JPS57131764A - Manufacture of alkoxyalkyl-1,4-dihydropyridine ester or salts of same - Google Patents

Manufacture of alkoxyalkyl-1,4-dihydropyridine ester or salts of same

Info

Publication number
JPS57131764A
JPS57131764A JP57000455A JP45582A JPS57131764A JP S57131764 A JPS57131764 A JP S57131764A JP 57000455 A JP57000455 A JP 57000455A JP 45582 A JP45582 A JP 45582A JP S57131764 A JPS57131764 A JP S57131764A
Authority
JP
Japan
Prior art keywords
alkoxyalkyl
salts
manufacture
same
dihydropyridine ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57000455A
Other languages
Japanese (ja)
Other versions
JPS5943952B2 (en
Inventor
Botsuzaato Furiidoritsuhi
Behingaa Egubaato
Fuaataa Burufu
Suteperu Kuruto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS57131764A publication Critical patent/JPS57131764A/en
Publication of JPS5943952B2 publication Critical patent/JPS5943952B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP57000455A 1973-07-12 1982-01-06 Method for producing alkoxyalkyl-1,4-dihydropyridine ester or salt thereof Expired JPS5943952B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (en) 1973-07-12 1973-07-12 ALCOXY ALKYL-1,4-DIHYDROPYRIDINE, THE METHOD FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
DE23354667 1973-07-12

Publications (2)

Publication Number Publication Date
JPS57131764A true JPS57131764A (en) 1982-08-14
JPS5943952B2 JPS5943952B2 (en) 1984-10-25

Family

ID=5886689

Family Applications (3)

Application Number Title Priority Date Filing Date
JP49078370A Expired JPS6011030B2 (en) 1973-07-12 1974-07-10 Method for producing alkoxyalkyl 1,4-dihydropyridine ester or salt thereof
JP57000454A Expired JPS5943951B2 (en) 1973-07-12 1982-01-06 Process for producing alkoxyalkyl-1,4-dihydropyridine ester or salt thereof
JP57000455A Expired JPS5943952B2 (en) 1973-07-12 1982-01-06 Method for producing alkoxyalkyl-1,4-dihydropyridine ester or salt thereof

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP49078370A Expired JPS6011030B2 (en) 1973-07-12 1974-07-10 Method for producing alkoxyalkyl 1,4-dihydropyridine ester or salt thereof
JP57000454A Expired JPS5943951B2 (en) 1973-07-12 1982-01-06 Process for producing alkoxyalkyl-1,4-dihydropyridine ester or salt thereof

Country Status (21)

Country Link
JP (3) JPS6011030B2 (en)
AT (1) AT337699B (en)
AU (1) AU477107B2 (en)
BE (1) BE817540A (en)
CA (1) CA1025450A (en)
CH (2) CH614196A5 (en)
DD (1) DD118631A5 (en)
DE (1) DE2335466A1 (en)
DK (1) DK373974A (en)
ES (5) ES428185A1 (en)
FI (1) FI212074A (en)
FR (1) FR2236497B1 (en)
GB (1) GB1436289A (en)
HU (1) HU171401B (en)
IE (1) IE39602B1 (en)
IL (1) IL45233A (en)
LU (1) LU70498A1 (en)
NL (1) NL7409344A (en)
PL (2) PL94266B1 (en)
SE (1) SE7409146L (en)
ZA (1) ZA744461B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
JPS53146941U (en) * 1977-04-26 1978-11-18
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
DE3312283A1 (en) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING UNBALANCED 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3312216A1 (en) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING SYMMETRIC 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3432563A1 (en) * 1984-09-05 1986-03-13 Bayer Ag, 5090 Leverkusen NEW PYRIDYLETHYL DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
FI862343A (en) 1985-06-17 1986-12-18 Warner Lambert Co FRAME FOR THE PREPARATION OF THERAPEUTIC NETWORK 1,4-DIHYDROPYRIDIN INFOERING.
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (en) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル Number detector for vehicle
AT399872B (en) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Prodn. of 1,4-di:hydro-pyridine deriv. - by reacting new 2-nitro-benzylidne-amine cpds. with methyl actoacetate, used for treating hypertension
AT400241B (en) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of a 1,4-dihydropyridine derivative
AT399873B (en) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of a 1,4-dihydropyridine derivative
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
FR2672890A1 (en) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol 2,6-DIMETHYL-4- (4'-HYDROXY-3 ', 5'-DI-T-BUTYLPHENYL) -1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SENSORS OF FREE RADICALS.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (en) * 1969-05-10 1978-11-23 Bayer Ag Process for the preparation of N-substituted M-dihydropyridine-S.S-dicarboxylic acid esters

Also Published As

Publication number Publication date
ES448396A1 (en) 1977-09-16
PL94266B1 (en) 1977-07-30
JPS57131763A (en) 1982-08-14
ATA569674A (en) 1976-11-15
DK373974A (en) 1975-03-03
PL91873B1 (en) 1977-03-31
FR2236497B1 (en) 1978-07-21
NL7409344A (en) 1975-01-14
HU171401B (en) 1978-01-28
FR2236497A1 (en) 1975-02-07
CH614196A5 (en) 1979-11-15
BE817540A (en) 1975-01-13
LU70498A1 (en) 1975-03-27
CA1025450A (en) 1978-01-31
JPS6011030B2 (en) 1985-03-22
GB1436289A (en) 1976-05-19
ES448397A1 (en) 1977-08-01
DE2335466A1 (en) 1975-01-30
ES428185A1 (en) 1976-12-16
JPS5943951B2 (en) 1984-10-25
JPS5943952B2 (en) 1984-10-25
IE39602B1 (en) 1978-11-22
AU477107B2 (en) 1976-10-14
DD118631A5 (en) 1976-03-12
IL45233A (en) 1978-06-15
CH622507A5 (en) 1981-04-15
SE7409146L (en) 1975-01-13
FI212074A (en) 1975-01-13
ZA744461B (en) 1975-07-30
AU7096974A (en) 1976-01-08
JPS5040578A (en) 1975-04-14
ES448395A1 (en) 1977-09-16
ES448394A1 (en) 1977-07-16
IL45233A0 (en) 1974-10-22
IE39602L (en) 1975-01-12
AT337699B (en) 1977-07-11

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