GB1425513A - N-n-n-n-l-leucyl-l-arginyl-l-prolyl-glycinamide diacetate - Google Patents

N-n-n-n-l-leucyl-l-arginyl-l-prolyl-glycinamide diacetate

Info

Publication number
GB1425513A
GB1425513A GB3217475A GB3217475A GB1425513A GB 1425513 A GB1425513 A GB 1425513A GB 3217475 A GB3217475 A GB 3217475A GB 3217475 A GB3217475 A GB 3217475A GB 1425513 A GB1425513 A GB 1425513A
Authority
GB
United Kingdom
Prior art keywords
glycinamide
arginyl
leucyl
prolyl
diacetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3217475A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00226508A external-priority patent/US3835108A/en
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Publication of GB1425513A publication Critical patent/GB1425513A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1425513 Tetrapeptide AYERST MCKENNA & HARRISON Ltd 14 Feb 1973 [15 Feb 1972 12 April 1972) 32174/75 Divided out of 1425511 Heading C3H The novel tetrapeptide H-Leu-Arg-Pro-Gly- NH 2 .2CH 3 COOH is prepared by conventional methods of peptide chemistry.
GB3217475A 1972-02-15 1973-02-14 N-n-n-n-l-leucyl-l-arginyl-l-prolyl-glycinamide diacetate Expired GB1425513A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00226508A US3835108A (en) 1972-02-15 1972-02-15 Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US24346572A 1972-04-12 1972-04-12

Publications (1)

Publication Number Publication Date
GB1425513A true GB1425513A (en) 1976-02-18

Family

ID=26920599

Family Applications (3)

Application Number Title Priority Date Filing Date
GB3217475A Expired GB1425513A (en) 1972-02-15 1973-02-14 N-n-n-n-l-leucyl-l-arginyl-l-prolyl-glycinamide diacetate
GB718073A Expired GB1425511A (en) 1972-02-15 1973-02-14 Lh-and fsh-releasing hormones
GB3217675A Expired GB1425512A (en) 1972-02-15 1973-02-14 N-n-n-n-n-5-oxo-l-prolyl-l-histidyl-l-triptophyl-l-seryl-l- tyrosyl- glycerine hydrazide trifluoroacetate

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB718073A Expired GB1425511A (en) 1972-02-15 1973-02-14 Lh-and fsh-releasing hormones
GB3217675A Expired GB1425512A (en) 1972-02-15 1973-02-14 N-n-n-n-n-5-oxo-l-prolyl-l-histidyl-l-triptophyl-l-seryl-l- tyrosyl- glycerine hydrazide trifluoroacetate

Country Status (9)

Country Link
JP (1) JPS5729462B2 (en)
CA (1) CA1025441A (en)
CH (1) CH589608A5 (en)
DE (1) DE2307010C2 (en)
FR (1) FR2181730B1 (en)
GB (3) GB1425513A (en)
IL (3) IL41313A (en)
NZ (1) NZ169577A (en)
SE (1) SE403772B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68992A (en) * 1982-06-29 1991-06-10 Astra Laekemedel Ab Alpha-bromo diethyl carbonate and process for the preparation of ethoxycarbonyloxy esters of penicillanic acids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS528831B2 (en) * 1971-10-04 1977-03-11

Also Published As

Publication number Publication date
JPS5729462B2 (en) 1982-06-23
GB1425511A (en) 1976-02-18
CH589608A5 (en) 1977-07-15
CA1025441A (en) 1978-01-31
SE403772B (en) 1978-09-04
IL48514A (en) 1976-08-31
IL41313A0 (en) 1973-03-30
DE2307010C2 (en) 1986-08-21
JPS4886868A (en) 1973-11-15
DE2307010A1 (en) 1973-08-23
GB1425512A (en) 1976-02-18
NZ169577A (en) 1984-09-28
IL48514A0 (en) 1976-01-30
FR2181730A1 (en) 1973-12-07
IL41313A (en) 1976-08-31
FR2181730B1 (en) 1977-07-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19930212