DE1593782B2 - 1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate - Google Patents
1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparateInfo
- Publication number
- DE1593782B2 DE1593782B2 DE1967B0093025 DEB0093025A DE1593782B2 DE 1593782 B2 DE1593782 B2 DE 1593782B2 DE 1967B0093025 DE1967B0093025 DE 1967B0093025 DE B0093025 A DEB0093025 A DE B0093025A DE 1593782 B2 DE1593782 B2 DE 1593782B2
- Authority
- DE
- Germany
- Prior art keywords
- formula
- tert
- choh
- compounds
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (59)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL136601D NL136601C (sv) | 1967-06-15 | ||
DE1967B0093025 DE1593782B2 (de) | 1967-06-15 | 1967-06-15 | 1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
FR1583559D FR1583559A (sv) | 1967-06-15 | 1967-06-17 | |
US700376A US3541130A (en) | 1967-02-06 | 1968-01-25 | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
JP43038048A JPS51100B1 (sv) | 1967-06-15 | 1968-06-05 | |
ES354823A ES354823A1 (es) | 1967-06-15 | 1968-06-08 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-ter-butilamino propanos sustituidos. |
NL6808196A NL6808196A (sv) | 1967-06-15 | 1968-06-11 | |
YU135068A YU33262B (en) | 1967-06-15 | 1968-06-12 | Postopek za pripravo novih substiturnih 1-fenoksi -2-hidroksi-3-terc. butilamino-propanov |
CH1168170A CH509973A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
CH876668A CH495950A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
CH1167670A CH509254A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
CH1167970A CH509257A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
CH1167870A CH509256A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
CH1167770A CH509255A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
SE07980/68A SE355571B (sv) | 1967-06-15 | 1968-06-13 | |
CH1167570A CH509253A (de) | 1967-06-15 | 1968-06-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
AT247770A AT289076B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
FI681664A FI48922C (sv) | 1967-06-15 | 1968-06-14 | Förfarande för framställning av farmaceutiskt verksamma nya, både rase miska och optiskt aktiva substituerade 1-fenoxi-2-hydroxi-3-tert.butyl aminopropaner och dessa salter. |
AT247870A AT289077B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
IE710/68A IE32373B1 (en) | 1967-06-15 | 1968-06-14 | Propanolamine derivatives |
BE716647D BE716647A (sv) | 1967-06-15 | 1968-06-14 | |
AT572568A AT289067B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
AT248370A AT289082B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
AT248170A AT289080B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
AT248070A AT289079B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy-oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.-butylaminopropanen und deren Salzen |
DK281968AA DK127059B (da) | 1967-06-15 | 1968-06-14 | Analogifremgangsmåde til fremstilling af substituerede 1-phenoxy-2-hydroxy-3-tert.butylaminopropaner eller salte heraf eller de tilsvarende optisk aktive antipoder. |
IL6830181A IL30181A (en) | 1967-06-15 | 1968-06-14 | 1-(substituted phenoxy)-2-hydroxy-3-tertiary butylaminopropanes,their preparation and pharmaceutical compositions containing them |
AT248270A AT289081B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
GB28529/68A GB1187546A (en) | 1967-06-15 | 1968-06-14 | Propanolamine derivatives |
AT247970A AT289078B (de) | 1967-06-15 | 1968-06-14 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Nitrilophenoxy- oder 1-Alkinyloxyphenoxy-2-hydroxy-3-tert.butylaminopropanen und deren Salzen |
BG011629A BG15039A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови заместени 1-фенокси-2-хидрокси- -3-терц.бутиламинопропани и техните соли |
BG011631A BG15041A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови заместени 1-фенокси 2-хидрокси-3-терц. бутиламино-пропани и техните соли |
BG011627A BG15037A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови заместени 1-фенокси-2-хидрокси- -3-терц. бутиламинопропани и техните соли |
BG011632A BG15042A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови-заместени 1-фенокси-2-хидрокси-3-терц. бутиламино пропани и техните соли |
BG011628A BG15038A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови заместени 1-фенокси -2- хидрокси -3- терц.бутиламинопропани и техните соли |
BG011630A BG15040A3 (bg) | 1967-06-15 | 1968-06-15 | Метод за получаване на нови заместени 1-фенокси-2-хидрокси -3-терц.бутиламинопропани и техните соли |
FR166464A FR8162M (sv) | 1967-06-15 | 1968-09-17 | |
ES368398A ES368398A1 (es) | 1967-06-15 | 1969-06-16 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-ter-butilaminopropanos sustituidos. |
ES368395A ES368395A1 (es) | 1967-06-15 | 1969-06-16 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-ter-butilaminopropanos sustituidos. |
ES368401A ES368401A1 (es) | 1967-06-15 | 1969-06-16 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-ter-butilaminopropanos sustituidos. |
ES368399A ES368399A1 (es) | 1967-06-15 | 1969-06-16 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-ter-butilamino propanos sustituidos. |
ES69368396A ES368396A1 (es) | 1967-06-15 | 1969-06-16 | Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3-ter-butilaminopropanos sustituidos. |
GB3825170A GB1318533A (en) | 1967-06-15 | 1970-08-07 | 3-2-cyanophenoxy-2-hydroxy-n-ethyl-propylamine |
NL7111854.A NL158171B (nl) | 1967-06-15 | 1971-08-27 | Werkwijze voor het op op zichzelf bekende wijze bereiden van een 1-(2- propargyloxyfenoxy) 3-alkylamino 2-propanol, werkwijze voor het bereiden van preparaten die deze verbinding bevatten, alsmede de verkregen gevormde preparaten. |
US408743A US3868460A (en) | 1967-02-06 | 1973-10-23 | Therapeutic compositions and method |
MY1973288A MY7300288A (en) | 1967-06-15 | 1973-12-31 | Propanolamine derivatives |
YU2289/74A YU33776B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
YU2288/74A YU33775B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
YU2291/74A YU33778B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
YU2292/74A YU33779B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
YU2293/74A YU35578B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert. butyl amino propanes |
YU2294/74A YU33780B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
YU2290/74A YU33777B (en) | 1967-06-15 | 1974-08-21 | Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes |
US05/502,634 US3940489A (en) | 1967-02-06 | 1974-09-03 | Therapeutic compositions and method |
JP49119881A JPS5112613B1 (sv) | 1967-06-15 | 1974-10-17 | |
US05/564,308 US3961071A (en) | 1967-02-06 | 1975-04-02 | Therapeutic compositions and method |
US05/571,790 US4039685A (en) | 1967-02-06 | 1975-04-25 | 1-phenoxy-2-hydroxy-3-tert.-butylamino propane antiarrhythmic compounds |
US05/656,000 US4036988A (en) | 1967-02-06 | 1976-02-06 | Therapeutic compositions and method |
IT7949447A IT7949447A0 (it) | 1967-02-06 | 1979-06-18 | 1-cianofenossi-2-idrossi-3-terz.butilamminopropani loro sali eprocedimento di preparazione |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1967B0093025 DE1593782B2 (de) | 1967-06-15 | 1967-06-15 | 1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
Publications (2)
Publication Number | Publication Date |
---|---|
DE1593782A1 DE1593782A1 (de) | 1972-04-20 |
DE1593782B2 true DE1593782B2 (de) | 1976-09-09 |
Family
ID=6986720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1967B0093025 Granted DE1593782B2 (de) | 1967-02-06 | 1967-06-15 | 1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
Country Status (17)
Country | Link |
---|---|
JP (2) | JPS51100B1 (sv) |
AT (8) | AT289077B (sv) |
BE (1) | BE716647A (sv) |
BG (6) | BG15039A3 (sv) |
CH (1) | CH495950A (sv) |
DE (1) | DE1593782B2 (sv) |
DK (1) | DK127059B (sv) |
ES (6) | ES354823A1 (sv) |
FI (1) | FI48922C (sv) |
FR (2) | FR1583559A (sv) |
GB (1) | GB1187546A (sv) |
IE (1) | IE32373B1 (sv) |
IL (1) | IL30181A (sv) |
MY (1) | MY7300288A (sv) |
NL (2) | NL6808196A (sv) |
SE (1) | SE355571B (sv) |
YU (7) | YU33780B (sv) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3937834A (en) | 1970-10-02 | 1976-02-10 | Ciba-Geigy Corporation | Pharmaceutical preparations |
JPS57125772U (sv) * | 1981-01-30 | 1982-08-05 | ||
DE3744371A1 (de) * | 1987-12-29 | 1989-07-13 | Jacobs Suchard Ag | Verpackung fuer suesswaren |
DE4014252A1 (de) * | 1990-05-04 | 1991-11-07 | Boehringer Ingelheim Vetmed | Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL301580A (sv) * | 1962-12-11 |
-
0
- NL NL136601D patent/NL136601C/xx active
-
1967
- 1967-06-15 DE DE1967B0093025 patent/DE1593782B2/de active Granted
- 1967-06-17 FR FR1583559D patent/FR1583559A/fr not_active Expired
-
1968
- 1968-06-05 JP JP43038048A patent/JPS51100B1/ja active Pending
- 1968-06-08 ES ES354823A patent/ES354823A1/es not_active Expired
- 1968-06-11 NL NL6808196A patent/NL6808196A/xx unknown
- 1968-06-13 SE SE07980/68A patent/SE355571B/xx unknown
- 1968-06-13 CH CH876668A patent/CH495950A/de not_active IP Right Cessation
- 1968-06-14 DK DK281968AA patent/DK127059B/da not_active IP Right Cessation
- 1968-06-14 GB GB28529/68A patent/GB1187546A/en not_active Expired
- 1968-06-14 AT AT247870A patent/AT289077B/de active
- 1968-06-14 IL IL6830181A patent/IL30181A/xx unknown
- 1968-06-14 AT AT572568A patent/AT289067B/de not_active IP Right Cessation
- 1968-06-14 AT AT248270A patent/AT289081B/de active
- 1968-06-14 FI FI681664A patent/FI48922C/sv active
- 1968-06-14 AT AT248370A patent/AT289082B/de not_active IP Right Cessation
- 1968-06-14 AT AT248170A patent/AT289080B/de active
- 1968-06-14 IE IE710/68A patent/IE32373B1/xx unknown
- 1968-06-14 AT AT248070A patent/AT289079B/de active
- 1968-06-14 AT AT247770A patent/AT289076B/de not_active IP Right Cessation
- 1968-06-14 AT AT247970A patent/AT289078B/de not_active IP Right Cessation
- 1968-06-14 BE BE716647D patent/BE716647A/xx not_active IP Right Cessation
- 1968-06-15 BG BG011629A patent/BG15039A3/bg unknown
- 1968-06-15 BG BG011627A patent/BG15037A3/bg unknown
- 1968-06-15 BG BG011628A patent/BG15038A3/bg unknown
- 1968-06-15 BG BG011632A patent/BG15042A3/bg unknown
- 1968-06-15 BG BG011631A patent/BG15041A3/bg unknown
- 1968-06-15 BG BG011630A patent/BG15040A3/bg unknown
- 1968-09-17 FR FR166464A patent/FR8162M/fr not_active Expired
-
1969
- 1969-06-16 ES ES69368396A patent/ES368396A1/es not_active Expired
- 1969-06-16 ES ES368398A patent/ES368398A1/es not_active Expired
- 1969-06-16 ES ES368401A patent/ES368401A1/es not_active Expired
- 1969-06-16 ES ES368399A patent/ES368399A1/es not_active Expired
- 1969-06-16 ES ES368395A patent/ES368395A1/es not_active Expired
-
1973
- 1973-12-31 MY MY1973288A patent/MY7300288A/xx unknown
-
1974
- 1974-08-21 YU YU2294/74A patent/YU33780B/xx unknown
- 1974-08-21 YU YU2288/74A patent/YU33775B/xx unknown
- 1974-08-21 YU YU2293/74A patent/YU35578B/xx unknown
- 1974-08-21 YU YU2290/74A patent/YU33777B/xx unknown
- 1974-08-21 YU YU2292/74A patent/YU33779B/xx unknown
- 1974-08-21 YU YU2289/74A patent/YU33776B/xx unknown
- 1974-08-21 YU YU2291/74A patent/YU33778B/xx unknown
- 1974-10-17 JP JP49119881A patent/JPS5112613B1/ja active Pending
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