DE2031227A1 - Neue substituierte Sahcylsauren und Verfahren zu ihrer Herstellung - Google Patents

Neue substituierte Sahcylsauren und Verfahren zu ihrer Herstellung

Info

Publication number
DE2031227A1
DE2031227A1 DE19702031227 DE2031227A DE2031227A1 DE 2031227 A1 DE2031227 A1 DE 2031227A1 DE 19702031227 DE19702031227 DE 19702031227 DE 2031227 A DE2031227 A DE 2031227A DE 2031227 A1 DE2031227 A1 DE 2031227A1
Authority
DE
Germany
Prior art keywords
lower alkyl
acid
alkyl
amino
alkylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702031227
Other languages
German (de)
English (en)
Inventor
Tsung Ying Walford Gordon Lyn Witzel Bruce Edward Westfield Jones Howard Matawan NJ Shen (V St A )
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2031227A1 publication Critical patent/DE2031227A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19702031227 1969-06-25 1970-06-24 Neue substituierte Sahcylsauren und Verfahren zu ihrer Herstellung Pending DE2031227A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83662369A 1969-06-25 1969-06-25
US3032270A 1970-04-20 1970-04-20

Publications (1)

Publication Number Publication Date
DE2031227A1 true DE2031227A1 (de) 1971-01-07

Family

ID=26705913

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702031227 Pending DE2031227A1 (de) 1969-06-25 1970-06-24 Neue substituierte Sahcylsauren und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
JP (1) JPS4920197B1 (enExample)
CH (1) CH536278A (enExample)
DE (1) DE2031227A1 (enExample)
FR (1) FR2053015A1 (enExample)
GB (1) GB1268465A (enExample)
NL (1) NL7008623A (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003199A1 (en) * 1984-11-29 1986-06-05 Italfarmaco S.P.A. Amino-salicylic acid derivatives and pharmaceutical compositions
WO1986005485A1 (en) * 1985-03-14 1986-09-25 Smith Kline Dauelsberg Gmbh Amides of non-steroidal anti-inflammatory carboxylic acids
WO2001079153A1 (en) * 2000-04-19 2001-10-25 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US6573402B1 (en) 2000-04-20 2003-06-03 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US7189878B2 (en) 2002-06-19 2007-03-13 Neurotech Co., Ltd. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
US8455470B2 (en) 2006-04-13 2013-06-04 Neurotech Pharmaceuticals Co., Ltd Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases
US8686185B2 (en) 2007-11-12 2014-04-01 Neurotech Pharmaceuticals Co., Ltd. Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5283169U (enExample) * 1975-12-18 1977-06-21
FR2405241A1 (fr) * 1977-10-06 1979-05-04 Rorer Inc William H Benzylideneaniline et ses derives, utilises pour le traitement d'inflammation chez les animaux a sang chaud
IT1244873B (it) * 1990-09-12 1994-09-12 Depha Team Srl Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali
KR100668111B1 (ko) 2005-07-28 2007-01-12 (주)에스에이치제약 강력한 항산화 효과를 가짐으로써 급성 및 퇴행성 뇌신경계질환의 예방 및 치료에 이용 가능한 신규물질인아미노살리실산 유도체와 그 염의 제조방법
KR100639551B1 (ko) 2005-07-28 2006-10-30 (주)에스에이치제약 5-(치환된 페닐알킬)아미노살리실산 화합물의 제조 방법
US20220249343A1 (en) * 2019-07-08 2022-08-11 Gnt Pharma Co., Ltd. Cosmetic composition including 5-benzylaminosalicylic acid derivative, and topical use thereof

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003199A1 (en) * 1984-11-29 1986-06-05 Italfarmaco S.P.A. Amino-salicylic acid derivatives and pharmaceutical compositions
WO1986005485A1 (en) * 1985-03-14 1986-09-25 Smith Kline Dauelsberg Gmbh Amides of non-steroidal anti-inflammatory carboxylic acids
US4783487A (en) * 1985-03-14 1988-11-08 Smith Kline Dauelsberg Gmbh N-(1-carboxy-2-hydroxy-5-phenyl)-2-(6-methoxy-2-naphthyl)propionamide and anti-inflammatory use thereof
JPH0755921B2 (ja) * 1985-03-14 1995-06-14 スミス・クライン・ダウエルスベルク・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング アミド類
WO2001079153A1 (en) * 2000-04-19 2001-10-25 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US8211878B2 (en) 2000-04-20 2012-07-03 Neurotech Pharmaceuticals Co., Ltd. Method for reducing neuronal death in nervous system injuries resulting from amyotrophic lateral sclerosis
US6964982B2 (en) 2000-04-20 2005-11-15 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US7750045B2 (en) 2000-04-20 2010-07-06 Neurotech Pharmaceuticals Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US6573402B1 (en) 2000-04-20 2003-06-03 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US8211877B2 (en) 2000-04-20 2012-07-03 Neurotech Pharmaceuticals Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
US7189878B2 (en) 2002-06-19 2007-03-13 Neurotech Co., Ltd. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
US7319160B2 (en) 2002-06-19 2008-01-15 Amkor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
US7371896B2 (en) 2002-06-19 2008-05-13 Amkor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
US7511074B2 (en) 2002-06-19 2009-03-31 Amkor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
US8455470B2 (en) 2006-04-13 2013-06-04 Neurotech Pharmaceuticals Co., Ltd Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases
US8598383B2 (en) 2006-04-13 2013-12-03 Neurotech Pharmaceuticals Co., Ltd. Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases
US8686185B2 (en) 2007-11-12 2014-04-01 Neurotech Pharmaceuticals Co., Ltd. Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts

Also Published As

Publication number Publication date
CH536278A (de) 1973-04-30
JPS4920197B1 (enExample) 1974-05-23
FR2053015A1 (enExample) 1971-04-16
NL7008623A (enExample) 1970-12-29
GB1268465A (en) 1972-03-29

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