ATE406902T1 - Verbindung mit chelationsaffinität und selektivität für elemente der ersten transitionselementenserie - Google Patents

Verbindung mit chelationsaffinität und selektivität für elemente der ersten transitionselementenserie

Info

Publication number
ATE406902T1
ATE406902T1 AT01909263T AT01909263T ATE406902T1 AT E406902 T1 ATE406902 T1 AT E406902T1 AT 01909263 T AT01909263 T AT 01909263T AT 01909263 T AT01909263 T AT 01909263T AT E406902 T1 ATE406902 T1 AT E406902T1
Authority
AT
Austria
Prior art keywords
inhibition
decrease
selectivity
series elements
transition series
Prior art date
Application number
AT01909263T
Other languages
German (de)
English (en)
Inventor
Harry Winchell
Joseph Klein
Elliot Simhon
Rosa Cyjon
Ofer Klein
Haim Zaklad
Original Assignee
Chelator Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chelator Llc filed Critical Chelator Llc
Application granted granted Critical
Publication of ATE406902T1 publication Critical patent/ATE406902T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AT01909263T 2000-02-22 2001-02-14 Verbindung mit chelationsaffinität und selektivität für elemente der ersten transitionselementenserie ATE406902T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/510,134 US6264966B1 (en) 2000-02-22 2000-02-22 Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury

Publications (1)

Publication Number Publication Date
ATE406902T1 true ATE406902T1 (de) 2008-09-15

Family

ID=24029507

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01909263T ATE406902T1 (de) 2000-02-22 2001-02-14 Verbindung mit chelationsaffinität und selektivität für elemente der ersten transitionselementenserie

Country Status (10)

Country Link
US (2) US6264966B1 (enExample)
EP (2) EP1261349B1 (enExample)
JP (1) JP2003523394A (enExample)
AT (1) ATE406902T1 (enExample)
AU (1) AU2001237038A1 (enExample)
CA (1) CA2399299C (enExample)
DE (2) DE01909263T1 (enExample)
ES (1) ES2239924T1 (enExample)
IL (2) IL151031A0 (enExample)
WO (1) WO2001062262A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030130185A1 (en) * 2000-09-29 2003-07-10 David Bar-Or Metal-binding compounds and uses therefor
US20030158111A1 (en) * 1999-10-01 2003-08-21 David Bar-Or Methods and products for oral care
US7632803B2 (en) * 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US7592304B2 (en) * 1999-10-01 2009-09-22 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
NZ519121A (en) 1999-12-24 2004-05-28 Aventis Pharma Ltd Azaindoles useful as Syk kinase inhibitors
US6264966B1 (en) * 2000-02-22 2001-07-24 Concat, Ltd. Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury
US6881732B2 (en) * 2002-06-13 2005-04-19 Chelator Llc Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements
JP2006528690A (ja) * 2003-05-07 2006-12-21 ディーエムアイ バイオサイエンシズ インコーポレイテッド 口腔ケア方法および製品
US20050112066A1 (en) * 2003-11-26 2005-05-26 Concat Lp, A California Limited Partnership Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity
US7659233B2 (en) * 2004-10-25 2010-02-09 Conopco, Inc. Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts
US8476251B2 (en) 2010-07-29 2013-07-02 Conopco, Inc. Skin care compositions comprising substituted diamines
US8293218B2 (en) 2010-07-29 2012-10-23 Conopco, Inc. Skin care compositions comprising substituted monoamines
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof
CN103086922A (zh) * 2013-02-07 2013-05-08 东华大学 一种n-烷氧基-4-戊烯酰胺类化合物及其制备方法
KR101709124B1 (ko) * 2015-08-19 2017-02-22 기초과학연구원 신규한 키랄 금속 착물 및 분광법에 의해 전하를 띤 화합물의 키랄성을 분석하기 위한 이의 용도
ES2986022T3 (es) 2015-12-16 2024-11-08 Loveland Products Inc Dendrímero y sus formulaciones
IL270453B2 (en) 2017-05-05 2025-05-01 Fusion Pharmaceuticals Inc Pharmacokinetic enhancements of bifunctional chelates and uses thereof
CN110891614A (zh) 2017-05-05 2020-03-17 融合制药公司 Igf-1r单克隆抗体及其用途
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
US11373803B2 (en) 2017-08-11 2022-06-28 Applied Materials, Inc. Method of forming a magnetic core on a substrate
US11344635B2 (en) 2018-11-16 2022-05-31 The Research Foundation For The State University Of New York Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356190A (en) * 1974-06-12 1982-10-26 Personal Products Company Inhibiting production of undesirable products on body surfaces and environs employing aminopolycarboxylic compounds
JPS62238213A (ja) * 1986-04-04 1987-10-19 Maab:Kk 脱臭用清浄布収納パツク
JPH0825861B2 (ja) * 1989-04-24 1996-03-13 サンスター株式会社 歯磨組成物
US5236695A (en) 1989-11-27 1993-08-17 Concat, Ltd. MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands
US5147632A (en) * 1990-10-31 1992-09-15 Warner-Lambert Company Anti-plaque compositions comprising a combination of morpholinoamino alcohol and chelating agent
CA2125576A1 (en) * 1991-12-10 1993-06-24 Joseph R. Garlich Oral compositions for inhibiting plaque and calculus formation
US5409689A (en) 1993-08-13 1995-04-25 Concat, Ltd. MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
CN1203899C (zh) * 1995-06-26 2005-06-01 螯合剂有限公司 对第一过渡系元素具有螯合亲和力和选择性的化合物及它们在医学冶疗中的用途
FR2737204B1 (fr) * 1995-07-26 1997-09-12 Oreal Derives de n,n'-di(aralkyl)n,n'-di(carboxylakyl)alkylene di- ou triamine et de n-(aralkyl)n'-(carboxyalkyl) n,n'-di(carboxyalkyl)alkylene di- ou triamine et leur utilisation en pharmacie et en cosmetique
FR2749845B1 (fr) * 1996-06-18 1998-08-21 Oreal Nouveaux derives benzyl substitue(s) de polyalkylene-polyamines et leur utilisation dans des compositions cosmetiques et pharmaceutiques
US6165966A (en) * 1996-09-24 2000-12-26 The Procter & Gamble Company Liquid detergents containing proteolytic enzyme and protease inhibitors
GB0001129D0 (en) * 2000-01-18 2000-03-08 Unilever Plc Anti-microbial aerosol compositions
WO2001052805A1 (en) * 2000-01-18 2001-07-26 Unilever Plc Anti-microbial compositions comprising a salt of a transition metal chelator
US6264966B1 (en) * 2000-02-22 2001-07-24 Concat, Ltd. Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury

Also Published As

Publication number Publication date
ES2239924T1 (es) 2005-10-16
IL151031A0 (en) 2003-04-10
EP2011501A1 (en) 2009-01-07
WO2001062262A1 (en) 2001-08-30
JP2003523394A (ja) 2003-08-05
US6264966B1 (en) 2001-07-24
US20010041170A1 (en) 2001-11-15
DE01909263T1 (de) 2004-08-26
AU2001237038A1 (en) 2001-09-03
DE60135638D1 (de) 2008-10-16
CA2399299A1 (en) 2001-08-30
EP1261349A1 (en) 2002-12-04
EP1261349B1 (en) 2008-09-03
CA2399299C (en) 2009-11-17
EP1261349A4 (en) 2004-09-01
US6387891B2 (en) 2002-05-14
IL151031A (en) 2009-06-15

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties