DE10106214A1 - Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz - Google Patents

Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz

Info

Publication number
DE10106214A1
DE10106214A1 DE10106214A DE10106214A DE10106214A1 DE 10106214 A1 DE10106214 A1 DE 10106214A1 DE 10106214 A DE10106214 A DE 10106214A DE 10106214 A DE10106214 A DE 10106214A DE 10106214 A1 DE10106214 A1 DE 10106214A1
Authority
DE
Germany
Prior art keywords
iminoimidazolidine
phen
isopropyl
tert
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10106214A
Other languages
German (de)
English (en)
Inventor
Franz Esser
Pascale Arielle Jane-Jo Pouzet
Hisato Kitagawa
Kenji Sakai
Ikunobu Muramatsu
Matthias Hoffmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Priority to DE10106214A priority Critical patent/DE10106214A1/de
Priority to MXPA03007127A priority patent/MXPA03007127A/es
Priority to EA200300835A priority patent/EA200300835A1/ru
Priority to EP02704665A priority patent/EP1362038A1/de
Priority to BR0206949-0A priority patent/BR0206949A/pt
Priority to JP2002564503A priority patent/JP2004517963A/ja
Priority to CNA02804570XA priority patent/CN1491216A/zh
Priority to KR10-2003-7010280A priority patent/KR20030076653A/ko
Priority to CZ20032146A priority patent/CZ20032146A3/cs
Priority to PCT/EP2002/000576 priority patent/WO2002064570A1/de
Priority to SK1013-2003A priority patent/SK10132003A3/sk
Priority to CA002437809A priority patent/CA2437809A1/en
Priority to HU0303004A priority patent/HUP0303004A3/hu
Priority to PL36214902A priority patent/PL362149A1/xx
Priority to EEP200300379A priority patent/EE200300379A/xx
Priority to IL15729702A priority patent/IL157297A0/xx
Priority to US10/058,456 priority patent/US20020169193A1/en
Priority to ARP020100417A priority patent/AR035226A1/es
Publication of DE10106214A1 publication Critical patent/DE10106214A1/de
Priority to ZA200305609A priority patent/ZA200305609B/en
Priority to EC2003004700A priority patent/ECSP034700A/es
Priority to BG108036A priority patent/BG108036A/bg
Priority to NO20033368A priority patent/NO20033368D0/no
Priority to US11/006,375 priority patent/US20050085522A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE10106214A 2001-02-10 2001-02-10 Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz Withdrawn DE10106214A1 (de)

Priority Applications (23)

Application Number Priority Date Filing Date Title
DE10106214A DE10106214A1 (de) 2001-02-10 2001-02-10 Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz
CA002437809A CA2437809A1 (en) 2001-02-10 2002-01-22 Novel alkyl phenylimino-imidazolidine derivatives for treating urinary incontinence
CZ20032146A CZ20032146A3 (cs) 2001-02-10 2002-01-22 Imidazolidinové deriváty a jejich použití
EP02704665A EP1362038A1 (de) 2001-02-10 2002-01-22 Neue alkyl-phenylimino-imidazolidin-derivate zur behandlung der harninkontinenz
BR0206949-0A BR0206949A (pt) 2001-02-10 2002-01-22 Derivados de alquil-fenilimino-imidazolidina para tratamento de incontinência urinária
JP2002564503A JP2004517963A (ja) 2001-02-10 2002-01-22 尿失禁治療用の新規なアルキル−フェニルイミノイミダゾリジン誘導体
CNA02804570XA CN1491216A (zh) 2001-02-10 2002-01-22 用于治疗尿失禁的新颖烷基苯基亚氨咪唑烷衍生物
KR10-2003-7010280A KR20030076653A (ko) 2001-02-10 2002-01-22 요실금의 치료를 위한 신규한알킬-페닐이미노-이미다졸리딘 유도체
EA200300835A EA200300835A1 (ru) 2001-02-10 2002-01-22 Новые производные алкилфенилиминоимидазолидина для лечения недержания мочи
PCT/EP2002/000576 WO2002064570A1 (de) 2001-02-10 2002-01-22 Neue alkyl-phenylimino-imidazolidin-derivate zur behandlung der harninkontinenz
SK1013-2003A SK10132003A3 (sk) 2001-02-10 2002-01-22 Alkylfenyliminoimidazolidínové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
MXPA03007127A MXPA03007127A (es) 2001-02-10 2002-01-22 Nuevos derivados de alquil-fenilimino-imidazolidina para tratamiento de incontinencia urinaria.
HU0303004A HUP0303004A3 (en) 2001-02-10 2002-01-22 Novel alkyl phenylimino-imidazolidine derivatives, pharmaceutical compositions containing them and their use for preparation of for treating urinary incontinence
IL15729702A IL157297A0 (en) 2001-02-10 2002-01-22 Novel alkyl phenylimino-imidazolidine derivatives for treating urinary incontinence
EEP200300379A EE200300379A (et) 2001-02-10 2002-01-22 Alküülfenüüliminoimidasolidiini derivaadid uriinipidamatuse ravimiseks
PL36214902A PL362149A1 (en) 2001-02-10 2002-01-22 Novel alkyl phenylimino-imidazolidine derivatives for treating urinary incontinence
US10/058,456 US20020169193A1 (en) 2001-02-10 2002-01-28 Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence
ARP020100417A AR035226A1 (es) 2001-02-10 2002-02-08 Derivados de alquil-fenilimino-imidazolidina para el tratamiento de la incontinencia urinaria.
ZA200305609A ZA200305609B (en) 2001-02-10 2003-07-21 Novel-alkyl-phenylimino-imidazolidine derivatives for treating urinary incontinence.
EC2003004700A ECSP034700A (es) 2001-02-10 2003-07-22 Nuevos derivados de m-alquil-fenilimino-imidazolidana para tratar la incontinencia urinaria
BG108036A BG108036A (bg) 2001-02-10 2003-07-28 Нови алкил-фенилимино-имидазолидинови производни за лечение на инконтиненция
NO20033368A NO20033368D0 (no) 2001-02-10 2003-07-28 Nye alkyl-fenylimino-imidazolidin-derivater for behandling av urin-inkontinens
US11/006,375 US20050085522A1 (en) 2001-02-10 2004-12-07 Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10106214A DE10106214A1 (de) 2001-02-10 2001-02-10 Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz

Publications (1)

Publication Number Publication Date
DE10106214A1 true DE10106214A1 (de) 2002-08-14

Family

ID=7673601

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10106214A Withdrawn DE10106214A1 (de) 2001-02-10 2001-02-10 Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz

Country Status (21)

Country Link
EP (1) EP1362038A1 (hu)
JP (1) JP2004517963A (hu)
KR (1) KR20030076653A (hu)
CN (1) CN1491216A (hu)
AR (1) AR035226A1 (hu)
BG (1) BG108036A (hu)
BR (1) BR0206949A (hu)
CA (1) CA2437809A1 (hu)
CZ (1) CZ20032146A3 (hu)
DE (1) DE10106214A1 (hu)
EA (1) EA200300835A1 (hu)
EC (1) ECSP034700A (hu)
EE (1) EE200300379A (hu)
HU (1) HUP0303004A3 (hu)
IL (1) IL157297A0 (hu)
MX (1) MXPA03007127A (hu)
NO (1) NO20033368D0 (hu)
PL (1) PL362149A1 (hu)
SK (1) SK10132003A3 (hu)
WO (1) WO2002064570A1 (hu)
ZA (1) ZA200305609B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100378097C (zh) * 2003-05-09 2008-04-02 弗·哈夫曼-拉罗切有限公司 作为α-1肾上腺素能激动剂的甲基吲哚和甲基吡咯并吡啶
JP4168086B1 (ja) * 2008-04-16 2008-10-22 国立大学法人福井大学 イミダゾリン誘導体

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) * 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
DE3518604A1 (de) * 1984-05-23 1985-11-28 Egyt Gyógyszervegyészeti Gyár, Budapest Verfahren zur herstellung von 2-(phenylimino)-imidazolidinderivaten
WO1996032939A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg VERWENDUNG VON α1L-AGONISTEN ZUR BEHANDLUNG DER HARNINKONTINENZ
WO1998042679A1 (fr) * 1997-03-20 1998-10-01 Sanofi-Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
US5952362A (en) * 1997-06-23 1999-09-14 Syntex (U.S.A) Inc. 2-imidazoline, 2-oxazoline, 2-thiazoline, and 4-imidazole derivatives of methylphenyl, methoxyphenyl, and aminophenyl alkylsulfonamides and ureas and their use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) * 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
DE3518604A1 (de) * 1984-05-23 1985-11-28 Egyt Gyógyszervegyészeti Gyár, Budapest Verfahren zur herstellung von 2-(phenylimino)-imidazolidinderivaten
WO1996032939A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg VERWENDUNG VON α1L-AGONISTEN ZUR BEHANDLUNG DER HARNINKONTINENZ
WO1998042679A1 (fr) * 1997-03-20 1998-10-01 Sanofi-Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
US5952362A (en) * 1997-06-23 1999-09-14 Syntex (U.S.A) Inc. 2-imidazoline, 2-oxazoline, 2-thiazoline, and 4-imidazole derivatives of methylphenyl, methoxyphenyl, and aminophenyl alkylsulfonamides and ureas and their use

Also Published As

Publication number Publication date
CA2437809A1 (en) 2002-08-22
WO2002064570A1 (de) 2002-08-22
EP1362038A1 (de) 2003-11-19
SK10132003A3 (sk) 2004-02-03
AR035226A1 (es) 2004-05-05
MXPA03007127A (es) 2003-11-18
HUP0303004A3 (en) 2004-07-28
CN1491216A (zh) 2004-04-21
BG108036A (bg) 2004-12-30
NO20033368L (no) 2003-07-28
NO20033368D0 (no) 2003-07-28
EE200300379A (et) 2003-12-15
EA200300835A1 (ru) 2004-02-26
KR20030076653A (ko) 2003-09-26
JP2004517963A (ja) 2004-06-17
HUP0303004A2 (hu) 2003-12-29
ECSP034700A (es) 2003-08-29
CZ20032146A3 (cs) 2003-12-17
BR0206949A (pt) 2004-02-25
IL157297A0 (en) 2004-02-19
PL362149A1 (en) 2004-10-18
ZA200305609B (en) 2004-04-29

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Legal Events

Date Code Title Description
OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
8127 New person/name/address of the applicant

Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG, 55218 IN

8141 Disposal/no request for examination