DE1668661C3 - 6-Cyansteroide und Verfahren zu deren Herstellung - Google Patents

6-Cyansteroide und Verfahren zu deren Herstellung

Info

Publication number
DE1668661C3
DE1668661C3 DE1668661A DE1668661A DE1668661C3 DE 1668661 C3 DE1668661 C3 DE 1668661C3 DE 1668661 A DE1668661 A DE 1668661A DE 1668661 A DE1668661 A DE 1668661A DE 1668661 C3 DE1668661 C3 DE 1668661C3
Authority
DE
Germany
Prior art keywords
chloroethylthio
pregnadiene
acetate
cyano
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1668661A
Other languages
German (de)
English (en)
Other versions
DE1668661B2 (de
DE1668661A1 (de
Inventor
Alberto Consonni
Roberto Mailand Sciaky (Italien)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of DE1668661A1 publication Critical patent/DE1668661A1/de
Publication of DE1668661B2 publication Critical patent/DE1668661B2/de
Application granted granted Critical
Publication of DE1668661C3 publication Critical patent/DE1668661C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1668661A 1967-02-07 1968-02-02 6-Cyansteroide und Verfahren zu deren Herstellung Expired DE1668661C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1233267 1967-02-07

Publications (3)

Publication Number Publication Date
DE1668661A1 DE1668661A1 (de) 1971-09-30
DE1668661B2 DE1668661B2 (de) 1973-05-17
DE1668661C3 true DE1668661C3 (de) 1973-12-13

Family

ID=11139672

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1668661A Expired DE1668661C3 (de) 1967-02-07 1968-02-02 6-Cyansteroide und Verfahren zu deren Herstellung

Country Status (9)

Country Link
US (1) US3513161A (US20020051482A1-20020502-M00012.png)
BE (1) BE710410A (US20020051482A1-20020502-M00012.png)
CH (1) CH512457A (US20020051482A1-20020502-M00012.png)
DE (1) DE1668661C3 (US20020051482A1-20020502-M00012.png)
DK (1) DK116657B (US20020051482A1-20020502-M00012.png)
FR (1) FR7339M (US20020051482A1-20020502-M00012.png)
GB (1) GB1169134A (US20020051482A1-20020502-M00012.png)
NL (2) NL6801283A (US20020051482A1-20020502-M00012.png)
SE (1) SE325569B (US20020051482A1-20020502-M00012.png)

Also Published As

Publication number Publication date
DK116657B (da) 1970-02-02
DE1668661B2 (de) 1973-05-17
NL135951C (US20020051482A1-20020502-M00012.png)
US3513161A (en) 1970-05-19
BE710410A (US20020051482A1-20020502-M00012.png) 1968-08-06
NL6801283A (US20020051482A1-20020502-M00012.png) 1968-08-08
FR7339M (US20020051482A1-20020502-M00012.png) 1969-10-13
SE325569B (US20020051482A1-20020502-M00012.png) 1970-07-06
GB1169134A (en) 1969-10-29
CH512457A (de) 1971-09-15
DE1668661A1 (de) 1971-09-30

Similar Documents

Publication Publication Date Title
DE2323215C3 (de) Pregna-l,4-dien-ll-ol-3,20-dione, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
DE2323216A1 (de) Verfahren zur auftrennung von stereoisomerengemischen von steroiden
WO1994022899A1 (de) Neue prednisolonderivate
DD202034A5 (de) Verfahren zur herstellung von 4-pregnenderivaten
DE3336292C2 (US20020051482A1-20020502-M00012.png)
DE1253708B (de) Verfahren zur Herstellung von delta 16-20-Ketosteroiden
DE1668661C3 (de) 6-Cyansteroide und Verfahren zu deren Herstellung
DE2852055C2 (US20020051482A1-20020502-M00012.png)
DE1618993B1 (de) Verfahren zur Herstellung von 3-(2'-Chloräthylthio)-6-formyl-steroiden
DE1643033B2 (de) 9 alpha, 11 beta-dichlor-16 alpha- methyl-1,4-pregnadien-17 alpha, 21-diol- 3,20-dion-17-ester verfahren zu ihrer herstellung und sie enthaltende therapeutische zubereitungen
DE1568308B2 (de) Verfahren zur herstellung von delta hoch 4,9,11-trienen der 19-nor- androstanreihe, 17-oxygenierte 3-oxo- 7 alpha-methyl-delta hoch 4,9,11-19 nor- androstatriene und diese enthaltende pharmazeutische praeparate sowie 3-oxo-7 alpha -methyl-delta hoch 5 (10), 9 (11) -19-nor- androstadiene
DE1807585C3 (de) 14,15beta-Epoxycardenolide, Verfahren zu deren Herstellung und diese enthaltende Mittel
DE1188079B (de) Verfahren zur Herstellung von 17alpha, 21-Dioxysteroiden
DE1468893A1 (de) Verfahren zur Herstellung von 21-Estern von Pregnanderivaten
DE2819480C2 (US20020051482A1-20020502-M00012.png)
DE1921462C3 (de) Steroid oxazoline, Verfahren zu deren Herstellung und dieselben ent haltende Arzneimittel
DE1668685C3 (de) 17-Hydroxy- und 17-Acyloxy-6 beta, 7 beta-epoxy-1 alpha, 2 alpha-methylen-4-pregnen-3,20-dione, Verfahren zu deren Herstellung sowie diese enthaltende Mittel
EP0186834B1 (de) 13alpha-Alkyl-17beta-(3-acyloxy-propyl)-gonane
DE2109305B2 (de) 20-Hydroxylierte 17 a - MethyI-19-nor-pregna-4,9diene, Verfahren zu deren Herstellung sowie Zwischenprodukte
DE1468892C (de) Verfahren zur Herstellung von Steroid-21-apocarnphan-l' -carboxylaten mit lokaler antiinflammatorischer Wirkung
DE1806158C3 (de) 21-Ester von Steroiden, Verfahren zu deren Herstellung sowie diese enthaltende pharmazeutische Zubereitungen
DE1618993C (de) Verfahren zur Herstellung von 3-(2-Chloräthylthio)-6-formyl-steroiden
AT232659B (de) Verfahren zur Herstellung neuer Steroidverbindungen
AT292210B (de) Verfahren zur Herstellung von neuen in 2-Stellung durch Chlor substituierten Steroiden der Pregnanreihe
DE1802962C3 (de) Neue Galpha, 6beta-Dlfluorsteroide, Verfahren zu ihrer Herstellung, sowie diese enthaltende Mittel

Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)