DE2114461A1 - Neue Fluoren bzw Fluorenondenvate und Verfahren zur Herstellung derselben - Google Patents

Neue Fluoren bzw Fluorenondenvate und Verfahren zur Herstellung derselben

Info

Publication number
DE2114461A1
DE2114461A1 DE19712114461 DE2114461A DE2114461A1 DE 2114461 A1 DE2114461 A1 DE 2114461A1 DE 19712114461 DE19712114461 DE 19712114461 DE 2114461 A DE2114461 A DE 2114461A DE 2114461 A1 DE2114461 A1 DE 2114461A1
Authority
DE
Germany
Prior art keywords
fluorene
bis
general formula
group
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19712114461
Other languages
German (de)
English (en)
Inventor
Robert Willerton Wyoming Sill Arthur DeWitt Greenhills Albrecht William Lind Horgan Stephen William Cincinnati Ohio Fleming (V St A )
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DE2114461A1 publication Critical patent/DE2114461A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19712114461 1970-03-27 1971-03-25 Neue Fluoren bzw Fluorenondenvate und Verfahren zur Herstellung derselben Withdrawn DE2114461A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2346870A 1970-03-27 1970-03-27

Publications (1)

Publication Number Publication Date
DE2114461A1 true DE2114461A1 (de) 1971-10-14

Family

ID=21815282

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712114461 Withdrawn DE2114461A1 (de) 1970-03-27 1971-03-25 Neue Fluoren bzw Fluorenondenvate und Verfahren zur Herstellung derselben

Country Status (19)

Country Link
US (1) US4064347A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5429488B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT304515B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE764870A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA959488A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH564518A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS179369B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2114461A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES389604A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2085747B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1286775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU162836B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE35023B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL36423A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7104096A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO130513C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH9308A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE374540B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA711333B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105772A1 (de) 2004-04-14 2005-11-10 Merck Patent Gmbh Dibenzofuran-, dibenzothiophen- und fluorenderivate

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3859286A (en) * 1970-12-11 1975-01-07 Richardson Merrell Inc Bis-basic ketones of xanthene and xanthen-9-one
US4048230A (en) * 1972-12-21 1977-09-13 Richardson-Merrell Inc. Aminoacetyl-acenaphthenes
US4108896A (en) * 1972-12-21 1978-08-22 Richardson-Merrell Inc. Anthracene derivatives
US3983124A (en) 1972-12-21 1976-09-28 Richardson-Merrell Inc. Fluorene compounds
US4461899A (en) * 1982-05-24 1984-07-24 Diamond Shamrock Chemicals Company Fluorenecarboxylic acid derivatives
US6004959A (en) * 1996-05-30 1999-12-21 Hoechst Marion Roussel, Inc. Alkyloxyamino substituted fluorenones and their use as protein kinase-C inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB286688A (en) 1927-03-09 1929-05-16 Schering Kahlbaum Ag Process for the manufacture of new di-halogen-acylated diphenylethers and of highly active therapeutic substances therefrom
US2840558A (en) * 1954-06-30 1958-06-24 Shell Dev Mannich bases of aromatic polyketones
US2783216A (en) * 1954-06-30 1957-02-26 Shell Dev Resinous products from mannich bases of aromatic polyketones with hydrogen sulfide andor polythiols
NL132583C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1960-11-09 1971-10-15
US3083201A (en) * 1961-02-13 1963-03-26 Smith Kline French Lab Glyoxal derivatives of dibenzofuran and dibenzothiophene
US3251733A (en) * 1961-06-07 1966-05-17 Geigy Chem Corp Antimicrobic compositions and process for protection of organic materials therewith
US3576865A (en) * 1968-10-11 1971-04-27 Richardson Merrell Inc Fluorenone-,fluorenol-,and fluorenebis-basic carboxamides

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105772A1 (de) 2004-04-14 2005-11-10 Merck Patent Gmbh Dibenzofuran-, dibenzothiophen- und fluorenderivate
US7514127B2 (en) 2004-04-14 2009-04-07 Merck Patent Gmbh Dibenzofuran derivatives, dibenzothiophene derivatives and fluorene derivatives

Also Published As

Publication number Publication date
US4064347A (en) 1977-12-20
JPS5429488B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-09-25
SE374540B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-03-10
FR2085747A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-12-31
HU162836B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-04-28
ZA711333B (en) 1971-11-24
PH9308A (en) 1975-08-18
IE35023B1 (en) 1975-10-15
IL36423A (en) 1974-05-16
CH569694A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-11-28
BE764870A (fr) 1971-08-16
NO130513B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-09-16
IE35023L (en) 1971-09-27
ES389604A1 (es) 1973-06-16
NL7104096A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-09-29
FR2085747B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-08-01
CS179369B2 (en) 1977-10-31
CA959488A (en) 1974-12-17
GB1286775A (en) 1972-08-23
NO130513C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-12-27
IL36423A0 (en) 1971-05-26
CH564518A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-31
AT304515B (de) 1973-01-10

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Legal Events

Date Code Title Description
OD Request for examination
8126 Change of the secondary classification

Free format text: C07C121/46 C07D211/14 C07D295/10 A61K 31/135 A61K 31/445 A61K 31/535

8136 Disposal/non-payment of the fee for publication/grant