ZA744461B - New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use - Google Patents

New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use

Info

Publication number
ZA744461B
ZA744461B ZA00744461A ZA744461A ZA744461B ZA 744461 B ZA744461 B ZA 744461B ZA 00744461 A ZA00744461 A ZA 00744461A ZA 744461 A ZA744461 A ZA 744461A ZA 744461 B ZA744461 B ZA 744461B
Authority
ZA
South Africa
Prior art keywords
dihydropyridines
alkoxyalkyl
preparation
new
medicinal use
Prior art date
Application number
ZA00744461A
Other languages
English (en)
Inventor
K Stoepel
E Wehinger
W Vater
F Bossert
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA744461B publication Critical patent/ZA744461B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA00744461A 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use ZA744461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA744461B true ZA744461B (en) 1975-07-30

Family

ID=5886689

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00744461A ZA744461B (en) 1973-07-12 1974-07-11 New alkoxyalkyl-1,4-dihydropyridines, their preparation and their medicinal use

Country Status (21)

Country Link
JP (3) JPS6011030B2 (pl)
AT (1) AT337699B (pl)
AU (1) AU477107B2 (pl)
BE (1) BE817540A (pl)
CA (1) CA1025450A (pl)
CH (2) CH614196A5 (pl)
DD (1) DD118631A5 (pl)
DE (1) DE2335466A1 (pl)
DK (1) DK373974A (pl)
ES (5) ES428185A1 (pl)
FI (1) FI212074A (pl)
FR (1) FR2236497B1 (pl)
GB (1) GB1436289A (pl)
HU (1) HU171401B (pl)
IE (1) IE39602B1 (pl)
IL (1) IL45233A (pl)
LU (1) LU70498A1 (pl)
NL (1) NL7409344A (pl)
PL (2) PL94266B1 (pl)
SE (1) SE7409146L (pl)
ZA (1) ZA744461B (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
JPS53146941U (pl) * 1977-04-26 1978-11-18
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3432563A1 (de) * 1984-09-05 1986-03-13 Bayer Ag, 5090 Leverkusen Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
CA1267416A (en) 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (ja) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル 車両の台数検出装置
AT399872B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
AT400241B (de) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT399873B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Also Published As

Publication number Publication date
FR2236497B1 (pl) 1978-07-21
ES448396A1 (es) 1977-09-16
IL45233A (en) 1978-06-15
IL45233A0 (en) 1974-10-22
ES448395A1 (es) 1977-09-16
FI212074A (pl) 1975-01-13
PL91873B1 (pl) 1977-03-31
IE39602L (en) 1975-01-12
JPS5943951B2 (ja) 1984-10-25
FR2236497A1 (pl) 1975-02-07
PL94266B1 (pl) 1977-07-30
ES428185A1 (es) 1976-12-16
NL7409344A (nl) 1975-01-14
ES448397A1 (es) 1977-08-01
CH614196A5 (en) 1979-11-15
CA1025450A (en) 1978-01-31
DE2335466A1 (de) 1975-01-30
JPS6011030B2 (ja) 1985-03-22
BE817540A (fr) 1975-01-13
SE7409146L (sv) 1975-01-13
AT337699B (de) 1977-07-11
GB1436289A (en) 1976-05-19
JPS5040578A (pl) 1975-04-14
IE39602B1 (en) 1978-11-22
AU7096974A (en) 1976-01-08
DK373974A (pl) 1975-03-03
JPS57131764A (en) 1982-08-14
ATA569674A (de) 1976-11-15
JPS57131763A (en) 1982-08-14
HU171401B (hu) 1978-01-28
CH622507A5 (en) 1981-04-15
AU477107B2 (en) 1976-10-14
DD118631A5 (pl) 1976-03-12
ES448394A1 (es) 1977-07-16
JPS5943952B2 (ja) 1984-10-25
LU70498A1 (pl) 1975-03-27

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