DE1695295C2 - Morpholinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen - Google Patents

Morpholinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE1695295C2
DE1695295C2 DE1695295A DEJ0035099A DE1695295C2 DE 1695295 C2 DE1695295 C2 DE 1695295C2 DE 1695295 A DE1695295 A DE 1695295A DE J0035099 A DEJ0035099 A DE J0035099A DE 1695295 C2 DE1695295 C2 DE 1695295C2
Authority
DE
Germany
Prior art keywords
parts
morpholine
pharmaceutical compositions
morpholine derivatives
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1695295A
Other languages
German (de)
English (en)
Other versions
DE1695295A1 (de
Inventor
Keith Blakeney Mallion
Alexander Henry Macclesfield Cheshire Todd
Ralph William Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE1695295A1 publication Critical patent/DE1695295A1/de
Application granted granted Critical
Publication of DE1695295C2 publication Critical patent/DE1695295C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1695295A 1966-12-28 1967-11-24 Morpholinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen Expired DE1695295C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB57963/66A GB1138405A (en) 1966-12-28 1966-12-28 Morpholine derivatives
GB5796367 1966-12-28

Publications (2)

Publication Number Publication Date
DE1695295A1 DE1695295A1 (de) 1975-03-20
DE1695295C2 true DE1695295C2 (de) 1984-01-05

Family

ID=26267707

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1695295A Expired DE1695295C2 (de) 1966-12-28 1967-11-24 Morpholinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Country Status (7)

Country Link
US (1) US3714161A (enExample)
BE (1) BE708557A (enExample)
CH (1) CH504452A (enExample)
DE (1) DE1695295C2 (enExample)
FR (2) FR1571341A (enExample)
GB (1) GB1138405A (enExample)
NL (1) NL157303B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901032A1 (de) * 1978-01-20 1979-08-02 Erba Farmitalia Substituierte propanolamin- und morpholin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959273A (en) * 1966-12-28 1976-05-25 Imperial Chemical Industries Limited Morpholine derivatives
US3857839A (en) * 1969-06-20 1974-12-31 Ici Ltd For cyclising 1-aryloxy-3 beta-substituted ethylamino-2-propanols
BE758766A (fr) * 1969-11-17 1971-05-10 Ici Ltd Nouveaux derives de la morpholine et de la
BE759013R (fr) * 1969-11-17 1971-05-17 Ici Ltd Derives de la
US3806595A (en) * 1971-08-09 1974-04-23 Ici Ltd Method of producing anorexia
GB1382526A (en) * 1972-08-11 1975-02-05 Ici Ltd Morpholine derivatives
US4033951A (en) * 1973-12-13 1977-07-05 Imperial Chemical Industries Limited Morpholine derivative of a 1,4-benzothiazin-3-one
US4079135A (en) * 1973-12-13 1978-03-14 Imperial Chemical Industries Limited Morpholine derivatives as antidepressants
US4109088A (en) * 1975-01-29 1978-08-22 Yamanouchi Pharmaceutical Co., Ltd. 2-(indenyloxymethyl) morpholine derivatives
CA1064927A (en) * 1975-01-29 1979-10-23 Yuji Kawashima Process of producing 2-(indenyloxymethyl) morpholine derivatives
DE2530860C2 (de) * 1975-07-10 1987-01-15 Yoshitomi Pharmaceutical Industries, Ltd., Osaka 2-[2-(2-Thenyl)-phenoxymethyl]-morpholin-Derivate
US4005084A (en) * 1975-07-10 1977-01-25 Yoshitomi Pharmaceutical Industries, Ltd. Thienylmethyl phenoxy morpholine compounds
US4241059A (en) * 1979-12-17 1980-12-23 E. R. Squibb & Sons, Inc. 6-[(Aryloxy)methyl]-2-morpholinemethanol derivatives and use thereof
FR2534915B1 (fr) * 1982-10-26 1985-10-25 Lafon Labor Nouveaux derives de 2-(phenoxymethyl)-morpholine, utilisation en therapeutique et procede de preparation
FR2575158B1 (fr) * 1984-12-20 1987-10-02 Pf Medicament Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central
FR2612926B1 (fr) * 1987-03-24 1989-06-09 Adir Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant
AU3364493A (en) * 1992-01-28 1993-09-01 Smithkline Beecham Plc Compounds as calcium channel antagonists
WO1994018182A1 (fr) * 1993-02-10 1994-08-18 Yamanouchi Pharmaceutical Co., Ltd. Derive de morpholine
AU2001290873B2 (en) 2000-09-11 2006-07-27 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
EA200601798A1 (ru) * 2004-04-30 2007-04-27 Уорнер-Ламберт Компани Ллс Замещенные соединения морфолина для лечения расстройств центральной нервной системы
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
DK2076508T3 (da) 2006-10-18 2011-02-21 Pfizer Prod Inc Biaryl-ether-urinstof-forbindelser
CA2735934C (en) 2008-09-05 2014-01-07 Supernus Pharmaceuticals, Inc. Method of treatment of attention deficit/hyperactivity disorder (adhd)
MX355697B (es) 2010-04-12 2018-04-27 Supernus Pharmaceuticals Inc Métodos para producir sales de viloxazina y polimorfos novedosos de las mismas.
AU2011255276B2 (en) 2010-05-21 2016-09-22 Research Triangle Institute Phenylmorpholines and analogues thereof
EP2571859B1 (en) 2010-05-21 2015-07-22 Research Triangle Institute 1-phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
AU2013217013B2 (en) 2012-02-08 2017-04-20 Supernus Pharmaceuticals, Inc. Modified release formulations of viloxazine
EP4317141A1 (en) 2022-08-04 2024-02-07 Curia Spain S.A.U. Process and intermediates for the preparation of viloxazine and other 2-substituted morpholine derivatives
WO2025219523A1 (en) 2024-04-19 2025-10-23 Cambrex Profarmaco Milano S.R.L. "intermediates and processes for the preparation of viloxazine"

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH356451A (de) * 1957-04-05 1961-08-31 Geigy Ag J R Verfahren zur Herstellung von neuen Morpholinverbindungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901032A1 (de) * 1978-01-20 1979-08-02 Erba Farmitalia Substituierte propanolamin- und morpholin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Also Published As

Publication number Publication date
GB1138405A (en) 1969-01-01
NL6717719A (enExample) 1968-07-01
FR1571341A (enExample) 1969-06-20
DE1695295A1 (de) 1975-03-20
FR7557M (enExample) 1969-12-29
US3714161A (en) 1973-01-30
BE708557A (enExample) 1968-06-27
NL157303B (nl) 1978-07-17
CH504452A (de) 1971-03-15

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Legal Events

Date Code Title Description
8126 Change of the secondary classification

Ipc: A61K 31/535

D2 Grant after examination
8364 No opposition during term of opposition