MA27932A1 - Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives - Google Patents

Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives

Info

Publication number
MA27932A1
MA27932A1 MA28753A MA28753A MA27932A1 MA 27932 A1 MA27932 A1 MA 27932A1 MA 28753 A MA28753 A MA 28753A MA 28753 A MA28753 A MA 28753A MA 27932 A1 MA27932 A1 MA 27932A1
Authority
MA
Morocco
Prior art keywords
derivatives
production
thiazole
dioxide
substituted benzoisothiazole
Prior art date
Application number
MA28753A
Other languages
English (en)
Inventor
Stefan Petry
Karl-Heinz Baringhaus
Norbert Tennagels
Guenter Mueller
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA27932A1 publication Critical patent/MA27932A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des composés de formule (I), dans laquelle les radicaux ont la signification indiquée dans la description, ainsi que leurs sels physiologiquement tolérables Ces composés sont appropriés par exemple comme médicaments servant à faire baisser le taux de sucre dans le sang et servant à la prévention et au traitement du diabète.
MA28753A 2003-07-28 2006-01-26 Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives MA27932A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10334309A DE10334309A1 (de) 2003-07-28 2003-07-28 Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
MA27932A1 true MA27932A1 (fr) 2006-06-01

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28753A MA27932A1 (fr) 2003-07-28 2006-01-26 Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives

Country Status (38)

Country Link
EP (1) EP1651644B1 (fr)
JP (1) JP2007500145A (fr)
KR (1) KR20060052886A (fr)
CN (1) CN100413862C (fr)
AR (1) AR045113A1 (fr)
AT (1) ATE346065T1 (fr)
AU (1) AU2004261370B2 (fr)
BR (1) BRPI0412997A (fr)
CA (1) CA2533673A1 (fr)
CR (1) CR8202A (fr)
CY (1) CY1105962T1 (fr)
DE (2) DE10334309A1 (fr)
DK (1) DK1651644T3 (fr)
EC (1) ECSP066326A (fr)
ES (1) ES2276319T3 (fr)
GT (1) GT200400146A (fr)
HK (1) HK1091825A1 (fr)
IL (1) IL173289A0 (fr)
JO (1) JO2449B1 (fr)
MA (1) MA27932A1 (fr)
MY (1) MY141197A (fr)
NO (1) NO20060908L (fr)
NZ (1) NZ544975A (fr)
OA (1) OA13198A (fr)
PA (1) PA8607201A1 (fr)
PE (1) PE20050326A1 (fr)
PL (1) PL1651644T3 (fr)
PT (1) PT1651644E (fr)
RS (1) RS20060015A (fr)
RU (1) RU2350613C2 (fr)
SA (1) SA04250332B1 (fr)
SI (1) SI1651644T1 (fr)
TN (1) TNSN06030A1 (fr)
TW (1) TW200524923A (fr)
UA (1) UA83057C2 (fr)
UY (1) UY28443A1 (fr)
WO (1) WO2005012295A1 (fr)
ZA (1) ZA200510378B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (de) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
ES2589736T3 (es) 2006-03-31 2016-11-16 Novartis Ag Derivados de piridina como inhibidores de DGAT
EP2061767B1 (fr) 2006-08-08 2014-12-17 Sanofi Imidazolidin-2,4-diones arylaminoaryl-alkyl-substituées, procédé de fabrication, médicaments les contenant et leur utilisation
EP2025674A1 (fr) 2007-08-15 2009-02-18 sanofi-aventis Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
TW201014822A (en) 2008-07-09 2010-04-16 Sanofi Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (fr) 2008-12-08 2010-06-17 Sanofi-Aventis Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant
DK2470552T3 (en) 2009-08-26 2014-02-17 Sanofi Sa NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2012120058A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120050A1 (fr) 2011-03-08 2012-09-13 Sanofi Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, médicaments contenant ces composés et leur utilisation
WO2012120057A1 (fr) 2011-03-08 2012-09-13 Sanofi Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation
WO2012120056A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120051A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation
WO2012120053A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
WO2012120055A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2567959B1 (fr) 2011-09-12 2014-04-16 Sanofi Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr) 2011-09-27 2015-10-21 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
CO5190696A1 (es) * 1999-06-16 2002-08-29 Smithkline Beecham Corp Antagonistas de los receptores il-8
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
AU2004261370B2 (en) 2009-07-16
RU2350613C2 (ru) 2009-03-27
CY1105962T1 (el) 2011-04-06
PT1651644E (pt) 2007-01-31
UY28443A1 (es) 2005-02-28
EP1651644A1 (fr) 2006-05-03
TW200524923A (en) 2005-08-01
EP1651644B1 (fr) 2006-11-22
ATE346065T1 (de) 2006-12-15
GT200400146A (es) 2005-08-12
DK1651644T3 (da) 2007-03-26
NO20060908L (no) 2006-02-24
CN1829715A (zh) 2006-09-06
CN100413862C (zh) 2008-08-27
SI1651644T1 (sl) 2007-02-28
RS20060015A (en) 2007-12-31
ES2276319T3 (es) 2007-06-16
WO2005012295A1 (fr) 2005-02-10
RU2006106231A (ru) 2006-06-27
KR20060052886A (ko) 2006-05-19
NZ544975A (en) 2010-02-26
JO2449B1 (en) 2008-10-09
DE10334309A1 (de) 2005-03-03
IL173289A0 (en) 2006-06-11
PL1651644T3 (pl) 2007-03-30
SA04250332B1 (ar) 2008-02-25
PE20050326A1 (es) 2005-06-16
AR045113A1 (es) 2005-10-19
DE502004002117D1 (de) 2007-01-04
CR8202A (es) 2008-10-15
MY141197A (en) 2010-03-31
ZA200510378B (en) 2006-11-29
UA83057C2 (ru) 2008-06-10
CA2533673A1 (fr) 2005-02-10
OA13198A (en) 2006-12-13
PA8607201A1 (es) 2005-03-03
JP2007500145A (ja) 2007-01-11
BRPI0412997A (pt) 2006-10-03
AU2004261370A1 (en) 2005-02-10
ECSP066326A (es) 2006-07-28
HK1091825A1 (en) 2007-01-26
TNSN06030A1 (en) 2007-10-03

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