DE1445505B2 - Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2) - Google Patents

Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2)

Info

Publication number
DE1445505B2
DE1445505B2 DE1963B0073766 DEB0073766A DE1445505B2 DE 1445505 B2 DE1445505 B2 DE 1445505B2 DE 1963B0073766 DE1963B0073766 DE 1963B0073766 DE B0073766 A DEB0073766 A DE B0073766A DE 1445505 B2 DE1445505 B2 DE 1445505B2
Authority
DE
Germany
Prior art keywords
dichloro
methylphenyl
diazacyclopentene
amino
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1963B0073766
Other languages
German (de)
English (en)
Other versions
DE1445505A1 (de
Inventor
Helmut Dr.; Hauptmann Karl Heinz Dr.; Zeile Karl Dr.; 6507 Ingelheim Stähle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL123037D priority Critical patent/NL123037C/xx
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Priority to DE1963B0073766 priority patent/DE1445505B2/de
Priority to US327806A priority patent/US3236857A/en
Priority to DE19641445538 priority patent/DE1445538A1/de
Priority to CH1189367A priority patent/CH451172A/de
Priority to CH1193264A priority patent/CH437316A/de
Priority to CH1193164A priority patent/CH451169A/de
Priority to SE1071068A priority patent/SE353721B/xx
Priority to SE1110764A priority patent/SE313310B/xx
Priority to FI201764A priority patent/FI44913C/fi
Priority to GB39420/64A priority patent/GB1034938A/en
Priority to FR990056A priority patent/FR3968M/fr
Priority to FR990057A priority patent/FR1448765A/fr
Priority to DK486964A priority patent/DK108364C/da
Priority to BE653933D priority patent/BE653933A/xx
Priority to BR16314264A priority patent/BR6463142D0/pt
Priority to NL6411516A priority patent/NL6411516A/xx
Priority to IL2218664A priority patent/IL22186A/xx
Priority to DK482765A priority patent/DK117000B/da
Priority to US515479A priority patent/US3454701A/en
Publication of DE1445505A1 publication Critical patent/DE1445505A1/de
Priority to FI260071A priority patent/FI49614C/fi
Publication of DE1445505B2 publication Critical patent/DE1445505B2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE1963B0073766 1961-10-09 1963-10-04 Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2) Granted DE1445505B2 (de)

Priority Applications (21)

Application Number Priority Date Filing Date Title
NL123037D NL123037C (fr) 1963-10-04
DE1963B0073766 DE1445505B2 (de) 1963-10-04 1963-10-04 Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2)
US327806A US3236857A (en) 1961-10-09 1963-12-03 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE19641445538 DE1445538A1 (de) 1963-10-04 1964-07-31 Verfahren zur Herstellung neuer substituierter Phenylamino-1,3-diazacyclopentene-(2)
CH1189367A CH451172A (de) 1963-10-04 1964-09-14 Verfahren zur Herstellung neuer substituierter Phenylamino-1,3-diazacyclopentene-(2)
CH1193264A CH437316A (de) 1963-10-04 1964-09-14 Verfahren zur Herstellung von substituierten Phenyl-amino-1,3-diazacyclopenten-(2)-Verbindungen
CH1193164A CH451169A (de) 1963-10-04 1964-09-14 Verfahren zur Herstellung neuer substituierter Phenylamino-1,3-diazacyclopentene-(2)
SE1071068A SE353721B (fr) 1963-10-04 1964-09-16
SE1110764A SE313310B (fr) 1963-10-04 1964-09-16
FI201764A FI44913C (fi) 1963-10-04 1964-09-23 Menetelmä uusien substituoitujen fenyyliamino-1,3-diatsasyklopenteenien-(2) valmistamiseksi, joilla on verenpainetta alentava ja rauhoittava vaikutus
GB39420/64A GB1034938A (en) 1963-10-04 1964-09-28 2-phenylamino-1,3-diazacyclopent-2-enes
FR990056A FR3968M (fr) 1963-10-04 1964-10-01
FR990057A FR1448765A (fr) 1963-10-04 1964-10-01 Procédé pour fabriquer des nouveaux phénylamino-1, 3-diazacyclopentènes-(2)-substitués
DK486964A DK108364C (da) 1963-10-04 1964-10-02 Fremgangsmåde til fremstilling af substituerede phenylamino-1,3-diazacyclopentener-(2)-, eller syreadditionssalte heraf.
BE653933D BE653933A (fr) 1963-10-04 1964-10-02
BR16314264A BR6463142D0 (pt) 1963-10-04 1964-10-02 Processo para a obtencao de novos fenilamino-1,3- diazacicativo
NL6411516A NL6411516A (fr) 1961-10-09 1964-10-02
IL2218664A IL22186A (en) 1963-10-04 1964-10-04 Phenylamino-1,3-diazacyclopentenes,process for their preparation and compositions containing them
DK482765A DK117000B (da) 1963-10-04 1965-09-20 Fremgangsmåde til fremstilling af substituerede phenylamino-1,3-diazacyclopentener-(2) eller syreadditionssalte heraf.
US515479A US3454701A (en) 1961-10-09 1965-12-21 2 - (phenyl - amino) - 1,3 - diazacyclopentene - (2) substitution products for reducing blood pressure
FI260071A FI49614C (fi) 1963-10-04 1971-09-17 Menetelmä substituoitujen fenyyliamino-1,3-diatsasyklopenteenien-(2) v almistamiseksi, joilla on verisuonia supistava, verenpainetta alentava ja rauhoittava vaikutus.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1963B0073766 DE1445505B2 (de) 1963-10-04 1963-10-04 Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2)
DEB0077922 1964-07-31
DEB0077921 1964-07-31

Publications (2)

Publication Number Publication Date
DE1445505A1 DE1445505A1 (de) 1969-10-02
DE1445505B2 true DE1445505B2 (de) 1976-12-16

Family

ID=27209240

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1963B0073766 Granted DE1445505B2 (de) 1961-10-09 1963-10-04 Im phenylkern substituierte 2-phenylamino-1,3-diazacyclopentene-(2)
DE19641445538 Pending DE1445538A1 (de) 1963-10-04 1964-07-31 Verfahren zur Herstellung neuer substituierter Phenylamino-1,3-diazacyclopentene-(2)

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19641445538 Pending DE1445538A1 (de) 1963-10-04 1964-07-31 Verfahren zur Herstellung neuer substituierter Phenylamino-1,3-diazacyclopentene-(2)

Country Status (11)

Country Link
BE (1) BE653933A (fr)
BR (1) BR6463142D0 (fr)
CH (3) CH437316A (fr)
DE (2) DE1445505B2 (fr)
DK (2) DK108364C (fr)
FI (2) FI44913C (fr)
FR (2) FR1448765A (fr)
GB (1) GB1034938A (fr)
IL (1) IL22186A (fr)
NL (1) NL123037C (fr)
SE (2) SE313310B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545628A1 (de) * 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2)
BE754832A (fr) * 1969-08-14 1971-02-15 Beecham Group Ltd Iminazolines
US4125620A (en) 1974-10-01 1978-11-14 Boehringer Ingelheim Gmbh 2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof
MTP837B (en) 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
DE2854659A1 (de) * 1978-12-18 1980-07-10 Boehringer Sohn Ingelheim Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
CA1175434A (fr) 1980-09-10 1984-10-02 Hoffmann-La Roche Limited Derives de ¬(2-phenylamino-1-imidazolidinyloxy) methyl|pyridine 1-oxyde
US4444782A (en) * 1982-12-23 1984-04-24 Smithkline Beckman Corporation 2(4-tert.-Butyl-2,6-dichlorophenyl-imino)imidazolidine and use as an anti-hypertension agent

Also Published As

Publication number Publication date
FR1448765A (fr) 1966-03-18
IL22186A (en) 1968-06-20
NL123037C (fr)
SE353721B (fr) 1973-02-12
DK117000B (da) 1970-03-09
FI49614B (fr) 1975-04-30
FI44913B (fr) 1971-11-01
FI49614C (fi) 1975-08-11
BR6463142D0 (pt) 1973-07-19
GB1034938A (en) 1966-07-06
SE313310B (fr) 1969-08-11
DK108364C (da) 1967-11-27
BE653933A (fr) 1965-04-02
CH451169A (de) 1968-05-15
DE1445505A1 (de) 1969-10-02
CH437316A (de) 1967-06-15
FR3968M (fr) 1966-02-28
CH451172A (de) 1968-05-15
DE1445538A1 (de) 1969-02-20
FI44913C (fi) 1972-02-10

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Legal Events

Date Code Title Description
SH Request for examination between 03.10.1968 and 22.04.1971
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977