DE2456586C3 - Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiert - Google Patents
Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiertInfo
- Publication number
- DE2456586C3 DE2456586C3 DE2456586A DE2456586A DE2456586C3 DE 2456586 C3 DE2456586 C3 DE 2456586C3 DE 2456586 A DE2456586 A DE 2456586A DE 2456586 A DE2456586 A DE 2456586A DE 2456586 C3 DE2456586 C3 DE 2456586C3
- Authority
- DE
- Germany
- Prior art keywords
- cholesterol
- microorganisms
- cholestenone
- oxidizes
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title claims description 22
- 235000012000 cholesterol Nutrition 0.000 title claims description 11
- 108010089254 Cholesterol oxidase Proteins 0.000 title claims description 7
- 244000005700 microbiome Species 0.000 title description 13
- GGCLNOIGPMGLDB-GYKMGIIDSA-N cholest-5-en-3-one Chemical compound C1C=C2CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 GGCLNOIGPMGLDB-GYKMGIIDSA-N 0.000 title description 2
- NYOXRYYXRWJDKP-UHFFFAOYSA-N cholestenone Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 NYOXRYYXRWJDKP-UHFFFAOYSA-N 0.000 title description 2
- 241000187654 Nocardia Species 0.000 claims description 9
- 241001251094 Formica Species 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000003647 oxidation Effects 0.000 claims description 2
- 238000007254 oxidation reaction Methods 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims 1
- 229930182558 Sterol Natural products 0.000 description 20
- 150000003432 sterols Chemical class 0.000 description 20
- 235000003702 sterols Nutrition 0.000 description 20
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 13
- 239000000839 emulsion Substances 0.000 description 12
- KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 10
- CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 10
- KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 10
- LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 10
- ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 10
- MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 10
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 10
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 10
- 235000015500 sitosterol Nutrition 0.000 description 10
- 229950005143 sitosterol Drugs 0.000 description 10
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 10
- 229940041514 candida albicans extract Drugs 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 239000012138 yeast extract Substances 0.000 description 7
- 239000001888 Peptone Substances 0.000 description 6
- 108010080698 Peptones Proteins 0.000 description 6
- 235000019319 peptone Nutrition 0.000 description 6
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 4
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 4
- 230000003698 anagen phase Effects 0.000 description 4
- 229910052799 carbon Inorganic materials 0.000 description 4
- 230000006698 induction Effects 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 4
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 4
- 238000001238 wet grinding Methods 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 3
- QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 235000016831 stigmasterol Nutrition 0.000 description 3
- 229940032091 stigmasterol Drugs 0.000 description 3
- QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 239000007900 aqueous suspension Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000001110 calcium chloride Substances 0.000 description 2
- 229910001628 calcium chloride Inorganic materials 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- FBAFATDZDUQKNH-UHFFFAOYSA-M iron chloride Chemical compound [Cl-].[Fe] FBAFATDZDUQKNH-UHFFFAOYSA-M 0.000 description 2
- 229940061634 magnesium sulfate heptahydrate Drugs 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- CVULGJIRGZVJHQ-UHFFFAOYSA-N 2-ethylbenzothiazole Chemical compound C1=CC=C2SC(CC)=NC2=C1 CVULGJIRGZVJHQ-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- NLDBCFRIELDMRO-UHFFFAOYSA-N Stigmasterin Natural products CCCC(CC)C=CC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C NLDBCFRIELDMRO-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- KZJWDPNRJALLNS-FBZNIEFRSA-N clionasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-FBZNIEFRSA-N 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- WRUGWIBCXHJTDG-UHFFFAOYSA-L magnesium sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Mg+2].[O-]S([O-])(=O)=O WRUGWIBCXHJTDG-UHFFFAOYSA-L 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2456586A DE2456586C3 (de) | 1974-11-29 | 1974-11-29 | Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiert |
| IT27598/75A IT1049600B (it) | 1974-11-29 | 1975-09-24 | Impiego di certi ceppi di microorganismi per l ottenimento di cole sterinossidase che ossida la cole sterina con 02 a colestenone piu h2 o2 |
| IL48195A IL48195A (en) | 1974-11-29 | 1975-09-28 | Process for obtaining cholesterol oxidase |
| GB4533775A GB1473777A (en) | 1974-11-29 | 1975-10-31 | Process for obtaining cholesterol oxidase |
| FR7535381A FR2292766A2 (fr) | 1974-11-29 | 1975-11-19 | Utilisation de souches de micro-organismes determinees pour la preparation de cholesterol-oxydase, capable d'oxyder le cholesterol a l'aide d'oxygene en cholestenone et eau oxygenee |
| US05/633,997 US4008127A (en) | 1974-11-29 | 1975-11-20 | Process for the preparation of cholesterol oxidase |
| JP50141008A JPS5182785A (enExample) | 1974-11-29 | 1975-11-25 | |
| ZA00757492A ZA757492B (en) | 1974-11-29 | 1975-11-28 | Improvements relating to the production of cholesterinoxydase |
| JP15024680A JPS5678587A (en) | 1974-11-29 | 1980-10-28 | Production of cholesterine oxydase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2456586A DE2456586C3 (de) | 1974-11-29 | 1974-11-29 | Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiert |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2456586A1 DE2456586A1 (de) | 1976-06-16 |
| DE2456586B2 DE2456586B2 (de) | 1978-12-14 |
| DE2456586C3 true DE2456586C3 (de) | 1979-09-27 |
Family
ID=5932115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2456586A Expired DE2456586C3 (de) | 1974-11-29 | 1974-11-29 | Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiert |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4008127A (enExample) |
| JP (2) | JPS5182785A (enExample) |
| DE (1) | DE2456586C3 (enExample) |
| FR (1) | FR2292766A2 (enExample) |
| GB (1) | GB1473777A (enExample) |
| IL (1) | IL48195A (enExample) |
| IT (1) | IT1049600B (enExample) |
| ZA (1) | ZA757492B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS527484A (en) * | 1975-07-04 | 1977-01-20 | Kikkoman Corp | Process for preparing cholesterol oxidase |
| CA1067844A (en) * | 1975-12-11 | 1979-12-11 | Eastman Kodak Company | Method and medium for producing cholesterol oxidase |
| US5340539A (en) * | 1989-03-16 | 1994-08-23 | Chemtrak, Inc. | Non-instrumented cholesterol assay |
| US5238816A (en) * | 1989-07-24 | 1993-08-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Omega carboxyalcohol oxidase enzyme |
| JP2786679B2 (ja) * | 1989-07-24 | 1998-08-13 | 旭化成工業株式会社 | 新規なω位カルボキシアルコール酸化酵素 |
| US5206148A (en) * | 1989-07-24 | 1993-04-27 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for assaying aliphatic alcohol, aliphatic aldehyde or ω-carboxylic acid derivatives thereof |
| US11759914B2 (en) | 2020-08-06 | 2023-09-19 | Mate Precision Technologies Inc. | Vise assembly |
| WO2022032148A1 (en) | 2020-08-06 | 2022-02-10 | Mate Precision Technologies Inc. | Tooling base assembly |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1385319A (en) * | 1971-09-22 | 1975-02-26 | Nat Res Dev | Enzyme preparations |
| DE2224133B2 (de) | 1972-05-17 | 1974-06-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von bestimmten Mikroorganismen-Stämmen zur Gewinnung von Cholesterinoxydase, welche Cholesterin mit O tief 2 zu Cholestenon + H tief 2 O tief 2 oxydiert |
| DE2264646A1 (de) * | 1972-05-17 | 1974-07-18 | Boehringer Mannheim Gmbh | Gewinnung von cholesterinoxydase |
| US3909359A (en) * | 1974-03-25 | 1975-09-30 | Eastman Kodak Co | Method for the preparation of cholesterol oxidase |
-
1974
- 1974-11-29 DE DE2456586A patent/DE2456586C3/de not_active Expired
-
1975
- 1975-09-24 IT IT27598/75A patent/IT1049600B/it active
- 1975-09-28 IL IL48195A patent/IL48195A/xx unknown
- 1975-10-31 GB GB4533775A patent/GB1473777A/en not_active Expired
- 1975-11-19 FR FR7535381A patent/FR2292766A2/fr active Granted
- 1975-11-20 US US05/633,997 patent/US4008127A/en not_active Expired - Lifetime
- 1975-11-25 JP JP50141008A patent/JPS5182785A/ja active Pending
- 1975-11-28 ZA ZA00757492A patent/ZA757492B/xx unknown
-
1980
- 1980-10-28 JP JP15024680A patent/JPS5678587A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2456586B2 (de) | 1978-12-14 |
| FR2292766B2 (enExample) | 1979-02-02 |
| JPS5678587A (en) | 1981-06-27 |
| IL48195A (en) | 1979-03-12 |
| GB1473777A (en) | 1977-05-18 |
| FR2292766A2 (fr) | 1976-06-25 |
| IT1049600B (it) | 1981-02-10 |
| IL48195A0 (en) | 1975-11-25 |
| ZA757492B (en) | 1976-12-29 |
| US4008127A (en) | 1977-02-15 |
| JPS5182785A (enExample) | 1976-07-20 |
| JPS5744318B2 (enExample) | 1982-09-20 |
| DE2456586A1 (de) | 1976-06-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69132370T2 (de) | Methode zur herstellung von eicosapentansäuren | |
| DE2224133A1 (de) | Gewinnung von cholesterinoxydase | |
| DE2524355A1 (de) | Physiologisch aktive verbindungen und verfahren zu ihrer herstellung | |
| DE2456586C3 (de) | Verwendung von bestimmten Mikroorganismenstämmen zur Gewinnung von Cholesterinoxidase, welche Cholesterin mit O2 zu Cholestenon + H2 O2 oxidiert | |
| DE3343551A1 (de) | Verfahren zur biotechnologischen herstellung von poly-d(-)-3-hydroxybuttersaeure | |
| DE2021465C3 (de) | Verfahren zur Herstellung eines Enzympräparates, welches die OH-Gruppe in der ibeta-Stellung des Cholesterin« dehydriert | |
| EP0170880A1 (de) | Verfahren zur Herstellung von Aminooxydase enthaltendem Material, bzw. Aminooxydase, aus Mikroorganismen, solche Produkte und deren Verwendung zum Abbau von Histamin in Nahrungsmitteln, Getränken und Futtermitteln | |
| DE2035814C3 (de) | Pleuromutilin-Derivate, Verfahren zu ihrer Herstellung und Verwendung | |
| DE1692313B2 (de) | Verfahren zum herstellen von dickgelegten, gesaeuerten milchprodukten | |
| DE2633451C3 (de) | Herstellung von Bakterienzellmasse | |
| DE2150593A1 (de) | Neues Antibiotikum WS-4545 und dessen Derivate | |
| DE69520829T2 (de) | Herstellung von L - Ascorbinsäure in Mikroorganismen | |
| DE69009568T2 (de) | Mikrobiologisches Verfahren zur Herstellung von Methylketonen. | |
| DE2344006C3 (de) | Verfahren zur biotechnischen behandlung von epsilon-caprolactam enthaltenden abwaessern | |
| CH664767A5 (de) | Verfahren zur herstellung von 2-(substituiertphenyl)-propionsaeure durch mikroorganismen. | |
| DE3877685T2 (de) | Verfahren zur herstellung von d(-)-tartarsaeure. | |
| DE2264646A1 (de) | Gewinnung von cholesterinoxydase | |
| DE2849393C2 (de) | Verfahren zur biotechnischen Herstellung von 2,5-Diketogluconsäure | |
| DE730908C (de) | Verfahren zur Darstellung von ungesaettigten Ketonen der Cyclopentanopolyhydrophenanthrenreihe auf biochemischem Wege | |
| AT337131B (de) | Verfahren zur erzeugung von glucose isomerisierendem enzym | |
| DD259969A3 (de) | Verfahren zur herstellung von gluconsaeure mittels bakterien | |
| DE3051206C2 (de) | Verfahren zur fermentativen Herstellung von Monacolin K | |
| DE2630680A1 (de) | Verfahren zur behandlung der destillationsrueckstaende von weissweinen | |
| DE1642648C3 (de) | Verfahren zur Herstellung einer konzentriert Propionibacterium shermanii enthaltenden Zellpaste | |
| DE1517133C3 (de) | Verfahren zur Herstellung eines Käsearomatisierungsmlttels |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) |