DE1418957A1 - Steroide der Pregnanreihe und Verfahren zu ihrer Herstellung - Google Patents

Steroide der Pregnanreihe und Verfahren zu ihrer Herstellung

Info

Publication number
DE1418957A1
DE1418957A1 DE19601418957 DE1418957A DE1418957A1 DE 1418957 A1 DE1418957 A1 DE 1418957A1 DE 19601418957 DE19601418957 DE 19601418957 DE 1418957 A DE1418957 A DE 1418957A DE 1418957 A1 DE1418957 A1 DE 1418957A1
Authority
DE
Germany
Prior art keywords
acetate
dione
solution
dihydroxy
ecm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19601418957
Other languages
German (de)
English (en)
Inventor
Hoffsommer Jun Robert Dubios
Wendler Norman Lord
David Taub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1418957A1 publication Critical patent/DE1418957A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Arrangement And Mounting Of Devices That Control Transmission Of Motive Force (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19601418957 1959-03-24 1960-03-17 Steroide der Pregnanreihe und Verfahren zu ihrer Herstellung Pending DE1418957A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80142959 US3136760A (en) 1959-03-24 1959-03-24 16-alkylene pregnene derivatives

Publications (1)

Publication Number Publication Date
DE1418957A1 true DE1418957A1 (de) 1969-03-27

Family

ID=25181065

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19601418957 Pending DE1418957A1 (de) 1959-03-24 1960-03-17 Steroide der Pregnanreihe und Verfahren zu ihrer Herstellung
DEM52478A Pending DE1196653B (de) 1959-03-24 1960-03-17 Verfahren zur Herstellung von 16-Alkyliden-steroidverbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DEM52478A Pending DE1196653B (de) 1959-03-24 1960-03-17 Verfahren zur Herstellung von 16-Alkyliden-steroidverbindungen

Country Status (10)

Country Link
US (1) US3136760A (enExample)
AT (1) AT249880B (enExample)
BE (1) BE588587A (enExample)
CH (2) CH409951A (enExample)
DE (2) DE1418957A1 (enExample)
DK (2) DK105867C (enExample)
FR (1) FR1466203A (enExample)
GB (1) GB946860A (enExample)
NO (1) NO122647B (enExample)
SE (1) SE314980B (enExample)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2666016A (en) * 1951-01-25 1954-01-12 Searle & Co Biochemical processes for the oxygenation of steroids
US2756179A (en) * 1953-04-20 1956-07-24 Olin Mathieson Production of delta 1 bonds in the a ring of the cyclopentanopolyhydrophenanthrene nucleus by streptomyces lavendulae
US2863862A (en) * 1954-12-10 1958-12-09 Syntex Sa 1-methyl steroid derivatives and method for the production thereof
US2932639A (en) * 1955-02-02 1960-04-12 Schering Corp Delta1, 4-16, 17-oxido-pregnadienes
US2867633A (en) * 1956-11-23 1959-01-06 Upjohn Co 11-oxygenated-6-methyl-17alpha-hydroxy-4-pregnene-3, 20-diones
US2942012A (en) * 1956-11-28 1960-06-21 Merck & Co Inc 16-keto steroids of the pregnane series and methods for making same
US2966504A (en) * 1957-02-05 1960-12-27 Merck & Co Inc Methods of producing 16-oxy steroids
US2932656A (en) * 1957-06-19 1960-04-12 Merck & Co Inc Production of delta1, 4-3, 20-diketopregnadienes from the corresponding semicarbazones
US2867630A (en) * 1958-06-09 1959-01-06 Upjohn Co 6-fluoro androstenes
US2865808A (en) * 1958-06-09 1958-12-23 Pfizer & Co C 16-methylene pregnene derivatives
US2954386A (en) * 1958-08-22 1960-09-27 Merck & Co Inc 16-methyl-17-lower acyloxy-21-fluorosteroid-3, 2-diones
US2944070A (en) * 1958-09-08 1960-07-05 Merck & Co Inc Preparation of 16alpha-lower alkyl steroids

Also Published As

Publication number Publication date
DK118875B (da) 1970-10-19
US3136760A (en) 1964-06-09
DK105867C (da) 1966-11-21
GB946860A (en) 1964-01-15
CH409951A (de) 1966-03-31
AT249880B (de) 1966-10-10
SE314980B (enExample) 1969-09-22
BE588587A (fr) 1960-09-14
FR1466203A (fr) 1967-01-20
CH410939A (fr) 1966-04-15
DE1196653B (de) 1965-07-15
NO122647B (enExample) 1971-07-26

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Legal Events

Date Code Title Description
SH Request for examination between 03.10.1968 and 22.04.1971