DE2428415A1 - 1,4-dihydropyridine, verfahren zu ihrer herstellung und arzneimittel - Google Patents

1,4-dihydropyridine, verfahren zu ihrer herstellung und arzneimittel

Info

Publication number
DE2428415A1
DE2428415A1 DE19742428415 DE2428415A DE2428415A1 DE 2428415 A1 DE2428415 A1 DE 2428415A1 DE 19742428415 DE19742428415 DE 19742428415 DE 2428415 A DE2428415 A DE 2428415A DE 2428415 A1 DE2428415 A1 DE 2428415A1
Authority
DE
Germany
Prior art keywords
ester
trifluoromethylphenyl
dihydro
group
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19742428415
Other languages
German (de)
English (en)
Inventor
@@ Loev Bernard
Anthony Maitland Roe
Robert Antony Slater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of DE2428415A1 publication Critical patent/DE2428415A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
DE19742428415 1973-06-12 1974-06-12 1,4-dihydropyridine, verfahren zu ihrer herstellung und arzneimittel Withdrawn DE2428415A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2779373A GB1425729A (en) 1973-06-12 1973-06-12 1,4-dihydropyridine compounds

Publications (1)

Publication Number Publication Date
DE2428415A1 true DE2428415A1 (de) 1975-01-09

Family

ID=10265398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19742428415 Withdrawn DE2428415A1 (de) 1973-06-12 1974-06-12 1,4-dihydropyridine, verfahren zu ihrer herstellung und arzneimittel

Country Status (11)

Country Link
US (1) US3910937A (https=)
JP (1) JPS5035173A (https=)
AU (1) AU475890B2 (https=)
BE (1) BE816157A (https=)
CA (1) CA1016177A (https=)
DE (1) DE2428415A1 (https=)
FR (1) FR2233052B1 (https=)
GB (1) GB1425729A (https=)
HU (1) HU167965B (https=)
IL (1) IL44933A0 (https=)
NL (1) NL7407837A (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330470A3 (en) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. 1,4-dihydropyridine derivatives useful against tumour cells
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0657432B1 (de) * 1993-12-10 2003-03-12 Bayer Ag Phenyl-substituierte 1,4-Dihydropyridine mit cerebraler Aktivität

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330470A3 (en) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. 1,4-dihydropyridine derivatives useful against tumour cells
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells

Also Published As

Publication number Publication date
FR2233052A1 (https=) 1975-01-10
US3910937A (en) 1975-10-07
BE816157A (fr) 1974-12-11
AU6962074A (en) 1975-12-04
FR2233052B1 (https=) 1978-07-28
GB1425729A (en) 1976-02-18
HU167965B (https=) 1976-01-28
IL44933A0 (en) 1974-07-31
JPS5035173A (https=) 1975-04-03
AU475890B2 (en) 1976-09-09
NL7407837A (https=) 1974-12-16
CA1016177A (en) 1977-08-23

Similar Documents

Publication Publication Date Title
EP0002208B1 (de) Nitrosubstituierte 1,4-Dihydropyridine, diese enthaltende Arzneimittel sowie deren Herstellung
EP0012180B1 (de) Neue 1,4-Dihydropyridinverbindungen, Verfahren zu ihrer Herstellung, die genannten Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
CH637938A5 (de) Verfahren zur herstellung neuer 1,4-dihydropyridinderivate.
DE2210633C2 (de) Kondensierte Pyridinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2756226A1 (de) 1,4-dihydropyridin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE2841667A1 (de) Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0039863B1 (de) 1,4-Dihydropyridine mit unterschiedlichen Substituenten in 2- und 6-Position, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
DE1645903C3 (de) Verfahren zur Herstellung von 3 Halogen-3H-1,2-dihydro-1,4-benzodiazepin-2-on-derivaten
DE2141616C3 (de) Oxazole- und Oxazine eckige Klammer auf 3,2-c eckige Klammer zu chinazolinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2659665A1 (de) Neue 1,4-dihydropyridin-derivate
DE2428415A1 (de) 1,4-dihydropyridine, verfahren zu ihrer herstellung und arzneimittel
WO1997040032A1 (de) Chirale phenyldihydrofuranone als pde-iv inhibitoren
DE2549568C3 (de) 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DD284024A5 (de) Verfahren zum herstellen von o hoch 2 tief ,2'-anhydro-1-(beta-d-arabinofuranosyl)thymin
EP0009465A1 (de) N-(1-(4-Amino-2-chinazolinyl)-3- oder -4-piperidyl-lactame, Verfahren zu ihrer Herstellung, sowie pharmazeutische Präparate enthaltend diese Verbindungen
EP0385287A2 (de) Verfahren zur Herstellung von D-Mannosaminderivaten
DE3217236A1 (de) 5,6-dihydro-11h-dibenzo (b,e)- azepin-6-one, verfahren zu ihrer herstellung, sowie diese enthaltende arzneimittel
DE960813C (de) Verfahren zur Herstellung von ungesaettigten ª†- und ª€-Laktonen
DE2530005C3 (de) 6,11-Dihydrodibenzo [b,e] thiepin-Derivate und deren Salze, Verfahren zu ihrer Herstellung und diese Substanzen enthaltende pharmazeutische Zubereitungen
DE2446495A1 (de) Neue pyrazolo(3,4-b)thieno(2,3-d) pyridin-2-carboxylsaeuren und -saeureester
DE2551235B2 (de) Aryloxyalkylpiperidine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
EP0042566B1 (de) 4,4-Disubstituierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung sowie ihre Verwendung in Arzneimitteln
DE2140601A1 (de) Derivate von Thiazolino Pyrin idinon und Verfahren zu deren Herstellung
DE3048318A1 (de) 4-alkoxyalkyl substituierte (beta)-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AT368493B (de) Verfahren zur herstellung von neuen nitrosubstituierten 1,4-dihydropyridinen

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee