GB1539897A - Phenoxypropionic acid derivatives - Google Patents

Phenoxypropionic acid derivatives

Info

Publication number
GB1539897A
GB1539897A GB5979/75A GB597975A GB1539897A GB 1539897 A GB1539897 A GB 1539897A GB 5979/75 A GB5979/75 A GB 5979/75A GB 597975 A GB597975 A GB 597975A GB 1539897 A GB1539897 A GB 1539897A
Authority
GB
United Kingdom
Prior art keywords
acid derivatives
phenoxypropionic acid
phenoxypropionic
derivatives
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5979/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchimed SA
Original Assignee
Orchimed SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchimed SA filed Critical Orchimed SA
Priority to GB5979/75A priority Critical patent/GB1539897A/en
Priority to JP51003961A priority patent/JPS5195049A/en
Priority to CH128376A priority patent/CH617657A5/fr
Priority to DK49676*#A priority patent/DK49676A/en
Priority to US05/656,711 priority patent/US4072705A/en
Priority to SE7601370A priority patent/SE430329B/en
Priority to AR262192A priority patent/AR222773A1/en
Priority to IE256/76A priority patent/IE43078B1/en
Priority to ES445075A priority patent/ES445075A1/en
Priority to CA245,489A priority patent/CA1069523A/en
Priority to DE2605382A priority patent/DE2605382C2/en
Priority to BE2054818A priority patent/BE838435A/en
Priority to FI760328A priority patent/FI760328A/fi
Priority to NO760440A priority patent/NO760440L/no
Priority to LU74331A priority patent/LU74331A1/xx
Priority to NL7601461A priority patent/NL7601461A/en
Priority to MX276D priority patent/MX3485E/en
Priority to AU11053/76A priority patent/AU512971B2/en
Priority to FR7603876A priority patent/FR2300552A1/en
Priority to DD191218A priority patent/DD124115A5/xx
Priority to JP51014389A priority patent/JPS51131843A/en
Priority to DD76196964A priority patent/DD143909A5/en
Priority to ZA760826A priority patent/ZA76826B/en
Priority to FR7637022A priority patent/FR2342723A1/en
Priority to AR266873A priority patent/AR223305A1/en
Priority to NO771367A priority patent/NO771367L/no
Priority to US05/846,323 priority patent/US4179515A/en
Priority to US05/846,324 priority patent/US4235896A/en
Priority to CH834978A priority patent/CH620415A5/fr
Priority to CA310,733A priority patent/CA1072110A/en
Publication of GB1539897A publication Critical patent/GB1539897A/en
Priority to SE8005647A priority patent/SE447651B/en
Priority to FI820277A priority patent/FI820277L/en
Priority to FI850154A priority patent/FI71301C/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
GB5979/75A 1975-02-02 1975-02-12 Phenoxypropionic acid derivatives Expired GB1539897A (en)

Priority Applications (33)

Application Number Priority Date Filing Date Title
GB5979/75A GB1539897A (en) 1975-02-12 1975-02-12 Phenoxypropionic acid derivatives
JP51003961A JPS5195049A (en) 1975-02-12 1976-01-16 * **********so*****no***tsu*****************************************ni*no
CH128376A CH617657A5 (en) 1975-02-12 1976-02-02
DK49676*#A DK49676A (en) 1975-02-12 1976-02-06 PROCEDURE FOR THE MANUFACTURE OF HYPOLIPIDE MEANS
US05/656,711 US4072705A (en) 1975-02-12 1976-02-09 Phenylmethylphenoxy propionic acid esters
SE7601370A SE430329B (en) 1975-02-12 1976-02-09 PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY EFFECTIVE ASSOCIATIONS
AR262192A AR222773A1 (en) 1975-02-12 1976-02-09 PROCEDURE FOR THE PREPARATION OF ACID DERIVATIVES 2- (4-CARBONYLPHENOXY)) - 2-METHYLPROPIONIC
IE256/76A IE43078B1 (en) 1975-02-12 1976-02-09 Phenoxypropionic acid derivatives
ES445075A ES445075A1 (en) 1975-02-12 1976-02-11 Phenylmethylphenoxy propionic acid esters
CA245,489A CA1069523A (en) 1975-02-12 1976-02-11 Process for preparing hypolipidaemiant products
DE2605382A DE2605382C2 (en) 1975-02-12 1976-02-11 Process for the preparation of 2-p-benzoylphenoxy-2-methylpropionic acid compounds
BE2054818A BE838435A (en) 1975-02-12 1976-02-11 HYPOLIPIDEMATING COMPOUNDS
FI760328A FI760328A (en) 1975-02-12 1976-02-11
NO760440A NO760440L (en) 1975-02-12 1976-02-11
LU74331A LU74331A1 (en) 1975-02-12 1976-02-11
AU11053/76A AU512971B2 (en) 1975-02-02 1976-02-12 Phenoxypropionic acid derivatives
MX276D MX3485E (en) 1975-02-12 1976-02-12 PROCEDURE FOR THE PREPARATION OF ACIDS p- (ALKYL-CARBONYL) -PHENOXY-ALKYL-CARBOXYLICS
NL7601461A NL7601461A (en) 1975-02-12 1976-02-12 PREPARATION AGAINST HYPOLIPIDEMIA.
FR7603876A FR2300552A1 (en) 1975-02-12 1976-02-12 HYPOLIPIDEMATING COMPOUNDS
DD191218A DD124115A5 (en) 1975-02-12 1976-02-12
JP51014389A JPS51131843A (en) 1975-02-12 1976-02-12 Lipidddepleted active compound
DD76196964A DD143909A5 (en) 1975-02-12 1976-02-12 PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED PHENOXY DERIVATIVES
ZA760826A ZA76826B (en) 1975-02-12 1976-02-12 Improvements in or relating to industrial products which are particularly useful in therapeutics as active medicaments in the cardiovascular field and processes therefor
FR7637022A FR2342723A1 (en) 1975-02-12 1976-12-08 HYPOLIPIDEMATING COMPOUNDS
AR266873A AR223305A1 (en) 1975-02-12 1977-03-16 PROCEDURE FOR THE PREPARATION OF ALPHA ACID DERIVATIVES- (PHENYL-4'-SUBSTITUTED) -P-METHYLPHENOXY ALKYL CARBOXYLICS
NO771367A NO771367L (en) 1975-02-12 1977-04-20
US05/846,323 US4179515A (en) 1975-02-12 1977-10-28 Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition
US05/846,324 US4235896A (en) 1975-02-12 1977-10-28 Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same
CH834978A CH620415A5 (en) 1975-02-12 1978-08-04
CA310,733A CA1072110A (en) 1975-02-12 1978-09-06 Process for preparing hypolipidaemiant products
SE8005647A SE447651B (en) 1975-02-12 1980-08-11 SET TO PREPARE 2- / 4- (P-CHLOROBENOYL) PHENOXY / -2-METHYL-PROPIONIC ACID AND ITS ISOPROPYLESTER
FI820277A FI820277L (en) 1975-02-12 1982-01-28 FRAMEWORK FOR LAMINATION OF LIPIDEMINEDSAETTANDE FOERENINGAR
FI850154A FI71301C (en) 1975-02-12 1985-01-14 NOW FOERFARANDE FOER FRAMSTAELLNING AV P-BENSOYLFENOXIALKANSYRADERIVAT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5979/75A GB1539897A (en) 1975-02-12 1975-02-12 Phenoxypropionic acid derivatives

Publications (1)

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GB1539897A true GB1539897A (en) 1979-02-07

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ZA (1) ZA76826B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014440A1 (en) * 1979-02-02 1980-08-20 Sagami Chemical Research Center Ketal derivatives and the use thereof as intermediate products
EP0036218A2 (en) * 1980-03-19 1981-09-23 D and D S.r.l. Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions
FR2534582A1 (en) * 1982-10-19 1984-04-20 Kotobuki Seiyaku Co Ltd NOVEL BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES, USEFUL AS ANTI-HYPERURICEMIA AND ANTI-HYPERTENSION AGENTS, AND PROCESS FOR THEIR MANUFACTURE
EP0287882A1 (en) * 1987-04-08 1988-10-26 Hoechst Aktiengesellschaft Synthesis of peptidamides by the solid phase method using anchor groups unstable as to acids
CN106478447A (en) * 2015-09-01 2017-03-08 上海医药工业研究院 Carboxylic acid derivates and its application as FXR antagonist

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014440A1 (en) * 1979-02-02 1980-08-20 Sagami Chemical Research Center Ketal derivatives and the use thereof as intermediate products
EP0036218A2 (en) * 1980-03-19 1981-09-23 D and D S.r.l. Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions
EP0036218A3 (en) * 1980-03-19 1981-12-30 D And D S.R.L. Quinuclidinic esters and derivatives of phenoxycarboxylic acids, a process for the preparation thereof, and related pharmaceutical compositions
FR2534582A1 (en) * 1982-10-19 1984-04-20 Kotobuki Seiyaku Co Ltd NOVEL BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES, USEFUL AS ANTI-HYPERURICEMIA AND ANTI-HYPERTENSION AGENTS, AND PROCESS FOR THEIR MANUFACTURE
US4797415A (en) * 1982-10-19 1989-01-10 Kotobuki Seiyaku Company Limited Benzofuran derivatives and use thereof for treating hyperuricemia
EP0287882A1 (en) * 1987-04-08 1988-10-26 Hoechst Aktiengesellschaft Synthesis of peptidamides by the solid phase method using anchor groups unstable as to acids
CN106478447A (en) * 2015-09-01 2017-03-08 上海医药工业研究院 Carboxylic acid derivates and its application as FXR antagonist
CN106478447B (en) * 2015-09-01 2018-10-30 上海医药工业研究院 Carboxylic acid derivates and its application as FXR antagonists

Also Published As

Publication number Publication date
BE838435A (en) 1976-08-11
ZA76826B (en) 1977-09-28

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