DK118875B - Fremgangsmåde til fremstilling af 17α-hydroxy-16-alkylen-steroider. - Google Patents

Fremgangsmåde til fremstilling af 17α-hydroxy-16-alkylen-steroider.

Info

Publication number
DK118875B
DK118875B DK37361A DK37361A DK118875B DK 118875 B DK118875 B DK 118875B DK 37361 A DK37361 A DK 37361A DK 37361 A DK37361 A DK 37361A DK 118875 B DK118875 B DK 118875B
Authority
DK
Denmark
Prior art keywords
steroids
alkylene
hydroxy
preparation
alkylene steroids
Prior art date
Application number
DK37361A
Other languages
English (en)
Inventor
N Wendler
R Hoffsommer
D Taub
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK118875B publication Critical patent/DK118875B/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Arrangement And Mounting Of Devices That Control Transmission Of Motive Force (AREA)
DK37361A 1959-03-24 1961-01-27 Fremgangsmåde til fremstilling af 17α-hydroxy-16-alkylen-steroider. DK118875B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80142959 US3136760A (en) 1959-03-24 1959-03-24 16-alkylene pregnene derivatives

Publications (1)

Publication Number Publication Date
DK118875B true DK118875B (da) 1970-10-19

Family

ID=25181065

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96360A DK105867C (da) 1959-03-24 1960-03-12 Fremgangsmåde til fremstilling af 16-methylen-11,17-dihydroxy-21-acyloxy-3,20-dioxo-1,4-pregnadiener.
DK37361A DK118875B (da) 1959-03-24 1961-01-27 Fremgangsmåde til fremstilling af 17α-hydroxy-16-alkylen-steroider.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96360A DK105867C (da) 1959-03-24 1960-03-12 Fremgangsmåde til fremstilling af 16-methylen-11,17-dihydroxy-21-acyloxy-3,20-dioxo-1,4-pregnadiener.

Country Status (10)

Country Link
US (1) US3136760A (da)
AT (1) AT249880B (da)
BE (1) BE588587A (da)
CH (2) CH410939A (da)
DE (2) DE1196653B (da)
DK (2) DK105867C (da)
FR (1) FR1466203A (da)
GB (1) GB946860A (da)
NO (1) NO122647B (da)
SE (1) SE314980B (da)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2666016A (en) * 1951-01-25 1954-01-12 Searle & Co Biochemical processes for the oxygenation of steroids
US2756179A (en) * 1953-04-20 1956-07-24 Olin Mathieson Production of delta 1 bonds in the a ring of the cyclopentanopolyhydrophenanthrene nucleus by streptomyces lavendulae
US2863862A (en) * 1954-12-10 1958-12-09 Syntex Sa 1-methyl steroid derivatives and method for the production thereof
US2932639A (en) * 1955-02-02 1960-04-12 Schering Corp Delta1, 4-16, 17-oxido-pregnadienes
US2867633A (en) * 1956-11-23 1959-01-06 Upjohn Co 11-oxygenated-6-methyl-17alpha-hydroxy-4-pregnene-3, 20-diones
US2942012A (en) * 1956-11-28 1960-06-21 Merck & Co Inc 16-keto steroids of the pregnane series and methods for making same
US2966504A (en) * 1957-02-05 1960-12-27 Merck & Co Inc Methods of producing 16-oxy steroids
US2932656A (en) * 1957-06-19 1960-04-12 Merck & Co Inc Production of delta1, 4-3, 20-diketopregnadienes from the corresponding semicarbazones
US2867630A (en) * 1958-06-09 1959-01-06 Upjohn Co 6-fluoro androstenes
US2865808A (en) * 1958-06-09 1958-12-23 Pfizer & Co C 16-methylene pregnene derivatives
US2954386A (en) * 1958-08-22 1960-09-27 Merck & Co Inc 16-methyl-17-lower acyloxy-21-fluorosteroid-3, 2-diones
US2944070A (en) * 1958-09-08 1960-07-05 Merck & Co Inc Preparation of 16alpha-lower alkyl steroids

Also Published As

Publication number Publication date
DK105867C (da) 1966-11-21
AT249880B (de) 1966-10-10
DE1196653B (de) 1965-07-15
BE588587A (fr) 1960-09-14
SE314980B (da) 1969-09-22
NO122647B (da) 1971-07-26
CH410939A (fr) 1966-04-15
FR1466203A (fr) 1967-01-20
US3136760A (en) 1964-06-09
GB946860A (en) 1964-01-15
CH409951A (de) 1966-03-31
DE1418957A1 (de) 1969-03-27

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