UA83057C2 - Замещенные производные диоксида тиазолбензоизотиазола и их применение - Google Patents

Замещенные производные диоксида тиазолбензоизотиазола и их применение

Info

Publication number
UA83057C2
UA83057C2 UAA200602134A UAA200602134A UA83057C2 UA 83057 C2 UA83057 C2 UA 83057C2 UA A200602134 A UAA200602134 A UA A200602134A UA A200602134 A UAA200602134 A UA A200602134A UA 83057 C2 UA83057 C2 UA 83057C2
Authority
UA
Ukraine
Prior art keywords
same
substituted thiazole
dioxide derivatives
benzoisothiazole
benzoisothiazole dioxide
Prior art date
Application number
UAA200602134A
Other languages
English (en)
Ukrainian (uk)
Inventor
Штефан Петри
Карл-Хайнц Барингхаус
Норберт Теннагельс
Гюнтер Мюллер
Original Assignee
Санофи-Авентис Дойчланд Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофи-Авентис Дойчланд Гмбх filed Critical Санофи-Авентис Дойчланд Гмбх
Publication of UA83057C2 publication Critical patent/UA83057C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Данное изобретение касается соединений формулы (І)где остатки имеют указанные значения, а также их физиологически приемлемых солей. Указанные соединения пригодны, например, в качестве лекарственных средств для снижения сахара крови и для предупреждения и лечения диабета.
UAA200602134A 2003-07-28 2004-07-15 Замещенные производные диоксида тиазолбензоизотиазола и их применение UA83057C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10334309A DE10334309A1 (de) 2003-07-28 2003-07-28 Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
UA83057C2 true UA83057C2 (ru) 2008-06-10

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200602134A UA83057C2 (ru) 2003-07-28 2004-07-15 Замещенные производные диоксида тиазолбензоизотиазола и их применение

Country Status (38)

Country Link
EP (1) EP1651644B1 (ru)
JP (1) JP2007500145A (ru)
KR (1) KR20060052886A (ru)
CN (1) CN100413862C (ru)
AR (1) AR045113A1 (ru)
AT (1) ATE346065T1 (ru)
AU (1) AU2004261370B2 (ru)
BR (1) BRPI0412997A (ru)
CA (1) CA2533673A1 (ru)
CR (1) CR8202A (ru)
CY (1) CY1105962T1 (ru)
DE (2) DE10334309A1 (ru)
DK (1) DK1651644T3 (ru)
EC (1) ECSP066326A (ru)
ES (1) ES2276319T3 (ru)
GT (1) GT200400146A (ru)
HK (1) HK1091825A1 (ru)
IL (1) IL173289A0 (ru)
JO (1) JO2449B1 (ru)
MA (1) MA27932A1 (ru)
MY (1) MY141197A (ru)
NO (1) NO20060908L (ru)
NZ (1) NZ544975A (ru)
OA (1) OA13198A (ru)
PA (1) PA8607201A1 (ru)
PE (1) PE20050326A1 (ru)
PL (1) PL1651644T3 (ru)
PT (1) PT1651644E (ru)
RS (1) RS20060015A (ru)
RU (1) RU2350613C2 (ru)
SA (1) SA04250332B1 (ru)
SI (1) SI1651644T1 (ru)
TN (1) TNSN06030A1 (ru)
TW (1) TW200524923A (ru)
UA (1) UA83057C2 (ru)
UY (1) UY28443A1 (ru)
WO (1) WO2005012295A1 (ru)
ZA (1) ZA200510378B (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (de) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
ES2430115T3 (es) 2006-03-31 2013-11-19 Novartis Ag Inhibidor de DGAT
BRPI0715160A2 (pt) 2006-08-08 2013-06-11 Sanofi Aventis imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
UY31968A (es) 2008-07-09 2010-01-29 Sanofi Aventis Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
US8785608B2 (en) 2009-08-26 2014-07-22 Sanofi Crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
EP2683698B1 (de) 2011-03-08 2017-10-04 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120058A1 (de) 2011-03-08 2012-09-13 Sanofi Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8809324B2 (en) 2011-03-08 2014-08-19 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8895547B2 (en) 2011-03-08 2014-11-25 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
CO5190696A1 (es) * 1999-06-16 2002-08-29 Smithkline Beecham Corp Antagonistas de los receptores il-8
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
DE502004002117D1 (de) 2007-01-04
JP2007500145A (ja) 2007-01-11
PE20050326A1 (es) 2005-06-16
NZ544975A (en) 2010-02-26
ZA200510378B (en) 2006-11-29
SA04250332B1 (ar) 2008-02-25
EP1651644A1 (de) 2006-05-03
AR045113A1 (es) 2005-10-19
TW200524923A (en) 2005-08-01
CY1105962T1 (el) 2011-04-06
HK1091825A1 (en) 2007-01-26
CN1829715A (zh) 2006-09-06
AU2004261370B2 (en) 2009-07-16
RU2006106231A (ru) 2006-06-27
NO20060908L (no) 2006-02-24
PL1651644T3 (pl) 2007-03-30
SI1651644T1 (sl) 2007-02-28
CA2533673A1 (en) 2005-02-10
RS20060015A (en) 2007-12-31
RU2350613C2 (ru) 2009-03-27
PT1651644E (pt) 2007-01-31
WO2005012295A1 (de) 2005-02-10
IL173289A0 (en) 2006-06-11
KR20060052886A (ko) 2006-05-19
ES2276319T3 (es) 2007-06-16
UY28443A1 (es) 2005-02-28
DK1651644T3 (da) 2007-03-26
MY141197A (en) 2010-03-31
AU2004261370A1 (en) 2005-02-10
PA8607201A1 (es) 2005-03-03
DE10334309A1 (de) 2005-03-03
ECSP066326A (es) 2006-07-28
JO2449B1 (en) 2008-10-09
TNSN06030A1 (en) 2007-10-03
EP1651644B1 (de) 2006-11-22
BRPI0412997A (pt) 2006-10-03
CN100413862C (zh) 2008-08-27
MA27932A1 (fr) 2006-06-01
OA13198A (en) 2006-12-13
ATE346065T1 (de) 2006-12-15
GT200400146A (es) 2005-08-12
CR8202A (es) 2008-10-15

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