DE19539493A1 - Starker homologer Promotor aus Hamster - Google Patents
Starker homologer Promotor aus HamsterInfo
- Publication number
- DE19539493A1 DE19539493A1 DE19539493A DE19539493A DE19539493A1 DE 19539493 A1 DE19539493 A1 DE 19539493A1 DE 19539493 A DE19539493 A DE 19539493A DE 19539493 A DE19539493 A DE 19539493A DE 19539493 A1 DE19539493 A1 DE 19539493A1
- Authority
- DE
- Germany
- Prior art keywords
- promoter
- sequence
- gene
- nucleic acid
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19539493A DE19539493A1 (de) | 1995-10-24 | 1995-10-24 | Starker homologer Promotor aus Hamster |
| ES96937224T ES2281905T3 (es) | 1995-10-24 | 1996-10-24 | Promotor homologo intenso obtenido de hamster. |
| DK96937224T DK0857211T3 (da) | 1995-10-24 | 1996-10-24 | Stærk homolog promoter fra hamster |
| EP96937224A EP0857211B1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
| US09/051,969 US6063598A (en) | 1995-10-24 | 1996-10-24 | Strong homologous promoter obtained from hamsters |
| PCT/EP1996/004631 WO1997015664A1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
| AT96937224T ATE355370T1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
| PT96937224T PT857211E (pt) | 1995-10-24 | 1996-10-24 | Promotor homólogo forte obtido a partir de hamster |
| DE59611420T DE59611420D1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
| EP06126019A EP1803815A3 (de) | 1995-10-24 | 1996-10-24 | Starker homologer Promotor aus Hamster |
| CA002234071A CA2234071C (en) | 1995-10-24 | 1996-10-24 | Intensive homologous promoter obtained from hamsters |
| JP51628897A JP3966903B2 (ja) | 1995-10-24 | 1996-10-24 | ハムスターの強力な同種プロモーター |
| MX9802764A MX9802764A (es) | 1995-10-24 | 1998-04-07 | Promotor homologo fuerte procedente de un hamster. |
| JP2006187719A JP2006320330A (ja) | 1995-10-24 | 2006-07-07 | ハムスターのユビキチン遺伝子 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19539493A DE19539493A1 (de) | 1995-10-24 | 1995-10-24 | Starker homologer Promotor aus Hamster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19539493A1 true DE19539493A1 (de) | 1997-04-30 |
Family
ID=7775593
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19539493A Ceased DE19539493A1 (de) | 1995-10-24 | 1995-10-24 | Starker homologer Promotor aus Hamster |
| DE59611420T Expired - Lifetime DE59611420D1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE59611420T Expired - Lifetime DE59611420D1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6063598A (https=) |
| EP (2) | EP0857211B1 (https=) |
| JP (2) | JP3966903B2 (https=) |
| AT (1) | ATE355370T1 (https=) |
| CA (1) | CA2234071C (https=) |
| DE (2) | DE19539493A1 (https=) |
| DK (1) | DK0857211T3 (https=) |
| ES (1) | ES2281905T3 (https=) |
| MX (1) | MX9802764A (https=) |
| PT (1) | PT857211E (https=) |
| WO (1) | WO1997015664A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10256083A1 (de) * | 2002-11-29 | 2004-08-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen |
| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998032869A1 (en) * | 1997-01-29 | 1998-07-30 | Neurosearch A/S | Expression vectors and methods for in vivo expression of therapeutic polypeptides |
| JP2004516016A (ja) * | 2000-09-18 | 2004-06-03 | ジェンザイム・コーポレイション | ハイブリッドユビキチンプロモーターを含む発現ベクター |
| EP1624067A3 (en) * | 2000-09-18 | 2006-03-15 | Genzyme Corporation | Expression vectors containing hybrid ubiquitin promoters |
| PT1600510E (pt) * | 2001-07-04 | 2007-06-25 | Chromagenics Bv | Sequências de adn com actividade anti-repressora. |
| US7344886B2 (en) * | 2002-11-29 | 2008-03-18 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product |
| DE10338531A1 (de) | 2003-08-19 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Reklonierung von Produktionszellen |
| US8669109B2 (en) | 2003-08-19 | 2014-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methods of producing proteins in Chinese hamster ovary (CHO) cells |
| US20050101017A1 (en) * | 2003-11-10 | 2005-05-12 | Wojtek Auerbach | Method of improving gene targeting using a ubiquitin promoter |
| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| US9163257B2 (en) * | 2005-06-20 | 2015-10-20 | Cadila Healthcare Limited | Expression vector and methods of producing high levels of proteins |
| EP1806365A1 (en) | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
| US20080124760A1 (en) | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
| RS63930B1 (sr) | 2011-10-28 | 2023-02-28 | Prothena Biosciences Ltd | Humanizovana antitela koja prepoznaju alfa-sinuklein |
| DK2807188T3 (da) | 2012-01-27 | 2019-10-07 | Prothena Biosciences Ltd | Humaniserede antistoffer, der genkender alpha-synuclein |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| EP2938726B1 (en) | 2012-12-31 | 2017-09-27 | Boehringer Ingelheim International GmbH | Heterologous intron within a signal peptide |
| WO2014102101A1 (en) | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Novel intron sequences |
| US10501531B2 (en) | 2013-03-13 | 2019-12-10 | Prothena Biosciences Limited | Tau immunotherapy |
| US9989540B2 (en) | 2013-05-10 | 2018-06-05 | The Regents Of The University Of California | Diagnostic and monitoring system for Huntington's disease |
| US10513555B2 (en) | 2013-07-04 | 2019-12-24 | Prothena Biosciences Limited | Antibody formulations and methods |
| WO2015004633A1 (en) | 2013-07-12 | 2015-01-15 | Neotope Biosciences Limited | Antibodies that recognize islet-amyloid polypeptide (iapp) |
| US9850302B2 (en) | 2013-07-12 | 2017-12-26 | Prothena Biosciences Limited | Antibodies that recognize IAPP |
| JP2017501848A (ja) | 2013-11-19 | 2017-01-19 | プロセナ バイオサイエンシーズ リミテッド | 便秘症状からのレビー小体病の免疫療法のモニター |
| DK3089760T3 (da) | 2013-12-31 | 2020-03-16 | Proteonic Biotechnology Ip B V | Konstrukt og sekvens til forbedret genekspression |
| JP2017514458A (ja) | 2014-03-12 | 2017-06-08 | プロセナ バイオサイエンシーズ リミテッド | Ｌｇ４−５に対して特異的な抗−ラミニン４抗体 |
| KR20160131082A (ko) | 2014-03-12 | 2016-11-15 | 프로테나 바이오사이언시즈 리미티드 | Lg1-3에 특이적인 항-라미닌4 항체 |
| PT3116911T (pt) | 2014-03-12 | 2019-09-04 | Prothena Biosciences Ltd | Anticorpos anti-mcam e métodos de utilização associados |
| TW201623331A (zh) | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法 |
| CA2944402A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| EP3230309B1 (en) | 2014-12-10 | 2023-03-29 | OPKO Biologics Ltd. | Methods of producing long acting ctp-modified growth hormone polypeptides |
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-
1995
- 1995-10-24 DE DE19539493A patent/DE19539493A1/de not_active Ceased
-
1996
- 1996-10-24 EP EP96937224A patent/EP0857211B1/de not_active Expired - Lifetime
- 1996-10-24 ES ES96937224T patent/ES2281905T3/es not_active Expired - Lifetime
- 1996-10-24 DK DK96937224T patent/DK0857211T3/da active
- 1996-10-24 US US09/051,969 patent/US6063598A/en not_active Expired - Lifetime
- 1996-10-24 DE DE59611420T patent/DE59611420D1/de not_active Expired - Lifetime
- 1996-10-24 JP JP51628897A patent/JP3966903B2/ja not_active Expired - Lifetime
- 1996-10-24 PT PT96937224T patent/PT857211E/pt unknown
- 1996-10-24 EP EP06126019A patent/EP1803815A3/de not_active Withdrawn
- 1996-10-24 CA CA002234071A patent/CA2234071C/en not_active Expired - Lifetime
- 1996-10-24 WO PCT/EP1996/004631 patent/WO1997015664A1/de not_active Ceased
- 1996-10-24 AT AT96937224T patent/ATE355370T1/de active
-
1998
- 1998-04-07 MX MX9802764A patent/MX9802764A/es active IP Right Grant
-
2006
- 2006-07-07 JP JP2006187719A patent/JP2006320330A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10256083A1 (de) * | 2002-11-29 | 2004-08-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen |
| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11513572A (ja) | 1999-11-24 |
| MX9802764A (es) | 1998-11-30 |
| EP0857211A1 (de) | 1998-08-12 |
| US6063598A (en) | 2000-05-16 |
| PT857211E (pt) | 2007-03-30 |
| WO1997015664A1 (de) | 1997-05-01 |
| DE59611420D1 (de) | 2007-04-12 |
| CA2234071A1 (en) | 1997-05-01 |
| ATE355370T1 (de) | 2006-03-15 |
| EP1803815A2 (de) | 2007-07-04 |
| CA2234071C (en) | 2003-01-21 |
| EP1803815A3 (de) | 2007-08-29 |
| EP0857211B1 (de) | 2007-02-28 |
| JP3966903B2 (ja) | 2007-08-29 |
| ES2281905T3 (es) | 2007-10-01 |
| DK0857211T3 (da) | 2007-03-26 |
| JP2006320330A (ja) | 2006-11-30 |
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