DD299178A5 - 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel - Google Patents

24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel Download PDF

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Publication number
DD299178A5
DD299178A5 DD90344338A DD34433890A DD299178A5 DD 299178 A5 DD299178 A5 DD 299178A5 DD 90344338 A DD90344338 A DD 90344338A DD 34433890 A DD34433890 A DD 34433890A DD 299178 A5 DD299178 A5 DD 299178A5
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DD
German Democratic Republic
Prior art keywords
homo
vitamin
compound
group
triol
Prior art date
Application number
DD90344338A
Other languages
German (de)
English (en)
Inventor
Gerald Dr Kirsch
Guenter Dr Neef
Katica Schwarz
Matthias Dr Braeutigam
Ruth Dr Thieroff-Eckerdt
Petra Rach
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Application filed by �������@������������@��k�� filed Critical �������@������������@��k��
Publication of DD299178A5 publication Critical patent/DD299178A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DD90344338A 1989-10-02 1990-10-01 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel DD299178A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3933034A DE3933034A1 (de) 1989-10-02 1989-10-02 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DD299178A5 true DD299178A5 (de) 1992-04-02

Family

ID=6390762

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90344338A DD299178A5 (de) 1989-10-02 1990-10-01 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel

Country Status (18)

Country Link
US (1) US5665716A (fi)
EP (1) EP0421561B1 (fi)
JP (1) JPH03246273A (fi)
CN (2) CN1031705C (fi)
AT (1) ATE103893T1 (fi)
AU (1) AU639717B2 (fi)
CA (1) CA2026671C (fi)
DD (1) DD299178A5 (fi)
DE (2) DE3933034A1 (fi)
DK (1) DK0421561T3 (fi)
ES (1) ES2052166T3 (fi)
FI (1) FI93643C (fi)
HU (1) HU210032B (fi)
IE (1) IE71227B1 (fi)
IL (1) IL95872A (fi)
NO (1) NO178923C (fi)
PT (1) PT95473B (fi)
ZA (1) ZA907876B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) * 1992-01-10 1997-02-06 Schering Ag (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
WO2002006218A2 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. STABILIZED 1α-HYDROXY VITAMIN D
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
CN1639329A (zh) * 2002-01-10 2005-07-13 特瓦制药工业有限公司 差向异构的维生素d类似物的选择性酶促酯化和溶剂解以及所述差向异构体的分离
EP1461314A1 (en) * 2002-06-13 2004-09-29 Teva Pharmaceutical Industries Limited Epimerization of analogs of vitamin d
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
MX2009002337A (es) * 2006-08-29 2009-03-20 Teva Pharma Composiciones farmacologicamente estables que incluyen compuestos que contienen vitamina d y corticosteroides con compatibilidad con bajo ph.
WO2009153782A1 (en) 2008-06-17 2009-12-23 Ben Gurion University Of The Negev R&D Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
EA201691980A1 (ru) 2009-01-27 2017-07-31 БЕРГ ЭлЭлСи Способы уменьшения побочных эффектов, связанных с химиотерапией
SG178382A1 (en) 2009-08-14 2012-04-27 Berg Biosystems Llc Vitamin d3 and analogs thereof for treating alopecia
CN105492081A (zh) 2013-05-29 2016-04-13 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
US10548908B2 (en) * 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582789B2 (en) * 1984-10-04 1989-04-13 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
US4832875A (en) * 1985-11-21 1989-05-23 Taisho Pharmaceutical Co., Ltd. Vitamin D3 derivative
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Also Published As

Publication number Publication date
ATE103893T1 (de) 1994-04-15
NO178923B (no) 1996-03-25
DE3933034A1 (de) 1991-04-11
JPH03246273A (ja) 1991-11-01
NO178923C (no) 1996-07-03
HU906284D0 (en) 1991-03-28
US5665716A (en) 1997-09-09
FI93643B (fi) 1995-01-31
IL95872A (en) 1995-03-15
PT95473B (pt) 1997-07-31
IE71227B1 (en) 1997-02-12
EP0421561B1 (de) 1994-04-06
DE59005254D1 (de) 1994-05-11
HU210032B (en) 1995-01-30
ES2052166T3 (es) 1994-07-01
NO904269L (no) 1991-04-03
EP0421561A2 (de) 1991-04-10
CN1053103C (zh) 2000-06-07
NO904269D0 (no) 1990-10-01
HUT55751A (en) 1991-06-28
DK0421561T3 (da) 1994-07-25
CA2026671A1 (en) 1991-04-03
CN1051907A (zh) 1991-06-05
EP0421561A3 (en) 1991-06-12
FI904850A0 (fi) 1990-10-02
AU639717B2 (en) 1993-08-05
ZA907876B (en) 1992-04-29
CN1106666A (zh) 1995-08-16
IE903520A1 (en) 1991-04-10
IL95872A0 (en) 1991-07-18
CA2026671C (en) 1998-12-08
AU6371590A (en) 1991-04-11
CN1031705C (zh) 1996-05-01
PT95473A (pt) 1991-06-25
FI93643C (fi) 1995-05-10

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