DE2101345A1 - Verfahren zur Herstellung von Cephalosporin C - Google Patents

Verfahren zur Herstellung von Cephalosporin C

Info

Publication number
DE2101345A1
DE2101345A1 DE19712101345 DE2101345A DE2101345A1 DE 2101345 A1 DE2101345 A1 DE 2101345A1 DE 19712101345 DE19712101345 DE 19712101345 DE 2101345 A DE2101345 A DE 2101345A DE 2101345 A1 DE2101345 A1 DE 2101345A1
Authority
DE
Germany
Prior art keywords
methionine
mutants
cephalosporin
medium
sulfur compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712101345
Other languages
German (de)
English (en)
Inventor
Hans Jörg Dr Buus Nuesch Jakob Dr Riehen Treichler, (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2101345A1 publication Critical patent/DE2101345A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06Cephalosporin C; Derivatives thereof
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/925Cephalosporium

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19712101345 1970-01-21 1971-01-13 Verfahren zur Herstellung von Cephalosporin C Pending DE2101345A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH81170A CH553850A (de) 1970-01-21 1970-01-21 Verfahren zur darstellung von fuer die gesteuerte biosynthese von cephalosporin c, geeigneten mangel-mutanten und deren verwendung zur gesteuerten biosynthese von cephalosporin c.

Publications (1)

Publication Number Publication Date
DE2101345A1 true DE2101345A1 (de) 1971-07-29

Family

ID=4195720

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712101345 Pending DE2101345A1 (de) 1970-01-21 1971-01-13 Verfahren zur Herstellung von Cephalosporin C

Country Status (6)

Country Link
US (1) US3776815A (OSRAM)
CH (1) CH553850A (OSRAM)
DE (1) DE2101345A1 (OSRAM)
FR (1) FR2081445B1 (OSRAM)
GB (1) GB1335264A (OSRAM)
NL (1) NL7100776A (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2318650A1 (de) * 1972-04-15 1973-10-31 Takeda Chemical Industries Ltd Verfahren zur herstellung von deacetylcephalosporin c

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS577719B2 (OSRAM) * 1973-09-28 1982-02-12
JPS577720B2 (OSRAM) * 1973-10-01 1982-02-12
US4520101A (en) * 1983-03-07 1985-05-28 Bristol-Myers Company Production of cephalosporin C
WO1990012110A1 (en) * 1989-04-04 1990-10-18 Biopure Corporation Enzymatic production of 7-amino cephalosporanic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139388A (en) * 1963-01-04 1964-06-30 Olin Mathieson Method of producing cephalosporinc
US3139389A (en) * 1963-01-04 1964-06-30 Olin Mathieson Method of producing cephalosporin c
FR1429873A (fr) * 1964-04-10 1966-02-25 Nat Res Dev Procédé de production de céphalosporines antibiotiques

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2318650A1 (de) * 1972-04-15 1973-10-31 Takeda Chemical Industries Ltd Verfahren zur herstellung von deacetylcephalosporin c

Also Published As

Publication number Publication date
NL7100776A (OSRAM) 1971-07-23
FR2081445A1 (OSRAM) 1971-12-03
FR2081445B1 (OSRAM) 1975-01-17
CH553850A (de) 1974-09-13
US3776815A (en) 1973-12-04
GB1335264A (en) 1973-10-24

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