ZA902649B - Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases - Google Patents

Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases

Info

Publication number
ZA902649B
ZA902649B ZA902649A ZA902649A ZA902649B ZA 902649 B ZA902649 B ZA 902649B ZA 902649 A ZA902649 A ZA 902649A ZA 902649 A ZA902649 A ZA 902649A ZA 902649 B ZA902649 B ZA 902649B
Authority
ZA
South Africa
Prior art keywords
rheumatoid arthritis
heteroaryl
oxo
treatment
autoimmune diseases
Prior art date
Application number
ZA902649A
Other languages
English (en)
Inventor
Gianfederico Doria
Doria Gianfederico
Anna Maria Isetta
Maria Isetta Anna
Rinaldo Ferreccio
Ferreccio Rinaldo
Mario Ferrari
Ferrari Mario
Maria Chiara Fomasiero
Chiara Fomasiero Maria
Domenico Trizio
Trizio Domenico
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA902649B publication Critical patent/ZA902649B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA902649A 1989-04-06 1990-04-05 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases ZA902649B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898907799A GB8907799D0 (en) 1989-04-06 1989-04-06 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases

Publications (1)

Publication Number Publication Date
ZA902649B true ZA902649B (en) 1991-01-30

Family

ID=10654581

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902649A ZA902649B (en) 1989-04-06 1990-04-05 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases

Country Status (15)

Country Link
US (2) US5196445A (ja)
EP (1) EP0423269B1 (ja)
JP (1) JPH03505332A (ja)
KR (1) KR920700031A (ja)
AT (1) ATE99934T1 (ja)
AU (1) AU5416990A (ja)
CA (1) CA2030530A1 (ja)
DD (1) DD298478A5 (ja)
DE (1) DE69005974T2 (ja)
GB (1) GB8907799D0 (ja)
HU (1) HUT58518A (ja)
IL (1) IL93989A0 (ja)
PT (1) PT93680A (ja)
WO (1) WO1990011760A1 (ja)
ZA (1) ZA902649B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2160626T3 (es) * 1993-04-09 2001-11-16 Toyama Chemical Co Ltd Inmunomodulador, inhibidor de la adherencia celular, y agente que permite tratar y prevenir enfermedades autoinmunes.
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
US6211147B1 (en) * 1995-08-15 2001-04-03 Connetics Corporation Method of promoting angiogenesis using relaxin
US7285422B1 (en) * 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
US5902825A (en) * 1997-01-07 1999-05-11 Mitreoak, Ltd. Composition and method for the palliation of pain associated with diseases of the bone and bone joints
GB9720901D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed benzothiopyranic compounds
US20030224071A1 (en) * 1999-08-20 2003-12-04 Howard Murad Pharmaceutical compositions and methods for managing connective tissue ailments
CA2449941A1 (en) * 2001-06-11 2002-12-19 University Of Miami Use of radiopharmaceutical complexes in achieving transplantation tolerance
WO2003024936A1 (en) * 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolo compounds for the treatment of inflammation
CA2460942A1 (en) * 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
US20050116027A1 (en) * 2003-06-12 2005-06-02 First Data Corp. Personalized presentation instrument production systems and methods
CN102695710B (zh) * 2009-11-13 2015-08-19 默克雪兰诺有限公司 三环吡唑胺衍生物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4173634A (en) * 1979-02-23 1979-11-06 E. R. Squibb & Sons, Inc. Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents
JPS57109787A (en) * 1980-12-26 1982-07-08 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
US4853405A (en) * 1987-01-21 1989-08-01 Farmitalia Carlo Erba S.R.L. Condensed pyrazole derivatives, pharmaceutical compositions and use
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
PH26314A (en) * 1988-08-09 1994-04-29 Boots Co Plc Benzopyrano [4,3-c] pyrazoles derivatives
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation

Also Published As

Publication number Publication date
DE69005974T2 (de) 1994-05-05
CA2030530A1 (en) 1990-10-07
HU903690D0 (en) 1991-03-28
PT93680A (pt) 1990-11-20
GB8907799D0 (en) 1989-05-17
KR920700031A (ko) 1992-02-19
ATE99934T1 (de) 1994-01-15
HUT58518A (en) 1992-03-30
DD298478A5 (de) 1992-02-27
US5352676A (en) 1994-10-04
DE69005974D1 (de) 1994-02-24
EP0423269B1 (en) 1994-01-12
JPH03505332A (ja) 1991-11-21
AU5416990A (en) 1990-11-05
WO1990011760A1 (en) 1990-10-18
EP0423269A1 (en) 1991-04-24
IL93989A0 (en) 1991-01-31
US5196445A (en) 1993-03-23

Similar Documents

Publication Publication Date Title
ZA847550B (en) Anticonvulsant sulfamate derivatives
IL64905A (en) Process for the preparation of 2-penems,carbapenems,carbacephams,oxapenems,and azapenems,some novel such compounds and pharmaceutical compositions containing them
MY132056A (en) Methods of inhibiting physiological conditions associated with an excess of neuropeptide y.
ES8606336A1 (es) Un procedimiento para la preparacion de derivados de tiazol 2,4-disustituidos
GB8907799D0 (en) Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
IE831762L (en) Xanthine derivatives
ES8605507A1 (es) Un compuesto de 3-indolcarboxamida
DK562488D0 (da) Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater
UA37311C2 (uk) Засіб для лікування статевої дисфункції і фармацевтичний препарат
PH24309A (en) Cycloalkylamides of(8beta)-1-alkyl-6-(substituted)-ergolines and pharmaceutical formulations thereof
EP0107733A4 (en) CYCLOALIPHATIC MEDICINE COMPOSITIONS.
PL295932A1 (en) Method of obtaining novel bezazepine compounds
ES8606880A1 (es) Un procedimiento para la preparacion de nuevos peptidos.
ES8303316A1 (es) Un procedimiento para la fabricacion de un disulfuro intra ointermolecular
DE3162053D1 (en) N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them
MY103293A (en) N-imidazolyl derivatives of bicyclic compounds useful in medicine
NZ332687A (en) use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
DE3374005D1 (en) 1-methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle
TW225989B (ja)
IL112110A0 (en) Octahydro-1h-isoindoles and pharmaceutical compositions containing them
HUT59595A (en) Process for producing antidepressant and antistress pharmaceutical compositons containing phenyl-ethanol-amino-tetralines
ES2009283A6 (es) Procedimiento para preparar nuevos aminoacilatos de glicerol-acetal.
MY108455A (en) Therapeutic benzazapine compounds.
ES2005778A6 (es) Procedimiento para la obtencion de derivados de diisobutilxantina.
IL116557A0 (en) Antiherpes peptidomimetic compounds their preparation and pharmaceutical compositions containing them