DE2345068C2 - Verfahren zur Herstellung von Indolo[2,3-a]chinolizinen - Google Patents

Verfahren zur Herstellung von Indolo[2,3-a]chinolizinen

Info

Publication number
DE2345068C2
DE2345068C2 DE19732345068 DE2345068A DE2345068C2 DE 2345068 C2 DE2345068 C2 DE 2345068C2 DE 19732345068 DE19732345068 DE 19732345068 DE 2345068 A DE2345068 A DE 2345068A DE 2345068 C2 DE2345068 C2 DE 2345068C2
Authority
DE
Germany
Prior art keywords
general formula
reaction mixture
acid
ethyl
reacts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19732345068
Other languages
German (de)
English (en)
Other versions
DE2345068A1 (de
Inventor
György Dipl.-Chem. Dr. Kalaus
Tibor Dipl.-Chem. Dr. Keve
János Dipl.-Chem. Dr. Kreidl
István Dipl.-Chem. Polgár
Béla Dipl.-Chem. Stefkó
Lajos Dipl.-Chem. Dr. Szabó
Csaba Dipl.-Chem. Dr. Szántay
Péter Dipl.-Chem. Budapest Turcsányi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of DE2345068A1 publication Critical patent/DE2345068A1/de
Application granted granted Critical
Publication of DE2345068C2 publication Critical patent/DE2345068C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19732345068 1972-09-06 1973-09-06 Verfahren zur Herstellung von Indolo[2,3-a]chinolizinen Expired DE2345068C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI000485 HU167366B (ja) 1972-09-06 1972-09-06

Publications (2)

Publication Number Publication Date
DE2345068A1 DE2345068A1 (de) 1974-03-14
DE2345068C2 true DE2345068C2 (de) 1986-06-05

Family

ID=11000906

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732345068 Expired DE2345068C2 (de) 1972-09-06 1973-09-06 Verfahren zur Herstellung von Indolo[2,3-a]chinolizinen

Country Status (13)

Country Link
JP (1) JPS5221517B2 (ja)
AT (1) AT327908B (ja)
BE (1) BE804495A (ja)
CS (1) CS175358B2 (ja)
DD (1) DD107281A5 (ja)
DE (1) DE2345068C2 (ja)
DK (1) DK140761B (ja)
FR (1) FR2197873B1 (ja)
GB (1) GB1401579A (ja)
HU (1) HU167366B (ja)
NL (1) NL180421C (ja)
SU (1) SU535909A3 (ja)
YU (1) YU36954B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
JPH0414224Y2 (ja) * 1987-04-21 1992-03-31
HU207070B (en) * 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
US7947253B2 (en) * 2004-01-15 2011-05-24 Aposense Ltd. Perturbed membrane-binding compounds and methods of using the same
US7270799B2 (en) * 2004-01-15 2007-09-18 Nst Neurosurvival Technologies Ltd. Perturbed membrane-binding compounds and methods of using the same
EP2730604B1 (en) 2006-03-21 2018-10-24 The Governors of the University of Alberta Functionalized caprolactone monomers useful for making poly(ethylene oxide)-block-poly(ester) block copolymers
CN103626651B (zh) * 2012-08-27 2015-07-22 东北制药集团股份有限公司 一种制备合成长春西汀中间体γ-羟丙基-乙基丙二酸的方法
CN108047224A (zh) * 2017-11-24 2018-05-18 东北制药集团股份有限公司 一种制备烯胺高氯酸盐的方法

Also Published As

Publication number Publication date
FR2197873B1 (ja) 1982-04-02
JPS5221517B2 (ja) 1977-06-10
JPS5040597A (ja) 1975-04-14
YU36954B (en) 1984-08-31
YU238173A (en) 1982-02-25
DK140761C (ja) 1980-04-14
NL7312084A (ja) 1974-03-08
GB1401579A (en) 1975-07-16
CS175358B2 (ja) 1977-05-31
DD107281A5 (ja) 1974-07-20
BE804495A (fr) 1974-01-02
NL180421C (nl) 1987-02-16
AT327908B (de) 1976-02-25
SU535909A3 (ru) 1976-11-15
ATA746473A (de) 1975-05-15
HU167366B (ja) 1975-09-27
DE2345068A1 (de) 1974-03-14
FR2197873A1 (ja) 1974-03-29
DK140761B (da) 1979-11-12

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: KINZEBACH, W., DIPL.-CHEM. DR.PHIL. RIEDL, P., DIP

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee