DE2335466A1 - Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel - Google Patents

Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Info

Publication number
DE2335466A1
DE2335466A1 DE19732335466 DE2335466A DE2335466A1 DE 2335466 A1 DE2335466 A1 DE 2335466A1 DE 19732335466 DE19732335466 DE 19732335466 DE 2335466 A DE2335466 A DE 2335466A DE 2335466 A1 DE2335466 A1 DE 2335466A1
Authority
DE
Germany
Prior art keywords
alkyl
formula
ester
salts
given above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19732335466
Other languages
German (de)
English (en)
Inventor
Friedrich Dr Bossert
Kurt Dr Stoepel
Wulf Dr Vater
Egbert Dr Wehinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19732335466 priority Critical patent/DE2335466A1/de
Priority to CA204,204A priority patent/CA1025450A/en
Priority to AU70969/74A priority patent/AU477107B2/en
Priority to PL1974172611A priority patent/PL94266B1/pl
Priority to LU70498A priority patent/LU70498A1/xx
Priority to FI2120/74A priority patent/FI212074A/fi
Priority to NL7409344A priority patent/NL7409344A/xx
Priority to PL1974183228A priority patent/PL91873B1/pl
Priority to JP49078370A priority patent/JPS6011030B2/ja
Priority to DD179837A priority patent/DD118631A5/xx
Priority to IL45233A priority patent/IL45233A/xx
Priority to AT569674A priority patent/AT337699B/de
Priority to ZA00744461A priority patent/ZA744461B/xx
Priority to ES428185A priority patent/ES428185A1/es
Priority to BE146464A priority patent/BE817540A/xx
Priority to SE7409146A priority patent/SE7409146L/xx
Priority to CH960374A priority patent/CH614196A5/xx
Priority to IE1466/74A priority patent/IE39602B1/xx
Priority to GB3074674A priority patent/GB1436289A/en
Priority to HU74BA00003114A priority patent/HU171401B/hu
Priority to DK373974A priority patent/DK373974A/da
Priority to FR7424425A priority patent/FR2236497B1/fr
Publication of DE2335466A1 publication Critical patent/DE2335466A1/de
Priority to US05/576,724 priority patent/US3974278A/en
Priority to ES448396A priority patent/ES448396A1/es
Priority to ES448395A priority patent/ES448395A1/es
Priority to US05/585,963 priority patent/US4020178A/en
Priority to US05/609,153 priority patent/US3971796A/en
Priority to ES448397A priority patent/ES448397A1/es
Priority to ES448394A priority patent/ES448394A1/es
Priority to CH1241077A priority patent/CH622507A5/de
Priority to JP57000455A priority patent/JPS5943952B2/ja
Priority to JP57000454A priority patent/JPS5943951B2/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE19732335466 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel Withdrawn DE2335466A1 (de)

Priority Applications (32)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
CA204,204A CA1025450A (en) 1973-07-12 1974-07-05 1,4-dihydropyridine esters
AU70969/74A AU477107B2 (en) 1973-07-12 1974-07-08 New alkoxyalkyl-1. 4-dihydropyridines their preparation, and their medicinal use
PL1974172611A PL94266B1 (pl) 1973-07-12 1974-07-10
LU70498A LU70498A1 (pl) 1973-07-12 1974-07-10
FI2120/74A FI212074A (pl) 1973-07-12 1974-07-10
NL7409344A NL7409344A (nl) 1973-07-12 1974-07-10 Werkwijze voor het bereiden van alkoxyalkyl 1.4-dihydropyridinen, alsmede de toepassing daarvan als farmaceutische preparaten.
PL1974183228A PL91873B1 (pl) 1973-07-12 1974-07-10
JP49078370A JPS6011030B2 (ja) 1973-07-12 1974-07-10 アルコキシアルキル１，４−ジヒドロピリジンエステルまたはその塩の製造方法
DD179837A DD118631A5 (pl) 1973-07-12 1974-07-10
IL45233A IL45233A (en) 1973-07-12 1974-07-10 Alkoxyalkyl-1,4-dihydropyridine-3,5-dicarboxylic acid diester derivatives,their preparation and pharmaceutical compositions containing them
AT569674A AT337699B (de) 1973-07-12 1974-07-10 Verfahren zur herstellung von neuen alkoxyalkyl-1,4-dihydropyridinestern und ihren salzen
BE146464A BE817540A (fr) 1973-07-12 1974-07-11 Nouveaux esters d'alkoxyalkyl-1
DK373974A DK373974A (pl) 1973-07-12 1974-07-11
ES428185A ES428185A1 (es) 1973-07-12 1974-07-11 Procedimiento para la obtencion de esteres de alcoxialquil-hidropiridinas.
ZA00744461A ZA744461B (en) 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use
SE7409146A SE7409146L (sv) 1973-07-12 1974-07-11 Alkoxialkyl-1,4-dihydropyridiner till anvendning som lekemedel och sett for deras framstellning.
CH960374A CH614196A5 (en) 1973-07-12 1974-07-11 Process for the preparation of alkoxyalkyl-1,4-dihydropyridines
IE1466/74A IE39602B1 (en) 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation, and their medicinal use
GB3074674A GB1436289A (en) 1973-07-12 1974-07-11 Alkoxyalkyl-1,4-dihydropyridines their preparation and their medicinal use
HU74BA00003114A HU171401B (hu) 1973-07-12 1974-07-11 Sposob poluchenija proizvodnykh 2-alkoksial'kil-1,4-digidropiridina
FR7424425A FR2236497B1 (pl) 1973-07-12 1974-07-12
US05/576,724 US3974278A (en) 1973-07-12 1975-05-12 1,4-Dihydropyridine esters
ES448396A ES448396A1 (es) 1973-07-12 1975-05-31 Procedimiento para la obtencion de esteres de alcoxialquil- hidropiridinas.
ES448395A ES448395A1 (es) 1973-07-12 1975-05-31 Procedimiento para la obtencion de esteres de alcoxialquil- hidropiridinas.
US05/585,963 US4020178A (en) 1973-07-12 1975-06-11 1,4-Dihydropyridine esters used as coronary dilators and anti-hypertensives
US05/609,153 US3971796A (en) 1973-07-12 1975-08-29 1,4-Dihydropyridine esters
ES448397A ES448397A1 (es) 1973-07-12 1976-05-31 Procedimiento para la obtencion de esteres de alcoxialquil- hidropiridinas.
ES448394A ES448394A1 (es) 1973-07-12 1976-05-31 Procedimiento para la obtencion de esteres de alcoxialquil- hidropiridina.
CH1241077A CH622507A5 (en) 1973-07-12 1977-10-11 Process for the preparation of 1,4-dihydropyridines
JP57000455A JPS5943952B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造方法
JP57000454A JPS5943951B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DE2335466A1 true DE2335466A1 (de) 1975-01-30

Family

ID=5886689

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732335466 Withdrawn DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Country Status (21)

Country Link
JP (3) JPS6011030B2 (pl)
AT (1) AT337699B (pl)
AU (1) AU477107B2 (pl)
BE (1) BE817540A (pl)
CA (1) CA1025450A (pl)
CH (2) CH614196A5 (pl)
DD (1) DD118631A5 (pl)
DE (1) DE2335466A1 (pl)
DK (1) DK373974A (pl)
ES (5) ES428185A1 (pl)
FI (1) FI212074A (pl)
FR (1) FR2236497B1 (pl)
GB (1) GB1436289A (pl)
HU (1) HU171401B (pl)
IE (1) IE39602B1 (pl)
IL (1) IL45233A (pl)
LU (1) LU70498A1 (pl)
NL (1) NL7409344A (pl)
PL (2) PL94266B1 (pl)
SE (1) SE7409146L (pl)
ZA (1) ZA744461B (pl)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756226A1 (de) * 1976-12-17 1978-06-29 Fujisawa Pharmaceutical Co 1,4-dihydropyridin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
EP0124742A2 (de) * 1983-04-05 1984-11-14 Bayer Ag Verfahren zur Herstellung von symmetrischen 1,4-Dihydropyridindicarbonsäureestern
EP0124743A2 (de) * 1983-04-05 1984-11-14 Bayer Ag Verfahren zur Herstellung von unsymmetrischen 1,4-Di-hydropyridindicarbonsäureestern
EP0173943A1 (de) * 1984-09-05 1986-03-12 Bayer Ag Neue Pyridylethyl-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
WO1986002836A1 (en) * 1984-11-12 1986-05-22 Sandoz Ag New use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.
AT395586B (de) * 1988-03-08 1993-01-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399873B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399872B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT400241B (de) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
JPS53146941U (pl) * 1977-04-26 1978-11-18
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
CA1267416A (en) 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (ja) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル 車両の台数検出装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756226A1 (de) * 1976-12-17 1978-06-29 Fujisawa Pharmaceutical Co 1,4-dihydropyridin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
EP0124743A3 (en) * 1983-04-05 1987-05-20 Bayer Ag Process for the preparation of asymmetric 1,4-dihydropyridine-carboxylic acid esters
EP0124742A2 (de) * 1983-04-05 1984-11-14 Bayer Ag Verfahren zur Herstellung von symmetrischen 1,4-Dihydropyridindicarbonsäureestern
EP0124743A2 (de) * 1983-04-05 1984-11-14 Bayer Ag Verfahren zur Herstellung von unsymmetrischen 1,4-Di-hydropyridindicarbonsäureestern
EP0124742A3 (en) * 1983-04-05 1987-05-27 Bayer Ag Process for the preparation of symmetric 1,4-dihydropyridine-carboxylic esters
EP0173943A1 (de) * 1984-09-05 1986-03-12 Bayer Ag Neue Pyridylethyl-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
WO1986002836A1 (en) * 1984-11-12 1986-05-22 Sandoz Ag New use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
AT395586B (de) * 1988-03-08 1993-01-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399873B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399872B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT400241B (de) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.
EP0500426A1 (fr) * 1991-02-20 1992-08-26 Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. Dérivés de 2,6-diméthyl-4-(4'-hydroxy-3',5'-di-t-butylphényl)-1,4-dihydropyridine, leur procédé de préparation et leur utilisation comme capteurs de radicaux libres

Also Published As

Publication number Publication date
FR2236497B1 (pl) 1978-07-21
ES448396A1 (es) 1977-09-16
IL45233A (en) 1978-06-15
IL45233A0 (en) 1974-10-22
ZA744461B (en) 1975-07-30
ES448395A1 (es) 1977-09-16
FI212074A (pl) 1975-01-13
PL91873B1 (pl) 1977-03-31
IE39602L (en) 1975-01-12
JPS5943951B2 (ja) 1984-10-25
FR2236497A1 (pl) 1975-02-07
PL94266B1 (pl) 1977-07-30
ES428185A1 (es) 1976-12-16
NL7409344A (nl) 1975-01-14
ES448397A1 (es) 1977-08-01
CH614196A5 (en) 1979-11-15
CA1025450A (en) 1978-01-31
JPS6011030B2 (ja) 1985-03-22
BE817540A (fr) 1975-01-13
SE7409146L (sv) 1975-01-13
AT337699B (de) 1977-07-11
GB1436289A (en) 1976-05-19
JPS5040578A (pl) 1975-04-14
IE39602B1 (en) 1978-11-22
AU7096974A (en) 1976-01-08
DK373974A (pl) 1975-03-03
JPS57131764A (en) 1982-08-14
ATA569674A (de) 1976-11-15
JPS57131763A (en) 1982-08-14
HU171401B (hu) 1978-01-28
CH622507A5 (en) 1981-04-15
AU477107B2 (en) 1976-10-14
DD118631A5 (pl) 1976-03-12
ES448394A1 (es) 1977-07-16
JPS5943952B2 (ja) 1984-10-25
LU70498A1 (pl) 1975-03-27

Similar Documents

Publication Publication Date Title
DE2218644C3 (de) Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2658183A1 (de) In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0002208B1 (de) Nitrosubstituierte 1,4-Dihydropyridine, diese enthaltende Arzneimittel sowie deren Herstellung
DE2335466A1 (de) Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2228363A1 (de) 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DD154014A5 (de) Verfahren zur herstellung von optisch aktiven-1,4-dihydropyridinen
DE2508181A1 (de) 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2117571A1 (de) Unsymmetrische 1,4-Dihydropyridincarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel I. Arfm: Farbenfabriken Bayer AG, 5090 Leverkusen
DE2248150A1 (de) Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2210672A1 (de) Unsymmetrische n-substituierte dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2013431B2 (de) 4-Azidophenyl-1,4-dihydropyridin-33-dicarbonsäureester
DE2210633A1 (de) Neue brueckenkopfheterocyclen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2117573A1 (de) Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridindicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
EP0009206A2 (de) Fluorhaltige 1,4-Dihydropyridine, diese enthaltende Arzneimittel sowie Verfahren zu ihrer Herstellung
DE2228377A1 (de) Dihydropyridin-carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2210667A1 (de) Kondensiert aromatisch substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2210674A1 (de) Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen sowie ihre verwendung als coronarmittel
DE2753946A1 (de) 1-n-aryl-1,4-dihydropyridine und ihre verwendung als arzneimittel
EP0039863B1 (de) 1,4-Dihydropyridine mit unterschiedlichen Substituenten in 2- und 6-Position, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
DE2658804A1 (de) Kreislaufbeeinflussende mittel
DE2242786A1 (de) Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
DE2239815C2 (de) 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2406198C2 (de) Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen
DE2738153A1 (de) 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2844595A1 (de) Acylaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Legal Events

Date Code Title Description
OD Request for examination
8130 Withdrawal