ES2142397T3 - Derivado de morfolina. - Google Patents

Derivado de morfolina.

Info

Publication number
ES2142397T3
ES2142397T3 ES94905865T ES94905865T ES2142397T3 ES 2142397 T3 ES2142397 T3 ES 2142397T3 ES 94905865 T ES94905865 T ES 94905865T ES 94905865 T ES94905865 T ES 94905865T ES 2142397 T3 ES2142397 T3 ES 2142397T3
Authority
ES
Spain
Prior art keywords
morpholine
derivative
reincorporation
anxiety
depression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94905865T
Other languages
English (en)
Inventor
Mitsuo Fujii
Takayuki Suzuki
Satoshi Hayashibe
Shin-Ichi Tsukamoto
Shin-Ichi Yatsugi
Tokio Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2142397T3 publication Critical patent/ES2142397T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

UN DERIVADO DE LA MORFOLINA REPRESENTADO POR LA FORMULA GENERAL (I) O SAL DEL MISMO, EN LA QUE R{SUP,1} Y R{SUP,3} PUEDEN SER LO MISMO O DIFERENTES UNO DE OTRO Y CADA UNO REPRESENTA HIDROGENO O ALQUILO BAJO; R{SUP,2} REPRESENTA HALOGENO, Y LA LINEA QUEBRADA REPRESENTA UN DOBLE ENLACE OPCIONAL. EL COMPUESTO Y SALES DEL MISMO TIENEN LAS ACTIVIDADES DE UN INHIBIDOR DE REINCORPORACION 5-HT Y DE UN ANTAGONISTA RECEPTOR 5-HT{SUB,2} Y SON UTILES COMO AGENTES TERAPEUTICOS REDUCTORES DE EFECTOS COLATERALES COMO LA DEPRESION Y LA ANSIEDAD.
ES94905865T 1993-02-10 1994-02-08 Derivado de morfolina. Expired - Lifetime ES2142397T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4569193 1993-02-10
JP24014793 1993-09-27

Publications (1)

Publication Number Publication Date
ES2142397T3 true ES2142397T3 (es) 2000-04-16

Family

ID=26385743

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94905865T Expired - Lifetime ES2142397T3 (es) 1993-02-10 1994-02-08 Derivado de morfolina.

Country Status (18)

Country Link
US (1) US5521180A (es)
EP (1) EP0684237B1 (es)
KR (1) KR100302819B1 (es)
CN (1) CN1042028C (es)
AT (1) ATE187448T1 (es)
AU (1) AU670675B2 (es)
CA (1) CA2155183A1 (es)
DE (1) DE69422021T2 (es)
DK (1) DK0684237T3 (es)
ES (1) ES2142397T3 (es)
FI (1) FI953793A (es)
GR (1) GR3032816T3 (es)
HU (1) HU220383B (es)
NO (1) NO305170B1 (es)
PT (1) PT684237E (es)
TW (1) TW397829B (es)
UA (1) UA41350C2 (es)
WO (1) WO1994018182A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6337328B1 (en) * 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
AU9087301A (en) * 2000-09-11 2002-03-26 Sepracor Inc Ligands for monoamine receptors and transporters, and methods of use thereof
JP2005034165A (ja) * 2002-06-26 2005-02-10 Mu-Hyun Cho マット一体型のストーンベッド
AU2005260955A1 (en) * 2004-07-14 2006-01-19 Astellas Pharma Inc. Agent for promoting the recovery from dysfunction after the onset of central neurological disease
TW200846003A (en) * 2007-03-15 2008-12-01 Astellas Pharma Inc Novel prophylactic and/or therapeutic agent for diabetic neuropathy
TW200846002A (en) * 2007-03-15 2008-12-01 Astellas Pharma Inc Novel prophylactic and/or therapeutic agent for diabetic neuropathy
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
KR101165996B1 (ko) 2010-04-23 2012-07-18 주식회사 녹십자 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138405A (en) * 1966-12-28 1969-01-01 Ici Ltd Morpholine derivatives
JPS5283773A (en) * 1976-01-01 1977-07-12 Yamanouchi Pharmaceut Co Ltd Novel indene derivative
JPS52111580A (en) * 1976-03-15 1977-09-19 Yamanouchi Pharmaceut Co Ltd Novel indene derivatives and salts thereof
JPS55113717A (en) * 1979-02-24 1980-09-02 Yamanouchi Pharmaceut Co Ltd Antidepressive drug
JPS61145119A (ja) * 1984-12-19 1986-07-02 Yamanouchi Pharmaceut Co Ltd 脳障害による精神症状の改善，治療剤
AU5136385A (en) * 1984-12-20 1986-07-17 Medicament P.F 2-arylalkyloxymethyl-morpholine derivatives
GB2177085A (en) * 1985-06-18 1987-01-14 Ici Plc Fungicidal compounds and compositions

Also Published As

Publication number Publication date
UA41350C2 (uk) 2001-09-17
AU670675B2 (en) 1996-07-25
GR3032816T3 (en) 2000-06-30
NO305170B1 (no) 1999-04-12
EP0684237A1 (en) 1995-11-29
KR100302819B1 (ko) 2001-11-22
FI953793A0 (fi) 1995-08-10
ATE187448T1 (de) 1999-12-15
CA2155183A1 (en) 1994-08-18
CN1117729A (zh) 1996-02-28
EP0684237B1 (en) 1999-12-08
DE69422021T2 (de) 2000-07-13
NO953118L (no) 1995-10-10
AU5980094A (en) 1994-08-29
DE69422021D1 (en) 2000-01-13
TW397829B (en) 2000-07-11
HU220383B (hu) 2002-01-28
EP0684237A4 (en) 1996-02-14
PT684237E (pt) 2000-04-28
US5521180A (en) 1996-05-28
HUT72674A (en) 1996-05-28
FI953793A (fi) 1995-08-10
WO1994018182A1 (en) 1994-08-18
CN1042028C (zh) 1999-02-10
HU9502359D0 (en) 1995-10-30
NO953118D0 (no) 1995-08-09
DK0684237T3 (da) 2000-05-08

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