DE1103924B - Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica - Google Patents

Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica

Info

Publication number
DE1103924B
DE1103924B DEB54098A DEB0054098A DE1103924B DE 1103924 B DE1103924 B DE 1103924B DE B54098 A DEB54098 A DE B54098A DE B0054098 A DEB0054098 A DE B0054098A DE 1103924 B DE1103924 B DE 1103924B
Authority
DE
Germany
Prior art keywords
water
antihistamines
basic
salts
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEB54098A
Other languages
German (de)
English (en)
Inventor
Dr Peter Rieckmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DEB54098A priority Critical patent/DE1103924B/de
Priority to CH692360A priority patent/CH381685A/de
Priority to GB22820/60A priority patent/GB879901A/en
Priority to LU38913D priority patent/LU38913A1/xx
Priority to BE592585A priority patent/BE592585A/fr
Priority to FR832606A priority patent/FR1447118A/fr
Priority to FR840818A priority patent/FR977M/fr
Publication of DE1103924B publication Critical patent/DE1103924B/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00—Esters of sulfuric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00—Esters of sulfuric acids
    • C07C305/02—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C305/04—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated
    • C07C305/06—Hydrogenosulfates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DEB54098A 1959-07-21 1959-07-21 Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica Pending DE1103924B (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DEB54098A DE1103924B (de) 1959-07-21 1959-07-21 Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica
CH692360A CH381685A (de) 1959-07-21 1960-06-17 Verfahren zur Herstellung neuer wasserunlöslicher Salze von basischen Antihistaminica
GB22820/60A GB879901A (en) 1959-07-21 1960-06-29 New water-insoluble salts of basic antihistaminics
LU38913D LU38913A1 (US07655746-20100202-C00011.png) 1959-07-21 1960-07-04
BE592585A BE592585A (fr) 1959-07-21 1960-07-04 Nouveaux sels insolubles dans l'eau d'antihistaminiques basiques et leur préparation
FR832606A FR1447118A (fr) 1959-07-21 1960-07-11 Procédé de préparation d'alkylsulfates insoluble dans l'eau de composés aminés
FR840818A FR977M (US07655746-20100202-C00011.png) 1959-07-21 1960-10-11

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB54098A DE1103924B (de) 1959-07-21 1959-07-21 Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica

Publications (1)

Publication Number Publication Date
DE1103924B true DE1103924B (de) 1961-04-06

Family

ID=6970487

Family Applications (1)

Application Number Title Priority Date Filing Date
DEB54098A Pending DE1103924B (de) 1959-07-21 1959-07-21 Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica

Country Status (6)

Country Link
BE (1) BE592585A (US07655746-20100202-C00011.png)
CH (1) CH381685A (US07655746-20100202-C00011.png)
DE (1) DE1103924B (US07655746-20100202-C00011.png)
FR (1) FR977M (US07655746-20100202-C00011.png)
GB (1) GB879901A (US07655746-20100202-C00011.png)
LU (1) LU38913A1 (US07655746-20100202-C00011.png)

Also Published As

Publication number Publication date
CH381685A (de) 1964-09-15
GB879901A (en) 1961-10-11
FR977M (US07655746-20100202-C00011.png) 1961-12-04
LU38913A1 (US07655746-20100202-C00011.png) 1960-09-05
BE592585A (fr) 1960-10-31

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