DE2423811A1 - Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat - Google Patents

Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat

Info

Publication number
DE2423811A1
DE2423811A1 DE2423811A DE2423811A DE2423811A1 DE 2423811 A1 DE2423811 A1 DE 2423811A1 DE 2423811 A DE2423811 A DE 2423811A DE 2423811 A DE2423811 A DE 2423811A DE 2423811 A1 DE2423811 A1 DE 2423811A1
Authority
DE
Germany
Prior art keywords
weight
freeze
dried
preparations
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2423811A
Other languages
German (de)
English (en)
Inventor
Yasuo Araki
Kenji Hikawa
Yoshitaka Ikezuki
Yoshikatsu Koide
Tokuro Nakamura
Emiko Ono
Oita Saiki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kohjin Co
Original Assignee
Kohjin Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kohjin Co filed Critical Kohjin Co
Publication of DE2423811A1 publication Critical patent/DE2423811A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE2423811A 1973-05-17 1974-05-16 Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat Pending DE2423811A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5414573A JPS5637967B2 (sv) 1973-05-17 1973-05-17

Publications (1)

Publication Number Publication Date
DE2423811A1 true DE2423811A1 (de) 1974-12-05

Family

ID=12962379

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2423811A Pending DE2423811A1 (de) 1973-05-17 1974-05-16 Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat

Country Status (4)

Country Link
JP (1) JPS5637967B2 (sv)
DE (1) DE2423811A1 (sv)
ES (1) ES426414A1 (sv)
FR (1) FR2229416A1 (sv)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658406A1 (de) * 1975-12-31 1977-07-07 Asahi Chemical Ind Arzneimittelzubereitungen mit verbesserter loeslichkeit und ihre herstellung
WO1998029100A1 (en) * 1996-12-31 1998-07-09 Korea Institute Of Science And Technology Method of manufacturing porous matrix-type controlled release systems using emulsion technique
WO1999002542A1 (en) * 1997-07-11 1999-01-21 Astra Pharmaceuticals Ltd. New formulation
US6114313A (en) * 1996-12-20 2000-09-05 Astra Zeneca Uk Limited Pharmaceutical compositions for freeze drying

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51139613A (en) * 1975-05-24 1976-12-02 Nippon Shinyaku Co Ltd An absorbable non-crystalline sterol glycoside monopalmitate ester and a method for preparing its pharmaceutical
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
CA2280130C (en) * 1997-02-05 2007-12-18 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing sphingoglycolipid and process for preparing them
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658406A1 (de) * 1975-12-31 1977-07-07 Asahi Chemical Ind Arzneimittelzubereitungen mit verbesserter loeslichkeit und ihre herstellung
US6114313A (en) * 1996-12-20 2000-09-05 Astra Zeneca Uk Limited Pharmaceutical compositions for freeze drying
WO1998029100A1 (en) * 1996-12-31 1998-07-09 Korea Institute Of Science And Technology Method of manufacturing porous matrix-type controlled release systems using emulsion technique
GB2336110A (en) * 1996-12-31 1999-10-13 Korea Inst Sci & Tech Method of manufacturing porous matrix-type controlled release systems using emulsion technique
GB2336110B (en) * 1996-12-31 2000-10-18 Korea Inst Sci & Tech Method of manufacturing porous matrix-type controlled release systems using emulsion technique
WO1999002542A1 (en) * 1997-07-11 1999-01-21 Astra Pharmaceuticals Ltd. New formulation
US6130208A (en) * 1997-07-11 2000-10-10 Astrazeneca Uk Limited Formulation containing a nucleotide analogue
CZ298110B6 (cs) * 1997-07-11 2007-06-27 Astrazeneca Uk Limited Lyofilizovaná, ve spreji susená nebo vakuove susená farmaceutická kompozice a zpusob její výroby

Also Published As

Publication number Publication date
ES426414A1 (es) 1976-07-01
JPS505523A (sv) 1975-01-21
FR2229416A1 (en) 1974-12-13
JPS5637967B2 (sv) 1981-09-03

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