UY28443A1 - Derivados sustituidos del dióxido de tiazol-benzoisotiazol, procedimiento para su preparación y su uso. - Google Patents

Derivados sustituidos del dióxido de tiazol-benzoisotiazol, procedimiento para su preparación y su uso.

Info

Publication number
UY28443A1
UY28443A1 UY28443A UY28443A UY28443A1 UY 28443 A1 UY28443 A1 UY 28443A1 UY 28443 A UY28443 A UY 28443A UY 28443 A UY28443 A UY 28443A UY 28443 A1 UY28443 A1 UY 28443A1
Authority
UY
Uruguay
Prior art keywords
benzoisotiazol
tiazol
dioxide
procedure
preparation
Prior art date
Application number
UY28443A
Other languages
English (en)
Inventor
Dr Stefan Petry
Dr Karl-Heinz Baringhaus
Dr Norbert Tennagels
Dr Guenter Mueller
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of UY28443A1 publication Critical patent/UY28443A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

La invención se refiere a compuestos de la fórmula I en la cual los radicales tienen los significados indicados, y a sus sales fisiológicamente aceptables. Los compuestos son adecuados, por ejemplo, como medicamentos para reducir la glucosa en sangre y para la prevención y el tratamiento de la diabetes.
UY28443A 2003-07-28 2004-07-28 Derivados sustituidos del dióxido de tiazol-benzoisotiazol, procedimiento para su preparación y su uso. UY28443A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10334309A DE10334309A1 (de) 2003-07-28 2003-07-28 Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
UY28443A1 true UY28443A1 (es) 2005-02-28

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28443A UY28443A1 (es) 2003-07-28 2004-07-28 Derivados sustituidos del dióxido de tiazol-benzoisotiazol, procedimiento para su preparación y su uso.

Country Status (38)

Country Link
EP (1) EP1651644B1 (es)
JP (1) JP2007500145A (es)
KR (1) KR20060052886A (es)
CN (1) CN100413862C (es)
AR (1) AR045113A1 (es)
AT (1) ATE346065T1 (es)
AU (1) AU2004261370B2 (es)
BR (1) BRPI0412997A (es)
CA (1) CA2533673A1 (es)
CR (1) CR8202A (es)
CY (1) CY1105962T1 (es)
DE (2) DE10334309A1 (es)
DK (1) DK1651644T3 (es)
EC (1) ECSP066326A (es)
ES (1) ES2276319T3 (es)
GT (1) GT200400146A (es)
HK (1) HK1091825A1 (es)
IL (1) IL173289A0 (es)
JO (1) JO2449B1 (es)
MA (1) MA27932A1 (es)
MY (1) MY141197A (es)
NO (1) NO20060908L (es)
NZ (1) NZ544975A (es)
OA (1) OA13198A (es)
PA (1) PA8607201A1 (es)
PE (1) PE20050326A1 (es)
PL (1) PL1651644T3 (es)
PT (1) PT1651644E (es)
RS (1) RS20060015A (es)
RU (1) RU2350613C2 (es)
SA (1) SA04250332B1 (es)
SI (1) SI1651644T1 (es)
TN (1) TNSN06030A1 (es)
TW (1) TW200524923A (es)
UA (1) UA83057C2 (es)
UY (1) UY28443A1 (es)
WO (1) WO2005012295A1 (es)
ZA (1) ZA200510378B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (de) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
PL2402319T3 (pl) 2006-03-31 2018-02-28 Novartis Ag Inhibitory DGAT
BRPI0715160A2 (pt) 2006-08-08 2013-06-11 Sanofi Aventis imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
TW201014822A (en) 2008-07-09 2010-04-16 Sanofi Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
CN102482312A (zh) 2009-08-26 2012-05-30 赛诺菲 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120058A1 (de) 2011-03-08 2012-09-13 Sanofi Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120050A1 (de) 2011-03-08 2012-09-13 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
CO5190696A1 (es) * 1999-06-16 2002-08-29 Smithkline Beecham Corp Antagonistas de los receptores il-8
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
CY1105962T1 (el) 2011-04-06
ZA200510378B (en) 2006-11-29
PE20050326A1 (es) 2005-06-16
EP1651644A1 (de) 2006-05-03
MY141197A (en) 2010-03-31
CN100413862C (zh) 2008-08-27
AU2004261370A1 (en) 2005-02-10
DE10334309A1 (de) 2005-03-03
DK1651644T3 (da) 2007-03-26
RU2006106231A (ru) 2006-06-27
NO20060908L (no) 2006-02-24
CA2533673A1 (en) 2005-02-10
AR045113A1 (es) 2005-10-19
KR20060052886A (ko) 2006-05-19
JP2007500145A (ja) 2007-01-11
GT200400146A (es) 2005-08-12
AU2004261370B2 (en) 2009-07-16
HK1091825A1 (en) 2007-01-26
RS20060015A (en) 2007-12-31
SA04250332B1 (ar) 2008-02-25
EP1651644B1 (de) 2006-11-22
PA8607201A1 (es) 2005-03-03
BRPI0412997A (pt) 2006-10-03
TNSN06030A1 (en) 2007-10-03
WO2005012295A1 (de) 2005-02-10
CR8202A (es) 2008-10-15
DE502004002117D1 (de) 2007-01-04
PL1651644T3 (pl) 2007-03-30
OA13198A (en) 2006-12-13
ECSP066326A (es) 2006-07-28
RU2350613C2 (ru) 2009-03-27
UA83057C2 (ru) 2008-06-10
MA27932A1 (fr) 2006-06-01
PT1651644E (pt) 2007-01-31
NZ544975A (en) 2010-02-26
IL173289A0 (en) 2006-06-11
SI1651644T1 (sl) 2007-02-28
JO2449B1 (en) 2008-10-09
ES2276319T3 (es) 2007-06-16
TW200524923A (en) 2005-08-01
CN1829715A (zh) 2006-09-06
ATE346065T1 (de) 2006-12-15

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