DE01909263T1 - Verbindung mit Chelationsaffinität und Selektivität für Elemente der ersten Übergangselement-Reihe - Google Patents
Verbindung mit Chelationsaffinität und Selektivität für Elemente der ersten Übergangselement-Reihe Download PDFInfo
- Publication number
- DE01909263T1 DE01909263T1 DE0001261349T DE01909263T DE01909263T1 DE 01909263 T1 DE01909263 T1 DE 01909263T1 DE 0001261349 T DE0001261349 T DE 0001261349T DE 01909263 T DE01909263 T DE 01909263T DE 01909263 T1 DE01909263 T1 DE 01909263T1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- interrupted
- alkenyl
- group
- oxa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000007704 transition Effects 0.000 title claims abstract 6
- 230000009920 chelation Effects 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 11
- 206010063837 Reperfusion injury Diseases 0.000 claims abstract 3
- 239000002537 cosmetic Substances 0.000 claims abstract 3
- 208000002925 dental caries Diseases 0.000 claims abstract 3
- 208000024693 gingival disease Diseases 0.000 claims abstract 3
- 230000004792 oxidative damage Effects 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 140
- 125000003342 alkenyl group Chemical group 0.000 claims 97
- 125000003118 aryl group Chemical group 0.000 claims 70
- 241000534944 Thia Species 0.000 claims 61
- 125000004171 alkoxy aryl group Chemical group 0.000 claims 60
- 125000003545 alkoxy group Chemical group 0.000 claims 60
- -1 aminoarylalkyl Chemical group 0.000 claims 60
- 125000005160 aryl oxy alkyl group Chemical group 0.000 claims 46
- 125000003302 alkenyloxy group Chemical group 0.000 claims 40
- 125000005108 alkenylthio group Chemical group 0.000 claims 40
- 125000004414 alkyl thio group Chemical group 0.000 claims 40
- 125000005021 aminoalkenyl group Chemical group 0.000 claims 40
- 125000004103 aminoalkyl group Chemical group 0.000 claims 40
- 125000005001 aminoaryl group Chemical group 0.000 claims 40
- 125000003710 aryl alkyl group Chemical group 0.000 claims 40
- 125000004104 aryloxy group Chemical group 0.000 claims 40
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 39
- 239000008139 complexing agent Substances 0.000 claims 35
- 125000005020 hydroxyalkenyl group Chemical group 0.000 claims 35
- 125000005110 aryl thio group Chemical group 0.000 claims 29
- 125000005027 hydroxyaryl group Chemical group 0.000 claims 28
- 239000000539 dimer Substances 0.000 claims 20
- 229910052736 halogen Inorganic materials 0.000 claims 12
- 125000005843 halogen group Chemical group 0.000 claims 12
- 125000004432 carbon atom Chemical group C* 0.000 claims 10
- 125000005647 linker group Chemical group 0.000 claims 10
- LLKJIZGVRHHRQB-UHFFFAOYSA-N [4,7-bis(phosphonomethyl)-1,4,7-triazonan-1-yl]methylphosphonic acid Chemical compound OP(O)(=O)CN1CCN(CP(O)(O)=O)CCN(CP(O)(O)=O)CC1 LLKJIZGVRHHRQB-UHFFFAOYSA-N 0.000 claims 5
- 125000004948 alkyl aryl alkyl group Chemical group 0.000 claims 4
- 150000002367 halogens Chemical class 0.000 claims 4
- 150000001336 alkenes Chemical class 0.000 claims 3
- 125000004946 alkenylalkyl group Chemical group 0.000 claims 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 3
- 125000001412 tetrahydropyranyl group Chemical group 0.000 claims 3
- 208000035985 Body Odor Diseases 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 150000001768 cations Chemical class 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 208000028169 periodontal disease Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000005764 inhibitory process Effects 0.000 abstract 3
- 230000000813 microbial effect Effects 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 0 CCCCCCN(*)C[C@](C)* Chemical compound CCCCCCN(*)C[C@](C)* 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/51—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US510134 | 1983-07-01 | ||
| US09/510,134 US6264966B1 (en) | 2000-02-22 | 2000-02-22 | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
| PCT/US2001/004977 WO2001062262A1 (en) | 2000-02-22 | 2001-02-14 | Compounds with chelation affinity and selectivity for first transition series elements and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE01909263T1 true DE01909263T1 (de) | 2004-08-26 |
Family
ID=24029507
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE0001261349T Pending DE01909263T1 (de) | 2000-02-22 | 2001-02-14 | Verbindung mit Chelationsaffinität und Selektivität für Elemente der ersten Übergangselement-Reihe |
| DE60135638T Expired - Lifetime DE60135638D1 (de) | 2000-02-22 | 2001-02-14 | Verbindung mit chelationsaffinität und selektivitäe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60135638T Expired - Lifetime DE60135638D1 (de) | 2000-02-22 | 2001-02-14 | Verbindung mit chelationsaffinität und selektivitäe |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6264966B1 (enExample) |
| EP (2) | EP1261349B1 (enExample) |
| JP (1) | JP2003523394A (enExample) |
| AT (1) | ATE406902T1 (enExample) |
| AU (1) | AU2001237038A1 (enExample) |
| CA (1) | CA2399299C (enExample) |
| DE (2) | DE01909263T1 (enExample) |
| ES (1) | ES2239924T1 (enExample) |
| IL (2) | IL151031A0 (enExample) |
| WO (1) | WO2001062262A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7592304B2 (en) * | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US20030130185A1 (en) * | 2000-09-29 | 2003-07-10 | David Bar-Or | Metal-binding compounds and uses therefor |
| US20030158111A1 (en) * | 1999-10-01 | 2003-08-21 | David Bar-Or | Methods and products for oral care |
| US7632803B2 (en) * | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| MXPA02006338A (es) | 1999-12-24 | 2002-12-13 | Aventis Pharma Ltd | Azaindoles. |
| US6264966B1 (en) * | 2000-02-22 | 2001-07-24 | Concat, Ltd. | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
| US6881732B2 (en) * | 2002-06-13 | 2005-04-19 | Chelator Llc | Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements |
| EP1620066A4 (en) * | 2003-05-07 | 2010-11-03 | Dmi Biosciences Inc | ORAL CARE PROCESSES AND PRODUCTS |
| US20050112066A1 (en) * | 2003-11-26 | 2005-05-26 | Concat Lp, A California Limited Partnership | Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity |
| US7659233B2 (en) * | 2004-10-25 | 2010-02-09 | Conopco, Inc. | Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts |
| US8476251B2 (en) | 2010-07-29 | 2013-07-02 | Conopco, Inc. | Skin care compositions comprising substituted diamines |
| US8293218B2 (en) | 2010-07-29 | 2012-10-23 | Conopco, Inc. | Skin care compositions comprising substituted monoamines |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| CN103086922A (zh) * | 2013-02-07 | 2013-05-08 | 东华大学 | 一种n-烷氧基-4-戊烯酰胺类化合物及其制备方法 |
| KR101709124B1 (ko) * | 2015-08-19 | 2017-02-22 | 기초과학연구원 | 신규한 키랄 금속 착물 및 분광법에 의해 전하를 띤 화합물의 키랄성을 분석하기 위한 이의 용도 |
| EP3390348B1 (en) | 2015-12-16 | 2024-04-17 | Loveland Products, Inc. | Dendrimer and formulations thereof |
| JP7191938B2 (ja) | 2017-05-05 | 2022-12-19 | センター・フォー・プローブ・デベロップメント・アンド・コマーシャライゼイション | Ｉｇｆ－１ｒモノクローナル抗体及びその使用 |
| US10093741B1 (en) | 2017-05-05 | 2018-10-09 | Fusion Pharmaceuticals Inc. | IGF-1R monoclonal antibodies and uses thereof |
| RU2019139432A (ru) | 2017-05-05 | 2021-06-07 | Сентр фор Проуб Девелопмент энд Коммерсиализэйшн | Фармакокинетическая оптимизация бифункциональных хелатов и их применение |
| US11373803B2 (en) | 2017-08-11 | 2022-06-28 | Applied Materials, Inc. | Method of forming a magnetic core on a substrate |
| WO2020102820A1 (en) | 2018-11-16 | 2020-05-22 | The Research Foundation For The State University Of New York | Compounds for use as iron (iii) mri contrast agents containing anionic pendents and ancillary groups |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356190A (en) * | 1974-06-12 | 1982-10-26 | Personal Products Company | Inhibiting production of undesirable products on body surfaces and environs employing aminopolycarboxylic compounds |
| JPS62238213A (ja) * | 1986-04-04 | 1987-10-19 | Maab:Kk | 脱臭用清浄布収納パツク |
| JPH0825861B2 (ja) * | 1989-04-24 | 1996-03-13 | サンスター株式会社 | 歯磨組成物 |
| US5236695A (en) | 1989-11-27 | 1993-08-17 | Concat, Ltd. | MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands |
| US5147632A (en) * | 1990-10-31 | 1992-09-15 | Warner-Lambert Company | Anti-plaque compositions comprising a combination of morpholinoamino alcohol and chelating agent |
| WO1993011741A1 (en) * | 1991-12-10 | 1993-06-24 | The Dow Chemical Company | Oral compositions for inhibiting plaque and calculus formation |
| US5409689A (en) | 1993-08-13 | 1995-04-25 | Concat, Ltd. | MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms |
| US6525041B1 (en) * | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| EP0841951A2 (en) | 1995-06-26 | 1998-05-20 | Concat Ltd. | Compounds with chelation affinity and selectivity for first transition series elements, and their use in medical therapy and diagnosis |
| FR2737204B1 (fr) * | 1995-07-26 | 1997-09-12 | Oreal | Derives de n,n'-di(aralkyl)n,n'-di(carboxylakyl)alkylene di- ou triamine et de n-(aralkyl)n'-(carboxyalkyl) n,n'-di(carboxyalkyl)alkylene di- ou triamine et leur utilisation en pharmacie et en cosmetique |
| FR2749845B1 (fr) * | 1996-06-18 | 1998-08-21 | Oreal | Nouveaux derives benzyl substitue(s) de polyalkylene-polyamines et leur utilisation dans des compositions cosmetiques et pharmaceutiques |
| US6165966A (en) * | 1996-09-24 | 2000-12-26 | The Procter & Gamble Company | Liquid detergents containing proteolytic enzyme and protease inhibitors |
| DE60129791T2 (de) * | 2000-01-18 | 2008-04-30 | Unilever N.V. | Antimikrobielle zubereitung salz eines übergangmetall-chelators enthaltend |
| GB0001129D0 (en) * | 2000-01-18 | 2000-03-08 | Unilever Plc | Anti-microbial aerosol compositions |
| US6264966B1 (en) * | 2000-02-22 | 2001-07-24 | Concat, Ltd. | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
-
2000
- 2000-02-22 US US09/510,134 patent/US6264966B1/en not_active Expired - Fee Related
-
2001
- 2001-02-14 CA CA002399299A patent/CA2399299C/en not_active Expired - Fee Related
- 2001-02-14 ES ES01909263T patent/ES2239924T1/es active Pending
- 2001-02-14 AU AU2001237038A patent/AU2001237038A1/en not_active Abandoned
- 2001-02-14 EP EP01909263A patent/EP1261349B1/en not_active Expired - Lifetime
- 2001-02-14 DE DE0001261349T patent/DE01909263T1/de active Pending
- 2001-02-14 JP JP2001561327A patent/JP2003523394A/ja active Pending
- 2001-02-14 WO PCT/US2001/004977 patent/WO2001062262A1/en not_active Ceased
- 2001-02-14 DE DE60135638T patent/DE60135638D1/de not_active Expired - Lifetime
- 2001-02-14 IL IL15103101A patent/IL151031A0/xx unknown
- 2001-02-14 AT AT01909263T patent/ATE406902T1/de not_active IP Right Cessation
- 2001-02-14 EP EP08162900A patent/EP2011501A1/en not_active Withdrawn
- 2001-04-20 US US09/839,970 patent/US6387891B2/en not_active Expired - Fee Related
-
2002
- 2002-08-01 IL IL151031A patent/IL151031A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1261349B1 (en) | 2008-09-03 |
| AU2001237038A1 (en) | 2001-09-03 |
| CA2399299C (en) | 2009-11-17 |
| EP1261349A1 (en) | 2002-12-04 |
| EP1261349A4 (en) | 2004-09-01 |
| IL151031A (en) | 2009-06-15 |
| IL151031A0 (en) | 2003-04-10 |
| US6264966B1 (en) | 2001-07-24 |
| CA2399299A1 (en) | 2001-08-30 |
| US6387891B2 (en) | 2002-05-14 |
| US20010041170A1 (en) | 2001-11-15 |
| DE60135638D1 (de) | 2008-10-16 |
| EP2011501A1 (en) | 2009-01-07 |
| WO2001062262A1 (en) | 2001-08-30 |
| ATE406902T1 (de) | 2008-09-15 |
| ES2239924T1 (es) | 2005-10-16 |
| JP2003523394A (ja) | 2003-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE01909263T1 (de) | Verbindung mit Chelationsaffinität und Selektivität für Elemente der ersten Übergangselement-Reihe | |
| JP2003523394A5 (enExample) | ||
| DE60115869T2 (de) | Zusammensetzungen und verfahren zur behandlung von haarausfall unter verwendung von c16-c20 aromatischen tetrahydro-prostaglandinen | |
| EP1609361A3 (de) | Mittel zur Bekämpfung von Pflanzenschädlingen | |
| EP0470127A4 (en) | Pcp receptor ligands and the use thereof | |
| ATE243702T1 (de) | Verfahren zur herstellung von ascorbinsäurederivaten | |
| ATE147725T1 (de) | Biguanidederivate, verfahren zu ihrer herstellung und diese enthaltende desinfektionsmittel | |
| OA09212A (fr) | Lauramides N-substitués, leur préparation et compositions les contenant. | |
| DE69110125T2 (de) | Zahnpasta gegen zahnbelag. | |
| SI2017276T1 (sl) | Fenil-karboksamidne spojine, uporabne za tretiranje bolečine | |
| DE68917678D1 (de) | Verfahren und Mittel zur Behandlung der Alzheimer-Krankheit, verwandter Demenzen und Epilepsie. | |
| DE3866652D1 (de) | (benzylpiperidino)-1-propanol-derivate, ihre herstellung, ihre anwendung als mikrobizide und zusammensetzungen, die sie enthalten. | |
| DE2341471C2 (de) | Verwendung eines Alkylen- oder Polyalkylenglykols als Stabilisierungsmittel für eine eine Organothiophosphorverbindung und ein Desodorisierungsmittel enthaltende Zusammensetzung | |
| EP0966256A1 (de) | Mittel zur förderung der mundhygiene und der mundgesundheit | |
| KR950703527A (ko) | 프로스타글란딘 유도체 | |
| DE60018730T2 (de) | Antiperspirantien und deodoranten, die cyclohexasiloxanen enthalten | |
| FR2646601B1 (fr) | Dentifrice et compositions orales utiles pour inhiber les calculs dentaires | |
| JPH06509081A (ja) | 粉末状体臭除去組成物 | |
| EP0117905A2 (de) | Mundpflegemittel | |
| EP0238943A3 (de) | Fungizide Mittel auf der Basis von Triazolderivaten | |
| KR900009044A (ko) | 착색을 감소시키면서 프라그를 감소시키기 위한 경구 치료방법 | |
| CN115361936B (zh) | 口腔用组合物 | |
| ATE321553T1 (de) | Arzneimittel für hinterstrangataxie und zusammensetzung zur behandlung von hinterstrangataxie | |
| DE2529271A1 (de) | Mund- und zahnpflegemittel, insbesondere zur bekaempfung der parodontose | |
| DE551844T1 (de) | Thiolderivate von Gallensäure. |