.RER.NAT. SCHMIDT, J., DIPL.-ING. JAENICHEN, H., DIPL.-BIOL. DR.RER.NAT., PAT.-ANWAELTE TREMMEL, H., RECHTSANW., 8000 MUENCHEN