JPS55108814A - Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use - Google Patents
Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical useInfo
- Publication number
- JPS55108814A JPS55108814A JP1433879A JP1433879A JPS55108814A JP S55108814 A JPS55108814 A JP S55108814A JP 1433879 A JP1433879 A JP 1433879A JP 1433879 A JP1433879 A JP 1433879A JP S55108814 A JPS55108814 A JP S55108814A
- Authority
- JP
- Japan
- Prior art keywords
- powder
- easily soluble
- stable
- preparation
- magnesium citrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare the title powder having high storage stability, by spray-drying or freeze-drying the reaction mixture obtained by reacting metallic magnesium or a basic magnesium salt with citric acid in an aqueous medium.
CONSTITUTION: Metallic magnesium or a basic magnesium salt is reacted with an equi-molar amount of citric acid in an aqueous medium, and if necessary, neutralized with the hydroxide or a physiologically permissible salt of sodium or potassium. Immediately after the reaction, the product is spray-dried or freeze-dried to obtain the title powder. Since the powder thus prepared is easily soluble compared with crystalline magnesium citrate, it can be taken, in place of a liquid preparation, by dissolving in water before use.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1433879A JPS55108814A (en) | 1979-02-13 | 1979-02-13 | Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1433879A JPS55108814A (en) | 1979-02-13 | 1979-02-13 | Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55108814A true JPS55108814A (en) | 1980-08-21 |
JPS5748528B2 JPS5748528B2 (en) | 1982-10-16 |
Family
ID=11858270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1433879A Granted JPS55108814A (en) | 1979-02-13 | 1979-02-13 | Preparation of stable, easily soluble, amorphous magnesium citrate powder for medical use |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55108814A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4895980A (en) * | 1988-01-05 | 1990-01-23 | Mission Pharmacal Company, Inc. | Method of manufacturing magnesium potassium citrate |
US4985593A (en) * | 1988-01-05 | 1991-01-15 | Mission Pharmacal Company, Inc. | Magnesium potassium citrate |
US5219889A (en) * | 1988-01-05 | 1993-06-15 | The University Of Texas System | Dietary supplementation with potassium magnesium citrate |
RU2756322C1 (en) * | 2020-12-29 | 2021-09-29 | Федеральное государственное бюджетное учреждение науки Институт общей и неорганической химии им. Н.С. Курнакова Российской академии наук (ИОНХ РАН) | Method for obtaining amorphous water-soluble salts of magnesium citrate |
-
1979
- 1979-02-13 JP JP1433879A patent/JPS55108814A/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4895980A (en) * | 1988-01-05 | 1990-01-23 | Mission Pharmacal Company, Inc. | Method of manufacturing magnesium potassium citrate |
US4985593A (en) * | 1988-01-05 | 1991-01-15 | Mission Pharmacal Company, Inc. | Magnesium potassium citrate |
US5219889A (en) * | 1988-01-05 | 1993-06-15 | The University Of Texas System | Dietary supplementation with potassium magnesium citrate |
US5432200A (en) * | 1988-01-05 | 1995-07-11 | Walsdorf; Neill B. | Method for increasing urinary excretion of electrolytes |
RU2756322C1 (en) * | 2020-12-29 | 2021-09-29 | Федеральное государственное бюджетное учреждение науки Институт общей и неорганической химии им. Н.С. Курнакова Российской академии наук (ИОНХ РАН) | Method for obtaining amorphous water-soluble salts of magnesium citrate |
Also Published As
Publication number | Publication date |
---|---|
JPS5748528B2 (en) | 1982-10-16 |
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