AU2004261370B2 - Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same - Google Patents

Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same Download PDF

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Publication number
AU2004261370B2
AU2004261370B2 AU2004261370A AU2004261370A AU2004261370B2 AU 2004261370 B2 AU2004261370 B2 AU 2004261370B2 AU 2004261370 A AU2004261370 A AU 2004261370A AU 2004261370 A AU2004261370 A AU 2004261370A AU 2004261370 B2 AU2004261370 B2 AU 2004261370B2
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AU
Australia
Prior art keywords
alkyl
alkylene
aryl
cooh
coo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004261370A
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English (en)
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AU2004261370A1 (en
Inventor
Karl-Heinz Baringhaus
Guenter Mueller
Stefan Petry
Norbert Tennagels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
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Sanofi Aventis Deutschland GmbH
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Filing date
Publication date
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Publication of AU2004261370A1 publication Critical patent/AU2004261370A1/en
Application granted granted Critical
Publication of AU2004261370B2 publication Critical patent/AU2004261370B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AU2004261370A 2003-07-28 2004-07-15 Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same Ceased AU2004261370B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10334309.1 2003-07-28
DE10334309A DE10334309A1 (de) 2003-07-28 2003-07-28 Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
PCT/EP2004/007847 WO2005012295A1 (de) 2003-07-28 2004-07-15 Substituierte thiazol-benzoisothiazoldioxidderivative, verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
AU2004261370A1 AU2004261370A1 (en) 2005-02-10
AU2004261370B2 true AU2004261370B2 (en) 2009-07-16

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004261370A Ceased AU2004261370B2 (en) 2003-07-28 2004-07-15 Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same

Country Status (37)

Country Link
EP (1) EP1651644B1 (enExample)
JP (1) JP2007500145A (enExample)
KR (1) KR20060052886A (enExample)
CN (1) CN100413862C (enExample)
AR (1) AR045113A1 (enExample)
AT (1) ATE346065T1 (enExample)
AU (1) AU2004261370B2 (enExample)
BR (1) BRPI0412997A (enExample)
CA (1) CA2533673A1 (enExample)
CR (1) CR8202A (enExample)
CY (1) CY1105962T1 (enExample)
DE (2) DE10334309A1 (enExample)
DK (1) DK1651644T3 (enExample)
EC (1) ECSP066326A (enExample)
ES (1) ES2276319T3 (enExample)
GT (1) GT200400146A (enExample)
IL (1) IL173289A0 (enExample)
JO (1) JO2449B1 (enExample)
MA (1) MA27932A1 (enExample)
MY (1) MY141197A (enExample)
NO (1) NO20060908L (enExample)
NZ (1) NZ544975A (enExample)
OA (1) OA13198A (enExample)
PA (1) PA8607201A1 (enExample)
PE (1) PE20050326A1 (enExample)
PL (1) PL1651644T3 (enExample)
PT (1) PT1651644E (enExample)
RS (1) RS20060015A (enExample)
RU (1) RU2350613C2 (enExample)
SA (1) SA04250332B1 (enExample)
SI (1) SI1651644T1 (enExample)
TN (1) TNSN06030A1 (enExample)
TW (1) TW200524923A (enExample)
UA (1) UA83057C2 (enExample)
UY (1) UY28443A1 (enExample)
WO (1) WO2005012295A1 (enExample)
ZA (1) ZA200510378B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (de) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
EP2301923B1 (en) 2006-03-31 2016-06-08 Novartis AG Pyridine derivatives as dgat inhibitors
EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US8470841B2 (en) 2008-07-09 2013-06-25 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
CN102482312A (zh) 2009-08-26 2012-05-30 赛诺菲 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2025017207A1 (en) * 2023-07-20 2025-01-23 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh Inhibitors of smndc1 and their therapeutic use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
PL183919B1 (pl) * 1995-06-02 2002-08-30 Sanofi Synthelabo Pochodne oksazolidynonu, sposób ich otrzymywania oraz ich farmaceutyczne zastosowanie
CO5190696A1 (es) * 1999-06-16 2002-08-29 Smithkline Beecham Corp Antagonistas de los receptores il-8
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
ECSP066326A (es) 2006-07-28
ZA200510378B (en) 2006-11-29
CN100413862C (zh) 2008-08-27
NO20060908L (no) 2006-02-24
EP1651644A1 (de) 2006-05-03
BRPI0412997A (pt) 2006-10-03
UA83057C2 (ru) 2008-06-10
DE10334309A1 (de) 2005-03-03
WO2005012295A1 (de) 2005-02-10
ES2276319T3 (es) 2007-06-16
PT1651644E (pt) 2007-01-31
ATE346065T1 (de) 2006-12-15
CN1829715A (zh) 2006-09-06
PL1651644T3 (pl) 2007-03-30
PE20050326A1 (es) 2005-06-16
SI1651644T1 (sl) 2007-02-28
CR8202A (es) 2008-10-15
IL173289A0 (en) 2006-06-11
CY1105962T1 (el) 2011-04-06
JP2007500145A (ja) 2007-01-11
AR045113A1 (es) 2005-10-19
JO2449B1 (en) 2008-10-09
TNSN06030A1 (en) 2007-10-03
CA2533673A1 (en) 2005-02-10
RU2350613C2 (ru) 2009-03-27
OA13198A (en) 2006-12-13
DE502004002117D1 (de) 2007-01-04
AU2004261370A1 (en) 2005-02-10
DK1651644T3 (da) 2007-03-26
EP1651644B1 (de) 2006-11-22
HK1091825A1 (en) 2007-01-26
MY141197A (en) 2010-03-31
SA04250332B1 (ar) 2008-02-25
TW200524923A (en) 2005-08-01
PA8607201A1 (es) 2005-03-03
MA27932A1 (fr) 2006-06-01
GT200400146A (es) 2005-08-12
KR20060052886A (ko) 2006-05-19
UY28443A1 (es) 2005-02-28
NZ544975A (en) 2010-02-26
RS20060015A (sr) 2007-12-31
RU2006106231A (ru) 2006-06-27

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired