DD298478A5 - Verwendung eines heteroaryl-3-oxo-propannitrilderivats und pharmazeutisches praeparat zur behandlung von auroimmunerkrankungen - Google Patents

Verwendung eines heteroaryl-3-oxo-propannitrilderivats und pharmazeutisches praeparat zur behandlung von auroimmunerkrankungen Download PDF

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Publication number
DD298478A5
DD298478A5 DD90344383A DD34438390A DD298478A5 DD 298478 A5 DD298478 A5 DD 298478A5 DD 90344383 A DD90344383 A DD 90344383A DD 34438390 A DD34438390 A DD 34438390A DD 298478 A5 DD298478 A5 DD 298478A5
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DD
German Democratic Republic
Prior art keywords
phenyl
group
alkyl
oxo
cyano
Prior art date
Application number
DD90344383A
Other languages
German (de)
English (en)
Inventor
Gianfederico Doria
Anna M Isetta
Rinaldo Ferreccio
Mario Ferrari
Maria C Fornasiero
Domenico Trizio
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ����������@�����@����@�K�K�Kk�� filed Critical ����������@�����@����@�K�K�Kk��
Publication of DD298478A5 publication Critical patent/DD298478A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD90344383A 1989-04-06 1990-10-02 Verwendung eines heteroaryl-3-oxo-propannitrilderivats und pharmazeutisches praeparat zur behandlung von auroimmunerkrankungen DD298478A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898907799A GB8907799D0 (en) 1989-04-06 1989-04-06 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases

Publications (1)

Publication Number Publication Date
DD298478A5 true DD298478A5 (de) 1992-02-27

Family

ID=10654581

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90344383A DD298478A5 (de) 1989-04-06 1990-10-02 Verwendung eines heteroaryl-3-oxo-propannitrilderivats und pharmazeutisches praeparat zur behandlung von auroimmunerkrankungen

Country Status (15)

Country Link
US (2) US5196445A (ja)
EP (1) EP0423269B1 (ja)
JP (1) JPH03505332A (ja)
KR (1) KR920700031A (ja)
AT (1) ATE99934T1 (ja)
AU (1) AU5416990A (ja)
CA (1) CA2030530A1 (ja)
DD (1) DD298478A5 (ja)
DE (1) DE69005974T2 (ja)
GB (1) GB8907799D0 (ja)
HU (1) HUT58518A (ja)
IL (1) IL93989A0 (ja)
PT (1) PT93680A (ja)
WO (1) WO1990011760A1 (ja)
ZA (1) ZA902649B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT695547E (pt) * 1993-04-09 2001-12-28 Toyama Chemical Co Ltd Imunomodulador inibidor da adesao celular e agente para tratamento e prevencao de doencas auto-imunes
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
DE69624925T2 (de) * 1995-08-15 2003-09-04 Connetics Corp., Palo Alto Verwendung von relaxin zur stimulierung der angiogenese
US7285422B1 (en) * 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
US5902825A (en) * 1997-01-07 1999-05-11 Mitreoak, Ltd. Composition and method for the palliation of pain associated with diseases of the bone and bone joints
GB9720901D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed benzothiopyranic compounds
US20030224071A1 (en) * 1999-08-20 2003-12-04 Howard Murad Pharmaceutical compositions and methods for managing connective tissue ailments
US20030003051A1 (en) * 2001-06-11 2003-01-02 Inverardi Luca A. Methods of achieving transplantation tolerance through radioablation of hemolymphopoietic cell populations
CA2460939C (en) * 2001-09-19 2008-07-29 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
CA2460942A1 (en) * 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
US20050116027A1 (en) * 2003-06-12 2005-06-02 First Data Corp. Personalized presentation instrument production systems and methods
KR20130049766A (ko) * 2009-11-13 2013-05-14 메르크 세로노 에스. 에이. 트리사이클릭 피라졸 아민 유도체

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4173634A (en) * 1979-02-23 1979-11-06 E. R. Squibb & Sons, Inc. Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents
JPS57109787A (en) * 1980-12-26 1982-07-08 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
US4853405A (en) * 1987-01-21 1989-08-01 Farmitalia Carlo Erba S.R.L. Condensed pyrazole derivatives, pharmaceutical compositions and use
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
PH26314A (en) * 1988-08-09 1994-04-29 Boots Co Plc Benzopyrano [4,3-c] pyrazoles derivatives
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation

Also Published As

Publication number Publication date
IL93989A0 (en) 1991-01-31
WO1990011760A1 (en) 1990-10-18
HUT58518A (en) 1992-03-30
ATE99934T1 (de) 1994-01-15
AU5416990A (en) 1990-11-05
JPH03505332A (ja) 1991-11-21
EP0423269A1 (en) 1991-04-24
DE69005974D1 (de) 1994-02-24
KR920700031A (ko) 1992-02-19
PT93680A (pt) 1990-11-20
US5196445A (en) 1993-03-23
CA2030530A1 (en) 1990-10-07
GB8907799D0 (en) 1989-05-17
HU903690D0 (en) 1991-03-28
EP0423269B1 (en) 1994-01-12
US5352676A (en) 1994-10-04
ZA902649B (en) 1991-01-30
DE69005974T2 (de) 1994-05-05

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Legal Events

Date Code Title Description
WP12 As result of examination under paragraph 12 erstrg. patent revoked