JP2003523394A5 - - Google Patents
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- Publication number
- JP2003523394A5 JP2003523394A5 JP2001561327A JP2001561327A JP2003523394A5 JP 2003523394 A5 JP2003523394 A5 JP 2003523394A5 JP 2001561327 A JP2001561327 A JP 2001561327A JP 2001561327 A JP2001561327 A JP 2001561327A JP 2003523394 A5 JP2003523394 A5 JP 2003523394A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- intercalated
- alkenyl
- group
- oxa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 claims 143
- 125000003342 alkenyl group Chemical group 0.000 claims 110
- -1 alkenoxy Chemical group 0.000 claims 100
- 125000003118 aryl group Chemical group 0.000 claims 77
- 241000534944 Thia Species 0.000 claims 66
- 125000003545 alkoxy group Chemical group 0.000 claims 66
- 125000004171 alkoxy aryl group Chemical group 0.000 claims 56
- 125000005160 aryl oxy alkyl group Chemical group 0.000 claims 55
- 125000005108 alkenylthio group Chemical group 0.000 claims 44
- 125000004414 alkyl thio group Chemical group 0.000 claims 44
- 125000005021 aminoalkenyl group Chemical group 0.000 claims 44
- 125000004103 aminoalkyl group Chemical group 0.000 claims 44
- 125000005001 aminoaryl group Chemical group 0.000 claims 44
- 125000003710 aryl alkyl group Chemical group 0.000 claims 44
- 125000004104 aryloxy group Chemical group 0.000 claims 44
- 125000005020 hydroxyalkenyl group Chemical group 0.000 claims 44
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 44
- 125000005027 hydroxyaryl group Chemical group 0.000 claims 44
- 125000005110 aryl thio group Chemical group 0.000 claims 33
- 239000008139 complexing agent Substances 0.000 claims 27
- 125000004122 cyclic group Chemical group 0.000 claims 22
- 239000000539 dimer Substances 0.000 claims 17
- 125000003302 alkenyloxy group Chemical group 0.000 claims 11
- 125000004432 carbon atom Chemical group C* 0.000 claims 11
- 229910052736 halogen Inorganic materials 0.000 claims 11
- 125000005843 halogen group Chemical group 0.000 claims 11
- 125000005647 linker group Chemical group 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 10
- 230000002401 inhibitory effect Effects 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 6
- LLKJIZGVRHHRQB-UHFFFAOYSA-N [4,7-bis(phosphonomethyl)-1,4,7-triazonan-1-yl]methylphosphonic acid Chemical group OP(O)(=O)CN1CCN(CP(O)(O)=O)CCN(CP(O)(O)=O)CC1 LLKJIZGVRHHRQB-UHFFFAOYSA-N 0.000 claims 5
- 239000002537 cosmetic Substances 0.000 claims 4
- 208000035985 Body Odor Diseases 0.000 claims 3
- 206010040904 Skin odour abnormal Diseases 0.000 claims 3
- 206010063837 Reperfusion injury Diseases 0.000 claims 2
- 208000002925 dental caries Diseases 0.000 claims 2
- 208000024693 gingival disease Diseases 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 230000004792 oxidative damage Effects 0.000 claims 1
- 239000002504 physiological saline solution Substances 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
- 229910052723 transition metal Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/510,134 US6264966B1 (en) | 2000-02-22 | 2000-02-22 | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
| US09/510,134 | 2000-02-22 | ||
| PCT/US2001/004977 WO2001062262A1 (en) | 2000-02-22 | 2001-02-14 | Compounds with chelation affinity and selectivity for first transition series elements and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003523394A JP2003523394A (ja) | 2003-08-05 |
| JP2003523394A5 true JP2003523394A5 (enExample) | 2005-04-07 |
Family
ID=24029507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001561327A Pending JP2003523394A (ja) | 2000-02-22 | 2001-02-14 | 第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6264966B1 (enExample) |
| EP (2) | EP2011501A1 (enExample) |
| JP (1) | JP2003523394A (enExample) |
| AT (1) | ATE406902T1 (enExample) |
| AU (1) | AU2001237038A1 (enExample) |
| CA (1) | CA2399299C (enExample) |
| DE (2) | DE60135638D1 (enExample) |
| ES (1) | ES2239924T1 (enExample) |
| IL (2) | IL151031A0 (enExample) |
| WO (1) | WO2001062262A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030158111A1 (en) * | 1999-10-01 | 2003-08-21 | David Bar-Or | Methods and products for oral care |
| US20030130185A1 (en) * | 2000-09-29 | 2003-07-10 | David Bar-Or | Metal-binding compounds and uses therefor |
| US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7592304B2 (en) * | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| CN1615873A (zh) | 1999-12-24 | 2005-05-18 | 阿文蒂斯药物有限公司 | 氮杂吲哚类化合物 |
| US6264966B1 (en) * | 2000-02-22 | 2001-07-24 | Concat, Ltd. | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
| US6881732B2 (en) * | 2002-06-13 | 2005-04-19 | Chelator Llc | Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements |
| US20050002876A1 (en) * | 2003-05-07 | 2005-01-06 | Yukl Richard L. | Oral care methods and products |
| US20050112066A1 (en) * | 2003-11-26 | 2005-05-26 | Concat Lp, A California Limited Partnership | Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity |
| US7659233B2 (en) * | 2004-10-25 | 2010-02-09 | Conopco, Inc. | Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts |
| US8476251B2 (en) | 2010-07-29 | 2013-07-02 | Conopco, Inc. | Skin care compositions comprising substituted diamines |
| US8293218B2 (en) | 2010-07-29 | 2012-10-23 | Conopco, Inc. | Skin care compositions comprising substituted monoamines |
| WO2013082458A1 (en) | 2011-12-02 | 2013-06-06 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| CN103086922A (zh) * | 2013-02-07 | 2013-05-08 | 东华大学 | 一种n-烷氧基-4-戊烯酰胺类化合物及其制备方法 |
| KR101709124B1 (ko) * | 2015-08-19 | 2017-02-22 | 기초과학연구원 | 신규한 키랄 금속 착물 및 분광법에 의해 전하를 띤 화합물의 키랄성을 분석하기 위한 이의 용도 |
| JP6856662B2 (ja) | 2015-12-16 | 2021-04-07 | プライオスター プロプライアタリー リミティド | デンドリマー及びその製剤 |
| BR112019023249A8 (pt) | 2017-05-05 | 2021-02-23 | Centre For Probe Dev And Commercialization | anticorpos monoclonais igf-1r e usos dos mesmos |
| US10093741B1 (en) | 2017-05-05 | 2018-10-09 | Fusion Pharmaceuticals Inc. | IGF-1R monoclonal antibodies and uses thereof |
| IL270453B2 (en) | 2017-05-05 | 2025-05-01 | Fusion Pharmaceuticals Inc | Pharmacokinetic enhancements of bifunctional chelates and uses thereof |
| US11373803B2 (en) | 2017-08-11 | 2022-06-28 | Applied Materials, Inc. | Method of forming a magnetic core on a substrate |
| AU2019381793B2 (en) | 2018-11-16 | 2025-02-27 | The Research Foundation For The State University Of New York | Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356190A (en) * | 1974-06-12 | 1982-10-26 | Personal Products Company | Inhibiting production of undesirable products on body surfaces and environs employing aminopolycarboxylic compounds |
| JPS62238213A (ja) * | 1986-04-04 | 1987-10-19 | Maab:Kk | 脱臭用清浄布収納パツク |
| JPH0825861B2 (ja) * | 1989-04-24 | 1996-03-13 | サンスター株式会社 | 歯磨組成物 |
| US5236695A (en) | 1989-11-27 | 1993-08-17 | Concat, Ltd. | MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands |
| US5147632A (en) * | 1990-10-31 | 1992-09-15 | Warner-Lambert Company | Anti-plaque compositions comprising a combination of morpholinoamino alcohol and chelating agent |
| BR9206910A (pt) * | 1991-12-10 | 1995-11-21 | Dow Chemical Co | Composições orais para inibição da formação de placas e cálculos |
| US5409689A (en) | 1993-08-13 | 1995-04-25 | Concat, Ltd. | MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms |
| US6525041B1 (en) * | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| FR2737204B1 (fr) * | 1995-07-26 | 1997-09-12 | Oreal | Derives de n,n'-di(aralkyl)n,n'-di(carboxylakyl)alkylene di- ou triamine et de n-(aralkyl)n'-(carboxyalkyl) n,n'-di(carboxyalkyl)alkylene di- ou triamine et leur utilisation en pharmacie et en cosmetique |
| FR2749845B1 (fr) * | 1996-06-18 | 1998-08-21 | Oreal | Nouveaux derives benzyl substitue(s) de polyalkylene-polyamines et leur utilisation dans des compositions cosmetiques et pharmaceutiques |
| US6165966A (en) * | 1996-09-24 | 2000-12-26 | The Procter & Gamble Company | Liquid detergents containing proteolytic enzyme and protease inhibitors |
| GB0001129D0 (en) * | 2000-01-18 | 2000-03-08 | Unilever Plc | Anti-microbial aerosol compositions |
| EP1248591B1 (en) * | 2000-01-18 | 2007-08-08 | Unilever Plc | Anti-microbial compositions comprising a salt of a transition metal chelator |
| US6264966B1 (en) * | 2000-02-22 | 2001-07-24 | Concat, Ltd. | Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury |
-
2000
- 2000-02-22 US US09/510,134 patent/US6264966B1/en not_active Expired - Fee Related
-
2001
- 2001-02-14 EP EP08162900A patent/EP2011501A1/en not_active Withdrawn
- 2001-02-14 JP JP2001561327A patent/JP2003523394A/ja active Pending
- 2001-02-14 DE DE60135638T patent/DE60135638D1/de not_active Expired - Lifetime
- 2001-02-14 IL IL15103101A patent/IL151031A0/xx unknown
- 2001-02-14 AU AU2001237038A patent/AU2001237038A1/en not_active Abandoned
- 2001-02-14 WO PCT/US2001/004977 patent/WO2001062262A1/en not_active Ceased
- 2001-02-14 ES ES01909263T patent/ES2239924T1/es active Pending
- 2001-02-14 AT AT01909263T patent/ATE406902T1/de not_active IP Right Cessation
- 2001-02-14 DE DE0001261349T patent/DE01909263T1/de active Pending
- 2001-02-14 EP EP01909263A patent/EP1261349B1/en not_active Expired - Lifetime
- 2001-02-14 CA CA002399299A patent/CA2399299C/en not_active Expired - Fee Related
- 2001-04-20 US US09/839,970 patent/US6387891B2/en not_active Expired - Fee Related
-
2002
- 2002-08-01 IL IL151031A patent/IL151031A/en not_active IP Right Cessation
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