DE2128605A1 - Neue Cephalosporansäurederivaten und Verfahren zu ihrer Herstellung - Google Patents

Neue Cephalosporansäurederivaten und Verfahren zu ihrer Herstellung

Info

Publication number
DE2128605A1
DE2128605A1 DE19712128605 DE2128605A DE2128605A1 DE 2128605 A1 DE2128605 A1 DE 2128605A1 DE 19712128605 DE19712128605 DE 19712128605 DE 2128605 A DE2128605 A DE 2128605A DE 2128605 A1 DE2128605 A1 DE 2128605A1
Authority
DE
Germany
Prior art keywords
compounds
formula
ester group
substituted
substituted methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712128605
Other languages
German (de)
English (en)
Inventor
Hans Dr. Binningen; Peter Heinrich Dr. Riehen; Bickel (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2128605A1 publication Critical patent/DE2128605A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE19712128605 1970-06-18 1971-06-09 Neue Cephalosporansäurederivaten und Verfahren zu ihrer Herstellung Pending DE2128605A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH923270 1970-06-18

Publications (1)

Publication Number Publication Date
DE2128605A1 true DE2128605A1 (de) 1971-12-23

Family

ID=4349775

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712128605 Pending DE2128605A1 (de) 1970-06-18 1971-06-09 Neue Cephalosporansäurederivaten und Verfahren zu ihrer Herstellung

Country Status (12)

Country Link
AT (1) AT304762B (enrdf_load_stackoverflow)
BE (1) BE768653A (enrdf_load_stackoverflow)
CA (1) CA929517A (enrdf_load_stackoverflow)
CH (1) CH546794A (enrdf_load_stackoverflow)
DE (1) DE2128605A1 (enrdf_load_stackoverflow)
FR (1) FR2100776B1 (enrdf_load_stackoverflow)
GB (1) GB1356437A (enrdf_load_stackoverflow)
HU (1) HU163508B (enrdf_load_stackoverflow)
IE (1) IE35366B1 (enrdf_load_stackoverflow)
NL (1) NL7108351A (enrdf_load_stackoverflow)
SE (1) SE379354B (enrdf_load_stackoverflow)
SU (1) SU414793A3 (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2360620A1 (de) * 1972-12-08 1974-06-12 Takeda Chemical Industries Ltd Verfahren zur herstellung von lactolartigen cephalosporinen
JPS55136290A (en) * 1972-06-29 1980-10-23 Ciba Geigy Ag Manufacture of 7betaaaminoocephamm33onee44 carboxylic acid compound
US5631366A (en) * 1995-01-12 1997-05-20 Hoffmann-La Roche Inc. Process for making 3-formylcephem derivatives
AT402929B (de) * 1994-05-25 1997-09-25 Biochemie Gmbh Neue cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE412238B (sv) * 1971-05-24 1980-02-25 Ciba Geigy Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening
US4122260A (en) * 1977-10-04 1978-10-24 Yeda Research And Development Co., Ltd. Cephalosporin derivatives
ATE335747T1 (de) 1999-09-30 2006-09-15 Otsuka Kagaku Kk Kristallines 3-cephem derivat

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH549053A (de) * 1967-11-03 1974-05-15 Ciba Geigy Ag Verfahren zur herstellung von 7-substituierten 3-desacetylisocephalosporansaeuren.

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55136290A (en) * 1972-06-29 1980-10-23 Ciba Geigy Ag Manufacture of 7betaaaminoocephamm33onee44 carboxylic acid compound
DE2360620A1 (de) * 1972-12-08 1974-06-12 Takeda Chemical Industries Ltd Verfahren zur herstellung von lactolartigen cephalosporinen
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
US6034237A (en) * 1994-04-25 2000-03-07 Biochemie Gesellschaft M.B.H. 3-imino-cephalosporins
US6063917A (en) * 1994-04-25 2000-05-16 Biochemie Gesellschaft M.B.H. Cephalosporin synthesis
US6093813A (en) * 1994-04-25 2000-07-25 Biochemie Gesellschaft M.B.H. Cephalosporin compounds
AT402929B (de) * 1994-05-25 1997-09-25 Biochemie Gmbh Neue cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
US5631366A (en) * 1995-01-12 1997-05-20 Hoffmann-La Roche Inc. Process for making 3-formylcephem derivatives

Also Published As

Publication number Publication date
NL7108351A (enrdf_load_stackoverflow) 1971-12-21
CH546794A (de) 1974-03-15
AT304762B (de) 1973-01-25
BE768653A (fr) 1971-12-17
GB1356437A (en) 1974-06-12
FR2100776A1 (enrdf_load_stackoverflow) 1972-03-24
SE379354B (enrdf_load_stackoverflow) 1975-10-06
IE35366B1 (en) 1976-01-21
FR2100776B1 (enrdf_load_stackoverflow) 1974-08-30
HU163508B (enrdf_load_stackoverflow) 1973-09-27
IE35366L (en) 1971-12-18
SU414793A3 (enrdf_load_stackoverflow) 1974-02-05
CA929517A (en) 1973-07-03

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