DE10334309A1 - Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung - Google Patents
Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung Download PDFInfo
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- DE10334309A1 DE10334309A1 DE10334309A DE10334309A DE10334309A1 DE 10334309 A1 DE10334309 A1 DE 10334309A1 DE 10334309 A DE10334309 A DE 10334309A DE 10334309 A DE10334309 A DE 10334309A DE 10334309 A1 DE10334309 A1 DE 10334309A1
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- Prior art keywords
- alkyl
- alkylene
- aryl
- coo
- heterocycle
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (40)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334309A DE10334309A1 (de) | 2003-07-28 | 2003-07-28 | Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
| JO200481A JO2449B1 (en) | 2003-07-28 | 2004-06-14 | Thiosol derivatives - benziazothiazole dioxide, methods of preparation and use. |
| PE2004000664A PE20050326A1 (es) | 2003-07-28 | 2004-07-13 | Derivados de dioxido de tiazol-benzoisotiazol sustituidos como inhibidores de la actividad de la fosfatasa fosfotirosina 1b (ptp1b) |
| HK06112382.5A HK1091825B (en) | 2003-07-28 | 2004-07-15 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| AT04741034T ATE346065T1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol- benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
| JP2006521446A JP2007500145A (ja) | 2003-07-28 | 2004-07-15 | 置換チアゾール−ベンゾイソチアゾールジオキシド誘導体、それらの製造方法、およびそれらの使用 |
| KR1020067001721A KR20060052886A (ko) | 2003-07-28 | 2004-07-15 | 치환된 티아졸-벤조이소티아졸 디옥사이드 유도체, 이의제조 방법 및 이의 용도 |
| UAA200602134A UA83057C2 (ru) | 2003-07-28 | 2004-07-15 | Замещенные производные диоксида тиазолбензоизотиазола и их применение |
| DK04741034T DK1651644T3 (da) | 2003-07-28 | 2004-07-15 | Substituerede derivater af thiazol-benzoisothiazoldioxid, fremgangsmåde deraf og deres anvendelse |
| CA002533673A CA2533673A1 (en) | 2003-07-28 | 2004-07-15 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| SI200430126T SI1651644T1 (sl) | 2003-07-28 | 2004-07-15 | Substituirani tiazol-benzoizotiazol dioksidni derivati, postopek za njihovo pripravo in njihova uporaba |
| BRPI0412997-0A BRPI0412997A (pt) | 2003-07-28 | 2004-07-15 | derivados de dióxido de tiazol-benzoisotiazol substituìdos, método para produzir os mesmos e seu uso |
| PA20048607201A PA8607201A1 (es) | 2003-07-28 | 2004-07-15 | Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso |
| CNB2004800220877A CN100413862C (zh) | 2003-07-28 | 2004-07-15 | 取代的噻唑-苯并异噻唑二氧化物衍生物、其制备方法和其用途 |
| PT04741034T PT1651644E (pt) | 2003-07-28 | 2004-07-15 | Derivados substituídos de dióxido de tiazol-benzoisotiazole, processo para a sua preparação e sua utilização |
| DE502004002117T DE502004002117D1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
| PCT/EP2004/007847 WO2005012295A1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
| RU2006106231/04A RU2350613C2 (ru) | 2003-07-28 | 2004-07-15 | Замещенные производные диоксида тиазолбензоизотиазола, способ их получения и их применение |
| YUP-2006/0015A RS20060015A (sr) | 2003-07-28 | 2004-07-15 | Supstituisani derivati tiazol- benzoizotiazol dioksida, postupak za njihovu proizvodnju i njihovu primenu |
| NZ544975A NZ544975A (en) | 2003-07-28 | 2004-07-15 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| EP04741034A EP1651644B1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
| AU2004261370A AU2004261370B2 (en) | 2003-07-28 | 2004-07-15 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| OA1200600026A OA13198A (en) | 2003-07-28 | 2004-07-15 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and useof the same. |
| PL04741034T PL1651644T3 (pl) | 2003-07-28 | 2004-07-15 | Podstawione pochodne tiazolo-ditlenku benzoizotiazolu, sposób ich wytwarzania i zastosowanie |
| ES04741034T ES2276319T3 (es) | 2003-07-28 | 2004-07-15 | Derivados sustituidos de dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso. |
| GT200400146A GT200400146A (es) | 2003-07-28 | 2004-07-23 | Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso |
| ARP040102644A AR045113A1 (es) | 2003-07-28 | 2004-07-26 | Derivados sustituidos del dioxido de tiazolbenzoisotiazol, procedimiento para su preparacion y su uso |
| TW093122232A TW200524923A (en) | 2003-07-28 | 2004-07-26 | Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use |
| MYPI20043005A MY141197A (en) | 2003-07-28 | 2004-07-27 | Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use |
| US10/899,620 US7094794B2 (en) | 2003-07-28 | 2004-07-27 | Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use |
| UY28443A UY28443A1 (es) | 2003-07-28 | 2004-07-28 | Derivados sustituidos del dióxido de tiazol-benzoisotiazol, procedimiento para su preparación y su uso. |
| SA04250332A SA04250332B1 (ar) | 2003-07-28 | 2004-10-11 | مشتقات ثيوزايول-بنزوثيزول داي أوكسيد thiazole-benzoisothiazole dioxide بها استبدال,وعملية لتحضيرها واستخدامها |
| ZA200510378A ZA200510378B (en) | 2003-07-28 | 2005-12-21 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| CR8202A CR8202A (es) | 2003-07-28 | 2006-01-18 | Derivados sustituidos de dioxido de tiazol-beozoisotiazol, metodo para su produccion y uso de los mismos |
| IL173289A IL173289A0 (en) | 2003-07-28 | 2006-01-22 | Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same |
| MA28753A MA27932A1 (fr) | 2003-07-28 | 2006-01-26 | Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives |
| EC2006006326A ECSP066326A (es) | 2003-07-28 | 2006-01-26 | Derivados sustituidos del dióxido de tiazol-benzoisotiazol, método para su producción y uso de los mismos |
| TNP2006000030A TNSN06030A1 (en) | 2003-07-28 | 2006-01-27 | Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same |
| NO20060908A NO20060908L (no) | 2003-07-28 | 2006-02-24 | Substituerte tazol-benzoisotiazoldioksidderivater, deres fremstilling og anvendelse |
| CY20071100112T CY1105962T1 (el) | 2003-07-28 | 2007-01-29 | Υποκατεστημενα παραγωγα διοξειδιου θειαζολο-βενζοϊσοθειαζολιου, μεθοδος για την παραγωγη αυτων και η χρηση αυτων |
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|---|---|---|---|
| DE10334309A DE10334309A1 (de) | 2003-07-28 | 2003-07-28 | Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
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| DE10334309A1 true DE10334309A1 (de) | 2005-03-03 |
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| DE10334309A Withdrawn DE10334309A1 (de) | 2003-07-28 | 2003-07-28 | Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
| DE502004002117T Expired - Lifetime DE502004002117D1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
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| DE502004002117T Expired - Lifetime DE502004002117D1 (de) | 2003-07-28 | 2004-07-15 | Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung |
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Cited By (1)
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| DE102004026532A1 (de) * | 2004-05-29 | 2006-01-05 | Sanofi-Aventis Deutschland Gmbh | Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
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| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
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| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2025017207A1 (en) * | 2023-07-20 | 2025-01-23 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Inhibitors of smndc1 and their therapeutic use |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3539584A (en) * | 1967-11-14 | 1970-11-10 | Colgate Palmolive Co | 5-substituted-2,1-benzisothiazolines |
| JPH04128276A (ja) * | 1990-09-19 | 1992-04-28 | Pfizer Pharmaceut Co Ltd | アミノベンゾサルタム誘導体およびその用途 |
| HU224879B1 (en) * | 1995-06-02 | 2006-03-28 | Sanofi Aventis | Oxazolidinone derivatives, their preparation and pharmaceutical compositions containing these compounds |
| CO5190696A1 (es) * | 1999-06-16 | 2002-08-29 | Smithkline Beecham Corp | Antagonistas de los receptores il-8 |
| DE10038709A1 (de) * | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004026532A1 (de) * | 2004-05-29 | 2006-01-05 | Sanofi-Aventis Deutschland Gmbh | Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
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