DE2307010C2 - Verfahren zur Herstellung von LH- und FSH-Releasing Hormon, hierbei eingesetzte Zwischenprodukte und Verfahren zu deren Herstellung - Google Patents

Verfahren zur Herstellung von LH- und FSH-Releasing Hormon, hierbei eingesetzte Zwischenprodukte und Verfahren zu deren Herstellung

Info

Publication number
DE2307010C2
DE2307010C2 DE2307010A DE2307010A DE2307010C2 DE 2307010 C2 DE2307010 C2 DE 2307010C2 DE 2307010 A DE2307010 A DE 2307010A DE 2307010 A DE2307010 A DE 2307010A DE 2307010 C2 DE2307010 C2 DE 2307010C2
Authority
DE
Germany
Prior art keywords
solution
ester
acid
mixture
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2307010A
Other languages
German (de)
English (en)
Other versions
DE2307010A1 (de
Inventor
Manfred Karl Hudson Götz
Hans Ueli St. Laurent Montreal Immer
Verner Robert Kirkland Quebec Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00226508A external-priority patent/US3835108A/en
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Publication of DE2307010A1 publication Critical patent/DE2307010A1/de
Application granted granted Critical
Publication of DE2307010C2 publication Critical patent/DE2307010C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE2307010A 1972-02-15 1973-02-13 Verfahren zur Herstellung von LH- und FSH-Releasing Hormon, hierbei eingesetzte Zwischenprodukte und Verfahren zu deren Herstellung Expired DE2307010C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00226508A US3835108A (en) 1972-02-15 1972-02-15 Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US24346572A 1972-04-12 1972-04-12

Publications (2)

Publication Number Publication Date
DE2307010A1 DE2307010A1 (de) 1973-08-23
DE2307010C2 true DE2307010C2 (de) 1986-08-21

Family

ID=26920599

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2307010A Expired DE2307010C2 (de) 1972-02-15 1973-02-13 Verfahren zur Herstellung von LH- und FSH-Releasing Hormon, hierbei eingesetzte Zwischenprodukte und Verfahren zu deren Herstellung

Country Status (9)

Country Link
JP (1) JPS5729462B2 (hu)
CA (1) CA1025441A (hu)
CH (1) CH589608A5 (hu)
DE (1) DE2307010C2 (hu)
FR (1) FR2181730B1 (hu)
GB (3) GB1425512A (hu)
IL (3) IL48514A (hu)
NZ (1) NZ169577A (hu)
SE (1) SE403772B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454879B (sv) * 1982-06-29 1988-06-06 Astra Laekemedel Ab Alfa-bromodietylkarbonat samt dess anvendning som mellanprodukt vid framstellning av penicillin g

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS528831B2 (hu) * 1971-10-04 1977-03-11

Also Published As

Publication number Publication date
IL41313A0 (en) 1973-03-30
GB1425511A (en) 1976-02-18
DE2307010A1 (de) 1973-08-23
GB1425513A (en) 1976-02-18
GB1425512A (en) 1976-02-18
IL48514A0 (en) 1976-01-30
CH589608A5 (hu) 1977-07-15
SE403772B (sv) 1978-09-04
JPS4886868A (hu) 1973-11-15
FR2181730B1 (hu) 1977-07-15
IL48514A (en) 1976-08-31
CA1025441A (en) 1978-01-31
IL41313A (en) 1976-08-31
FR2181730A1 (hu) 1973-12-07
NZ169577A (en) 1984-09-28
JPS5729462B2 (hu) 1982-06-23

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Legal Events

Date Code Title Description
OD Request for examination
D2 Grant after examination
8364 No opposition during term of opposition