DE122005000029I2 - Synergistische kombinationen von Zidovudine, 1592u89 und 3TC - Google Patents

Synergistische kombinationen von Zidovudine, 1592u89 und 3TC

Info

Publication number
DE122005000029I2
DE122005000029I2 DE1996622386 DE69622386C DE122005000029I2 DE 122005000029 I2 DE122005000029 I2 DE 122005000029I2 DE 1996622386 DE1996622386 DE 1996622386 DE 69622386 C DE69622386 C DE 69622386C DE 122005000029 I2 DE122005000029 I2 DE 122005000029I2
Authority
DE
Germany
Prior art keywords
zidovudine
synergistic combinations
synergistic
combinations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE1996622386
Other languages
German (de)
English (en)
Other versions
DE69622386D1 (de
DE69622386T2 (de
Inventor
Walter Barry
Clair Heider St
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122005000029(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9506490.3A external-priority patent/GB9506490D0/en
Priority claimed from GBGB9506489.5A external-priority patent/GB9506489D0/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE122005000029I2 publication Critical patent/DE122005000029I2/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
DE1996622386 1995-03-30 1996-03-28 Synergistische kombinationen von Zidovudine, 1592u89 und 3TC Active DE122005000029I2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506490.3A GB9506490D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GBGB9506489.5A GB9506489D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
PCT/EP1996/001352 WO1996030025A1 (en) 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592u89 and 3tc or ftc

Publications (1)

Publication Number Publication Date
DE122005000029I2 true DE122005000029I2 (de) 2006-04-27

Family

ID=26306774

Family Applications (3)

Application Number Title Priority Date Filing Date
DE200512000029 Pending DE122005000029I1 (de) 1995-03-30 1996-03-28 Synergistische Kombinationen von Zidovudine, 1592u89 und 3tc.
DE1996622386 Active DE122005000029I2 (de) 1995-03-30 1996-03-28 Synergistische kombinationen von Zidovudine, 1592u89 und 3TC
DE69622386T Expired - Lifetime DE69622386T2 (de) 1995-03-30 1996-03-28 Synergistische kombinationen von zidovudine, 1592u89 und 3tc

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200512000029 Pending DE122005000029I1 (de) 1995-03-30 1996-03-28 Synergistische Kombinationen von Zidovudine, 1592u89 und 3tc.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69622386T Expired - Lifetime DE69622386T2 (de) 1995-03-30 1996-03-28 Synergistische kombinationen von zidovudine, 1592u89 und 3tc

Country Status (35)

Country Link
US (1) US6417191B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0817637B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2954357B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100542536B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1103593C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AP (1) AP652A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE220551T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU715213B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (3) BRPI9607851B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2216634C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ295940B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (3) DE122005000029I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0817637T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EA (1) EA000626B3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EE (1) EE04047B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2179193T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR05C0022I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GE (1) GEP20022647B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU224010B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL117727A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU91171I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9707316A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY115461A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL300195I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (2) NO313787B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ306419A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA10616A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL187085B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT817637E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO117995B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI0817637T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK283825B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR199701074T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA60293C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1996030025A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JP2000515852A (ja) * 1996-06-25 2000-11-28 グラクソ、グループ、リミテッド Hivの治療に使用するためのvx478、ジドブジン、ftcおよび/または3tcを含んでなる組合わせ
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
TW536403B (en) * 1997-03-24 2003-06-11 Glaxo Group Ltd An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy
AU769660B2 (en) * 1997-05-17 2004-01-29 Glaxo Group Limited Carbocyclic nucleoside hemisulfate and its use in treating viral infections
WO1998052570A1 (en) * 1997-05-17 1998-11-26 Glaxo Group Limited Antiviral combinations containing the carbocyclic nucleoside 1592u89
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
WO1999060988A2 (en) * 1998-05-29 1999-12-02 University Of Florida Combination therapy for treatment of fiv infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
AP2220A (en) * 2001-05-11 2011-03-24 Cipla Medpro Pty Ltd Pharmaceutical composition.
TW200403061A (en) * 2002-06-04 2004-03-01 Glaxo Group Ltd Pharmaceutical compositions
KR20080032014A (ko) 2003-01-14 2008-04-11 길리애드 사이언시즈, 인코포레이티드 복합 항바이러스 치료를 위한 조성물 및 방법
KR20050119652A (ko) 2003-03-24 2005-12-21 에프. 호프만-라 로슈 아게 역전사 효소 저해제로서의 벤질-피리다진온
RU2006117793A (ru) 2003-10-24 2007-12-10 Иммунэйд Пти Лтд. (Au) Способ лечения
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CA2625047A1 (en) 2005-10-19 2007-04-26 F. Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
WO2008071587A2 (en) 2006-12-13 2008-06-19 F. Hoffmann-La Roche Ag 2-(piperidin-4-yl)-4-phenoxy- or phenylamino-pyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors
JP5467870B2 (ja) * 2007-02-09 2014-04-09 アルファファーム ピーティーワイ リミテッド 異なる物理的形態の2種以上の有効医薬成分を含有する投薬形態
WO2010135781A1 (en) 2009-05-27 2010-12-02 Immunaid Pty Ltd Methods of treating diseases
PT3494972T (pt) 2010-01-27 2024-02-12 Viiv Healthcare Co Combinações de dolutegravir e lamivudina para o tratamento de infeção pelo hiv
HK1220390A1 (zh) 2013-08-29 2017-05-05 Teva Pharmaceutical Industries Ltd. 包括恩曲他滨,替诺福韦,达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂
AU2015245217A1 (en) 2014-04-08 2016-10-13 Teva Pharmaceutical Industries Ltd. Unit dosage form comprising Emtricitabine, Tenofovir, Darunavir and Ritonavir
CN117164657A (zh) 2014-08-12 2023-12-05 莫纳什大学 定向淋巴的前药
CA2997106C (en) 2015-09-08 2024-06-04 Monash University Lymph directing prodrugs
EP3675838A4 (en) 2017-08-29 2021-04-21 PureTech LYT, Inc. Lymphatic system-directing lipid prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
CN115348864A (zh) 2020-02-05 2022-11-15 纯技术Lyt股份有限公司 神经甾体的脂质前药

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US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5122517A (en) 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
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GB9104740D0 (en) 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
ES2083668T5 (es) * 1991-05-16 2001-06-16 Glaxo Group Ltd Combinaciones antiviricas que contienen analogos de nucleosido.
EP0639971B1 (en) * 1992-05-13 1999-09-22 The Wellcome Foundation Limited Therapeutic combinations
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt
US5869461A (en) 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
WO1997049410A1 (en) 1996-06-25 1997-12-31 Glaxo Group Limited Combinations comprising vx478, zidovudine and/or 1592u89 for use in the treatment of hiv
JP2000515852A (ja) 1996-06-25 2000-11-28 グラクソ、グループ、リミテッド Hivの治療に使用するためのvx478、ジドブジン、ftcおよび/または3tcを含んでなる組合わせ
DE10226522A1 (de) 2002-06-14 2003-12-24 Degussa Verwendung von Übergangsmetallkomplexen mit stickstoffhaltigen mehrzähnigen Liganden als Bleichkatalysator und Bleichmittelzusammensetzung

Also Published As

Publication number Publication date
CN1185110A (zh) 1998-06-17
BR9607851A (pt) 1998-07-21
AP652A (en) 1998-06-19
AP9701089A0 (en) 1997-10-31
KR100542536B1 (ko) 2006-03-23
NO313787B1 (no) 2002-12-02
EA000626B3 (ru) 2016-04-29
SI0817637T1 (en) 2002-10-31
CA2216634C (en) 2004-07-20
DK0817637T3 (da) 2002-11-11
MX9707316A (es) 1997-11-29
IL117727A0 (en) 1996-07-23
CN1103593C (zh) 2003-03-26
RO117995B1 (ro) 2002-12-30
EP0817637B1 (en) 2002-07-17
DE69622386D1 (de) 2002-08-22
EA199700203A1 (ru) 1998-02-26
EE04047B1 (et) 2003-06-16
BRPI9607851B8 (pt) 2019-11-05
FR05C0022I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2005-06-10
HU224010B1 (hu) 2005-04-28
LU91171I2 (fr) 2005-07-04
BRPI9612992B1 (pt) 2020-08-04
NO974510D0 (no) 1997-09-29
JPH10511682A (ja) 1998-11-10
KR19980703420A (ko) 1998-11-05
WO1996030025A1 (en) 1996-10-03
AU715213B2 (en) 2000-01-20
NZ306419A (en) 2000-01-28
PT817637E (pt) 2002-11-29
BR9607851B1 (pt) 2009-01-13
FR05C0022I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2005-10-21
HUP9801571A3 (en) 2001-04-28
NL300195I2 (nl) 2005-11-01
JP2954357B2 (ja) 1999-09-27
EP0817637A1 (en) 1998-01-14
NL300195I1 (nl) 2005-08-01
NO2005014I2 (no) 2008-02-11
HK1009401A1 (en) 1999-09-10
PL322532A1 (en) 1998-02-02
EE9700240A (et) 1998-04-15
GEP20022647B (en) 2002-03-25
AU5497296A (en) 1996-10-16
CZ295940B6 (cs) 2005-12-14
OA10616A (en) 2001-03-15
US6417191B1 (en) 2002-07-09
UA60293C2 (uk) 2003-10-15
SK283825B6 (sk) 2004-02-03
DE122005000029I1 (de) 2005-10-06
HUP9801571A2 (hu) 1999-01-28
LU91171I9 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2018-12-28
NO974510L (no) 1997-09-29
ES2179193T3 (es) 2003-01-16
EA000626B1 (ru) 1999-12-29
DE69622386T2 (de) 2003-02-13
CZ309097A3 (cs) 1998-05-13
NO2005014I1 (no) 2005-06-06
MY115461A (en) 2003-06-30
IL117727A (en) 1999-11-30
CA2216634A1 (en) 1996-10-03
PL187085B1 (pl) 2004-05-31
ATE220551T1 (de) 2002-08-15
TR199701074T1 (xx) 1998-02-21
SK129597A3 (en) 1998-07-08

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