JPS5550863A - Preparation of water-soluble biotin pharmaceutical - Google Patents

Preparation of water-soluble biotin pharmaceutical

Info

Publication number
JPS5550863A
JPS5550863A JP12541778A JP12541778A JPS5550863A JP S5550863 A JPS5550863 A JP S5550863A JP 12541778 A JP12541778 A JP 12541778A JP 12541778 A JP12541778 A JP 12541778A JP S5550863 A JPS5550863 A JP S5550863A
Authority
JP
Japan
Prior art keywords
water
pharmaceutical
biotin
preparation
soluble biotin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12541778A
Other languages
Japanese (ja)
Other versions
JPS6125688B2 (en
Inventor
Takayoshi Mitsunaga
Kiyoto Jinushi
Tadashi Umetsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP12541778A priority Critical patent/JPS5550863A/en
Publication of JPS5550863A publication Critical patent/JPS5550863A/en
Publication of JPS6125688B2 publication Critical patent/JPS6125688B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To impart the water-solubility to Biotin which is slightly soluble in water, and to improve the compatibility with feed and the absorption and utilization in vivo in administration, by using a specific preparation method.
CONSTITUTION: An aqueous solution of pH5W9 comprising (A) Biotin, (B) lactose, and (C) ammonia at a weight ratio of (A) to (B) of 1:4W100, the amount of (C) being enough to dissolve (A), is spray-dried to give the desired fine spherical pharmaceutical having a particle size of about 5W40μ.
EFFECT: The non-hygroscopic pharmaceutical will not cake.
COPYRIGHT: (C)1980,JPO&Japio
JP12541778A 1978-10-11 1978-10-11 Preparation of water-soluble biotin pharmaceutical Granted JPS5550863A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12541778A JPS5550863A (en) 1978-10-11 1978-10-11 Preparation of water-soluble biotin pharmaceutical

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12541778A JPS5550863A (en) 1978-10-11 1978-10-11 Preparation of water-soluble biotin pharmaceutical

Publications (2)

Publication Number Publication Date
JPS5550863A true JPS5550863A (en) 1980-04-14
JPS6125688B2 JPS6125688B2 (en) 1986-06-17

Family

ID=14909580

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12541778A Granted JPS5550863A (en) 1978-10-11 1978-10-11 Preparation of water-soluble biotin pharmaceutical

Country Status (1)

Country Link
JP (1) JPS5550863A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60167846A (en) * 1984-02-06 1985-08-31 Yoshida Kogyo Kk <Ykk> Low-tension transfer device
US5814650A (en) * 1992-09-28 1998-09-29 Lifegroup S.P.A. Biotin amides able to control glucidic metabolisms under dysmetabolic conditions and relative therapeutical compositions

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62142113U (en) * 1986-02-28 1987-09-08
JPH01155596U (en) * 1988-04-15 1989-10-25
US20170135969A1 (en) 2015-11-12 2017-05-18 Jds Therapeutics, Llc Topical arginine-silicate-inositol for wound healing
AU2017318672B2 (en) * 2016-09-01 2022-03-10 Nutrition 21, Llc Magnesium biotinate compositions and methods of use

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60167846A (en) * 1984-02-06 1985-08-31 Yoshida Kogyo Kk <Ykk> Low-tension transfer device
JPH0155176B2 (en) * 1984-02-06 1989-11-22 Yoshida Kogyo Kk
US5814650A (en) * 1992-09-28 1998-09-29 Lifegroup S.P.A. Biotin amides able to control glucidic metabolisms under dysmetabolic conditions and relative therapeutical compositions

Also Published As

Publication number Publication date
JPS6125688B2 (en) 1986-06-17

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