DE2362695A1 - Neue 2,7-bis basische vinylenderivate von xanthen und thioxanthen, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische zusammensetzungen - Google Patents
Neue 2,7-bis basische vinylenderivate von xanthen und thioxanthen, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische zusammensetzungenInfo
- Publication number
- DE2362695A1 DE2362695A1 DE2362695A DE2362695A DE2362695A1 DE 2362695 A1 DE2362695 A1 DE 2362695A1 DE 2362695 A DE2362695 A DE 2362695A DE 2362695 A DE2362695 A DE 2362695A DE 2362695 A1 DE2362695 A1 DE 2362695A1
- Authority
- DE
- Germany
- Prior art keywords
- bis
- xanthene
- thioxanthene
- basic
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 title claims description 22
- 238000000034 method Methods 0.000 title claims description 10
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- 239000008194 pharmaceutical composition Substances 0.000 title description 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical class C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims description 40
- 241000700605 Viruses Species 0.000 claims description 29
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims description 14
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 claims description 14
- 125000004432 carbon atom Chemical group C* 0.000 claims description 13
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 12
- 150000003839 salts Chemical class 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 9
- 125000000217 alkyl group Chemical group 0.000 claims description 8
- 125000002947 alkylene group Chemical group 0.000 claims description 8
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- 125000004434 sulfur atom Chemical group 0.000 claims description 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims description 2
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- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 6
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 5
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- 239000012279 sodium borohydride Substances 0.000 description 4
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- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
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- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00317128A US3817992A (en) | 1972-12-21 | 1972-12-21 | Xanthene and thioxanthene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2362695A1 true DE2362695A1 (de) | 1974-06-27 |
Family
ID=23232235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2362695A Withdrawn DE2362695A1 (de) | 1972-12-21 | 1973-12-17 | Neue 2,7-bis basische vinylenderivate von xanthen und thioxanthen, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische zusammensetzungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3817992A (enrdf_load_stackoverflow) |
| JP (1) | JPS4988874A (enrdf_load_stackoverflow) |
| AU (1) | AU476380B2 (enrdf_load_stackoverflow) |
| CA (1) | CA1018973A (enrdf_load_stackoverflow) |
| DE (1) | DE2362695A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2211233B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1416749A (enrdf_load_stackoverflow) |
| IL (1) | IL43665A (enrdf_load_stackoverflow) |
| ZA (1) | ZA738215B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03006372A (es) * | 2001-01-16 | 2004-04-20 | Guilford Pharm Inc | Compuestos aromaticos simetricamente disustituidos y composiciones farmaceuticas para inhibir poli (adp-ribosa) glicohidrolasa y metodos para su uso. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3859286A (en) * | 1970-12-11 | 1975-01-07 | Richardson Merrell Inc | Bis-basic ketones of xanthene and xanthen-9-one |
| US3856789A (en) * | 1971-04-23 | 1974-12-24 | Richardson Merrell Inc | Bis-basic ketones of thioxanthene |
-
1972
- 1972-12-21 US US00317128A patent/US3817992A/en not_active Expired - Lifetime
-
1973
- 1973-10-23 ZA ZA738215*A patent/ZA738215B/xx unknown
- 1973-10-26 AU AU61884/73A patent/AU476380B2/en not_active Expired
- 1973-10-29 CA CA184,442A patent/CA1018973A/en not_active Expired
- 1973-11-21 IL IL43665A patent/IL43665A/en unknown
- 1973-12-17 DE DE2362695A patent/DE2362695A1/de not_active Withdrawn
- 1973-12-17 GB GB5825873A patent/GB1416749A/en not_active Expired
- 1973-12-19 FR FR7345509A patent/FR2211233B1/fr not_active Expired
- 1973-12-20 JP JP48141917A patent/JPS4988874A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB1416749A (en) | 1975-12-03 |
| FR2211233A1 (enrdf_load_stackoverflow) | 1974-07-19 |
| US3817992A (en) | 1974-06-18 |
| CA1018973A (en) | 1977-10-11 |
| AU476380B2 (en) | 1976-09-16 |
| IL43665A0 (en) | 1974-03-14 |
| ZA738215B (en) | 1974-08-28 |
| AU6188473A (en) | 1975-05-01 |
| JPS4988874A (enrdf_load_stackoverflow) | 1974-08-24 |
| IL43665A (en) | 1977-05-31 |
| FR2211233B1 (enrdf_load_stackoverflow) | 1977-01-28 |
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