JPS55108814A - Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use - Google Patents

Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use

Info

Publication number
JPS55108814A
JPS55108814A JP1433879A JP1433879A JPS55108814A JP S55108814 A JPS55108814 A JP S55108814A JP 1433879 A JP1433879 A JP 1433879A JP 1433879 A JP1433879 A JP 1433879A JP S55108814 A JPS55108814 A JP S55108814A
Authority
JP
Japan
Prior art keywords
powder
easily soluble
stable
preparation
magnesium citrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1433879A
Other languages
Japanese (ja)
Other versions
JPS5748528B2 (en
Inventor
Yukio Matsubara
Noboru Yamamoto
Minoru Okuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HORII PHARMA IND
HORII YAKUHIN KOGYO KK
Fuji Chemical Industries Co Ltd
Original Assignee
HORII PHARMA IND
HORII YAKUHIN KOGYO KK
Fuji Chemical Industries Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HORII PHARMA IND, HORII YAKUHIN KOGYO KK, Fuji Chemical Industries Co Ltd filed Critical HORII PHARMA IND
Priority to JP1433879A priority Critical patent/JPS55108814A/en
Publication of JPS55108814A publication Critical patent/JPS55108814A/en
Publication of JPS5748528B2 publication Critical patent/JPS5748528B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare the title powder having high storage stability, by spray-drying or freeze-drying the reaction mixture obtained by reacting metallic magnesium or a basic magnesium salt with citric acid in an aqueous medium.
CONSTITUTION: Metallic magnesium or a basic magnesium salt is reacted with an equi-molar amount of citric acid in an aqueous medium, and if necessary, neutralized with the hydroxide or a physiologically permissible salt of sodium or potassium. Immediately after the reaction, the product is spray-dried or freeze-dried to obtain the title powder. Since the powder thus prepared is easily soluble compared with crystalline magnesium citrate, it can be taken, in place of a liquid preparation, by dissolving in water before use.
COPYRIGHT: (C)1980,JPO&Japio
JP1433879A 1979-02-13 1979-02-13 Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use Granted JPS55108814A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1433879A JPS55108814A (en) 1979-02-13 1979-02-13 Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1433879A JPS55108814A (en) 1979-02-13 1979-02-13 Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use

Publications (2)

Publication Number Publication Date
JPS55108814A true JPS55108814A (en) 1980-08-21
JPS5748528B2 JPS5748528B2 (en) 1982-10-16

Family

ID=11858270

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1433879A Granted JPS55108814A (en) 1979-02-13 1979-02-13 Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use

Country Status (1)

Country Link
JP (1) JPS55108814A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895980A (en) * 1988-01-05 1990-01-23 Mission Pharmacal Company, Inc. Method of manufacturing magnesium potassium citrate
US4985593A (en) * 1988-01-05 1991-01-15 Mission Pharmacal Company, Inc. Magnesium potassium citrate
US5219889A (en) * 1988-01-05 1993-06-15 The University Of Texas System Dietary supplementation with potassium magnesium citrate
RU2756322C1 (en) * 2020-12-29 2021-09-29 Федеральное государственное бюджетное учреждение науки Институт общей и неорганической химии им. Н.С. Курнакова Российской академии наук (ИОНХ РАН) Method for obtaining amorphous water-soluble salts of magnesium citrate

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895980A (en) * 1988-01-05 1990-01-23 Mission Pharmacal Company, Inc. Method of manufacturing magnesium potassium citrate
US4985593A (en) * 1988-01-05 1991-01-15 Mission Pharmacal Company, Inc. Magnesium potassium citrate
US5219889A (en) * 1988-01-05 1993-06-15 The University Of Texas System Dietary supplementation with potassium magnesium citrate
US5432200A (en) * 1988-01-05 1995-07-11 Walsdorf; Neill B. Method for increasing urinary excretion of electrolytes
RU2756322C1 (en) * 2020-12-29 2021-09-29 Федеральное государственное бюджетное учреждение науки Институт общей и неорганической химии им. Н.С. Курнакова Российской академии наук (ИОНХ РАН) Method for obtaining amorphous water-soluble salts of magnesium citrate

Also Published As

Publication number Publication date
JPS5748528B2 (en) 1982-10-16

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