GB1478742A - Pharmaceutical compositions and their preparation - Google Patents

Pharmaceutical compositions and their preparation

Info

Publication number
GB1478742A
GB1478742A GB2146/75A GB214675A GB1478742A GB 1478742 A GB1478742 A GB 1478742A GB 2146/75 A GB2146/75 A GB 2146/75A GB 214675 A GB214675 A GB 214675A GB 1478742 A GB1478742 A GB 1478742A
Authority
GB
United Kingdom
Prior art keywords
dry powder
bismuth
pharmaceutical compositions
jan
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2146/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of GB1478742A publication Critical patent/GB1478742A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/29—Antimony or bismuth compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/02—Ammonia; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1478742 Bismuth-containing antacids GISTBROCADES NV 17 Jan 1975 [18 Jan 1974] 2146/75 Heading A5B A solid bismuth-containing powder for use in the treatment of peptic ulcer is prepared by spray-drying an aqueous, colloidal solution comprising bismuth citrate, ammonia and a non-toxic polyhydric alcohol e.g. sucrose or maltose, to produce a dry powder. Pharmaceutical compositions for oral administration comprise (1) the dry powder optionally together with pharmaceutically-acceptable carrier(s) and may be in the form of tablets or capsules or (2) a liquid obtained by dissolving the dry powder in water. The liquid starting material optionally contains pepsin, a colouring agent such as carmine, an alkali metal (e.g. sodium or potassium) hydroxide and a preservative.
GB2146/75A 1974-01-18 1975-01-17 Pharmaceutical compositions and their preparation Expired GB1478742A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA00740385A ZA74385B (en) 1974-01-18 1974-01-18 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
GB1478742A true GB1478742A (en) 1977-07-06

Family

ID=25567281

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2146/75A Expired GB1478742A (en) 1974-01-18 1975-01-17 Pharmaceutical compositions and their preparation

Country Status (18)

Country Link
JP (1) JPS5837284B2 (en)
AT (1) AT349150B (en)
AU (1) AU485660B2 (en)
BE (1) BE824509A (en)
CA (1) CA1040532A (en)
CH (1) CH622947A5 (en)
DE (1) DE2501787A1 (en)
DK (1) DK151770C (en)
ES (1) ES433908A1 (en)
FI (1) FI750113A (en)
FR (1) FR2258177B1 (en)
GB (1) GB1478742A (en)
IE (1) IE40361B1 (en)
IT (1) IT1036072B (en)
LU (1) LU71668A1 (en)
NL (1) NL185130C (en)
SE (1) SE437930B (en)
ZA (1) ZA74385B (en)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983001001A1 (en) * 1981-09-22 1983-03-31 Gist Brocades Nv Bismuth containing composition and method for the preparation thereof
DE3619734A1 (en) * 1985-06-13 1987-02-12 Barry James Marshall AGENT FOR TREATMENT OF GASTRONIC DISEASES
DE3619702A1 (en) * 1985-06-13 1987-02-12 Barry James Marshall METHOD AND COMPOSITIONS FOR THE TREATMENT OF STOMESTRAL DISEASES
US4748113A (en) * 1985-06-13 1988-05-31 Marshall Barry J Compositions and methods for the diagnosis of gastrointestinal disorders involving urease
US4801608A (en) * 1981-09-22 1989-01-31 Gist-Brocades N. V. Bismuth containing composition and method for the preparation thereof
GB2236479A (en) * 1989-10-04 1991-04-10 Ulso Lab Limited Preparation of orally administrable bismuth ammonium citrate solutions
US5192752A (en) * 1991-01-14 1993-03-09 The Procter & Gamble Company Swallowable pharmaceutical compositions containing colloidal bismuth subcitrate
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
US6372784B1 (en) 1995-02-07 2002-04-16 Josman Laboratories, Inc. Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds
US6379651B1 (en) 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
US6426085B1 (en) 1994-05-02 2002-07-30 Josman Laboratories Inc. Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis
US6517809B1 (en) 1997-05-28 2003-02-11 Barry J. Marshall Process for preparing a reactive pharmaceutical product for the detection of gastrointestinal disorder caused by bacteria in the gastrointestinal superior tract
US6616938B2 (en) 1994-05-02 2003-09-09 Josman Laboratories, Inc. Method of making chewing gum containing colloidal bismuth subcitrate
USD484988S1 (en) 2001-12-17 2004-01-06 Kimberly-Clark Worldwide, Inc. Diagnostic test kit with specimen-handling tool
US6783976B2 (en) 2001-12-21 2004-08-31 Kimberly-Clark Worldwide, Inc. Carrier and specimen-handling tool for use in diagnostic testing
US6902738B2 (en) 1994-05-02 2005-06-07 Josman Laboratories, Inc. Topical oral dosage forms containing bismuth compounds
US6998250B2 (en) 2001-10-15 2006-02-14 Donald J. McMichael Method for detecting Helicobacter pylori
US7008777B2 (en) 2001-10-15 2006-03-07 Barry J. Marshall System for the detection of urease and method for using same

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179474B (en) * 1978-02-24 1982-10-28 Laszlo Gyarmati Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material
AU590578B2 (en) * 1985-04-18 1989-11-09 Procter & Gamble Company, The Treatment of non-ulcer dyspepsia with bismuth salts
EP0363502B1 (en) * 1988-10-08 1991-09-25 Dr. R. Pfleger Chemische Fabrik Gmbh Liquid formulation containing bismuth, process to prepare it and use thereof
DE3901508C2 (en) * 1989-01-19 1994-04-07 Falk Pharma Gmbh Drug based on a bismuth-containing preparation in solid form
IT1229502B (en) * 1989-01-25 1991-09-03 Euroresearch Srl COMPOSITIONS CONTAINING BISMUTO SUITABLE FOR THERAPEUTIC USE.
ES2084174T3 (en) * 1990-07-20 1996-05-01 Tillotts Pharma Ag PRODUCTS AND PROCESSES FOR THE TREATMENT OF THE FOOD DUCT.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963781A1 (en) * 1968-12-23 1970-07-09 Serfontein Willem Jacob Improved bismuth preparations
GB1259151A (en) * 1968-12-23 1972-01-05 Willem Jacob Serfontein Bismuth complexes

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801608A (en) * 1981-09-22 1989-01-31 Gist-Brocades N. V. Bismuth containing composition and method for the preparation thereof
EP0075992A1 (en) * 1981-09-22 1983-04-06 Gist-Brocades N.V. Bismuth containing composition and method for the preparation thereof
WO1983001001A1 (en) * 1981-09-22 1983-03-31 Gist Brocades Nv Bismuth containing composition and method for the preparation thereof
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
DE3619702A1 (en) * 1985-06-13 1987-02-12 Barry James Marshall METHOD AND COMPOSITIONS FOR THE TREATMENT OF STOMESTRAL DISEASES
US4748113A (en) * 1985-06-13 1988-05-31 Marshall Barry J Compositions and methods for the diagnosis of gastrointestinal disorders involving urease
DE3619733A1 (en) * 1985-06-13 1987-02-12 Barry James Marshall AGENT FOR TREATMENT OF GASTRONIC DISEASES
DE3619734A1 (en) * 1985-06-13 1987-02-12 Barry James Marshall AGENT FOR TREATMENT OF GASTRONIC DISEASES
US5601848A (en) * 1985-06-13 1997-02-11 The Procter & Gamble Company Methods for the treatment of gastrointestinal disorders
GB2236479A (en) * 1989-10-04 1991-04-10 Ulso Lab Limited Preparation of orally administrable bismuth ammonium citrate solutions
GB2236479B (en) * 1989-10-04 1993-06-23 Ulso Lab Limited Preparation of orally administrable bismuth ammonium citrate solutions
US5192752A (en) * 1991-01-14 1993-03-09 The Procter & Gamble Company Swallowable pharmaceutical compositions containing colloidal bismuth subcitrate
US6616938B2 (en) 1994-05-02 2003-09-09 Josman Laboratories, Inc. Method of making chewing gum containing colloidal bismuth subcitrate
US6426085B1 (en) 1994-05-02 2002-07-30 Josman Laboratories Inc. Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis
US6902738B2 (en) 1994-05-02 2005-06-07 Josman Laboratories, Inc. Topical oral dosage forms containing bismuth compounds
US6379651B1 (en) 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
US6372784B1 (en) 1995-02-07 2002-04-16 Josman Laboratories, Inc. Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds
US6517809B1 (en) 1997-05-28 2003-02-11 Barry J. Marshall Process for preparing a reactive pharmaceutical product for the detection of gastrointestinal disorder caused by bacteria in the gastrointestinal superior tract
US6998250B2 (en) 2001-10-15 2006-02-14 Donald J. McMichael Method for detecting Helicobacter pylori
US7008777B2 (en) 2001-10-15 2006-03-07 Barry J. Marshall System for the detection of urease and method for using same
USD484988S1 (en) 2001-12-17 2004-01-06 Kimberly-Clark Worldwide, Inc. Diagnostic test kit with specimen-handling tool
US6783976B2 (en) 2001-12-21 2004-08-31 Kimberly-Clark Worldwide, Inc. Carrier and specimen-handling tool for use in diagnostic testing

Also Published As

Publication number Publication date
AU7729375A (en) 1976-07-15
DK151770C (en) 1989-11-06
SE7500501L (en) 1975-07-21
DK151770B (en) 1988-01-04
IT1036072B (en) 1979-10-30
IE40361B1 (en) 1979-05-09
FR2258177B1 (en) 1978-07-21
NL185130C (en) 1990-02-01
FR2258177A1 (en) 1975-08-18
CA1040532A (en) 1978-10-17
LU71668A1 (en) 1975-06-24
DE2501787A1 (en) 1975-07-24
DE2501787C2 (en) 1987-11-12
AU485660B2 (en) 1977-07-28
SE437930B (en) 1985-03-25
ZA74385B (en) 1975-08-27
CH622947A5 (en) 1981-05-15
JPS5837284B2 (en) 1983-08-15
NL185130B (en) 1989-09-01
NL7500552A (en) 1975-07-22
IE40361L (en) 1975-07-18
JPS50116623A (en) 1975-09-12
BE824509A (en) 1975-07-17
ATA31875A (en) 1978-08-15
AT349150B (en) 1979-03-26
DK12675A (en) 1975-09-15
ES433908A1 (en) 1976-11-16
FI750113A (en) 1975-07-19

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Legal Events

Date Code Title Description
PS Patent sealed
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940117