DE2119966A1 - Verbessertes Verfahren zur Herstellung von L-Pyroglutamyl-L-histidyl-L-prolinamid - Google Patents

Verbessertes Verfahren zur Herstellung von L-Pyroglutamyl-L-histidyl-L-prolinamid

Info

Publication number
DE2119966A1
DE2119966A1 DE19712119966 DE2119966A DE2119966A1 DE 2119966 A1 DE2119966 A1 DE 2119966A1 DE 19712119966 DE19712119966 DE 19712119966 DE 2119966 A DE2119966 A DE 2119966A DE 2119966 A1 DE2119966 A1 DE 2119966A1
Authority
DE
Germany
Prior art keywords
group
tosyl
solution
prolinamide
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712119966
Other languages
German (de)
English (en)
Inventor
Shumpei Suita; Fujii Toshiyuki Minoo; Osaka Sakakibara (Japan). P
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE2119966A1 publication Critical patent/DE2119966A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
DE19712119966 1970-04-25 1971-04-23 Verbessertes Verfahren zur Herstellung von L-Pyroglutamyl-L-histidyl-L-prolinamid Pending DE2119966A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP45035524A JPS4829225B1 (cg-RX-API-DMAC7.html) 1970-04-25 1970-04-25

Publications (1)

Publication Number Publication Date
DE2119966A1 true DE2119966A1 (de) 1971-11-25

Family

ID=12444122

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712119966 Pending DE2119966A1 (de) 1970-04-25 1971-04-23 Verbessertes Verfahren zur Herstellung von L-Pyroglutamyl-L-histidyl-L-prolinamid

Country Status (4)

Country Link
JP (1) JPS4829225B1 (cg-RX-API-DMAC7.html)
CH (1) CH557362A (cg-RX-API-DMAC7.html)
DE (1) DE2119966A1 (cg-RX-API-DMAC7.html)
FR (1) FR2090682A5 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793987A (fr) * 1972-01-20 1973-05-02 Reckitt & Colmann Prod Ltd Derive de l'histidine
JPS5225939A (en) * 1975-08-25 1977-02-26 Hitachi Ltd Ignition timing controller
JPS5234143A (en) * 1975-09-12 1977-03-15 Hitachi Ltd Depression-type ignition time adjusting device of distributor for inte rnal combustion engine
EP0749978A4 (en) * 1994-01-31 1997-10-01 Japan Tobacco Inc METHOD FOR SEPARATING AND PURIFYING TRH ANALOGS, AND METHOD FOR PRODUCING SOLVATES OF TRH ANALOGS

Also Published As

Publication number Publication date
FR2090682A5 (en) 1972-01-14
CH557362A (de) 1974-12-31
JPS4829225B1 (cg-RX-API-DMAC7.html) 1973-09-08

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