DE69005974D1 - Heteroaryl-3-oxo-propannitril-derivate, nützlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten. - Google Patents

Heteroaryl-3-oxo-propannitril-derivate, nützlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten.

Info

Publication number
DE69005974D1
DE69005974D1 DE90905498T DE69005974T DE69005974D1 DE 69005974 D1 DE69005974 D1 DE 69005974D1 DE 90905498 T DE90905498 T DE 90905498T DE 69005974 T DE69005974 T DE 69005974T DE 69005974 D1 DE69005974 D1 DE 69005974D1
Authority
DE
Germany
Prior art keywords
rheumatoid arthritis
treating rheumatoid
propannitrile
heteroaryl
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90905498T
Other languages
English (en)
Other versions
DE69005974T2 (de
Inventor
Gianfederico Doria
Anna Isetta
Rinaldo Ferreccio
Mario Ferrari
Maria Fornasiero
Domenico Trizio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of DE69005974D1 publication Critical patent/DE69005974D1/de
Application granted granted Critical
Publication of DE69005974T2 publication Critical patent/DE69005974T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
DE90905498T 1989-04-06 1990-04-04 Heteroaryl-3-oxo-propannitril-derivate, nützlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten. Expired - Fee Related DE69005974T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898907799A GB8907799D0 (en) 1989-04-06 1989-04-06 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
PCT/EP1990/000527 WO1990011760A1 (en) 1989-04-06 1990-04-04 Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases

Publications (2)

Publication Number Publication Date
DE69005974D1 true DE69005974D1 (de) 1994-02-24
DE69005974T2 DE69005974T2 (de) 1994-05-05

Family

ID=10654581

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90905498T Expired - Fee Related DE69005974T2 (de) 1989-04-06 1990-04-04 Heteroaryl-3-oxo-propannitril-derivate, nützlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten.

Country Status (15)

Country Link
US (2) US5196445A (de)
EP (1) EP0423269B1 (de)
JP (1) JPH03505332A (de)
KR (1) KR920700031A (de)
AT (1) ATE99934T1 (de)
AU (1) AU5416990A (de)
CA (1) CA2030530A1 (de)
DD (1) DD298478A5 (de)
DE (1) DE69005974T2 (de)
GB (1) GB8907799D0 (de)
HU (1) HUT58518A (de)
IL (1) IL93989A0 (de)
PT (1) PT93680A (de)
WO (1) WO1990011760A1 (de)
ZA (1) ZA902649B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922755A (en) * 1993-04-09 1999-07-13 Toyama Chemical Co., Ltd. Immunomodulator, cell adhesion inhibtor, and agent for treating, and preventing autoimmune diseases
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
ATE228004T1 (de) * 1995-08-15 2002-12-15 Connetics Corp Verwendung von relaxin zur stimulierung der angiogenese
US7285422B1 (en) * 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
US5902825A (en) * 1997-01-07 1999-05-11 Mitreoak, Ltd. Composition and method for the palliation of pain associated with diseases of the bone and bone joints
GB9720901D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed benzothiopyranic compounds
US20030224071A1 (en) * 1999-08-20 2003-12-04 Howard Murad Pharmaceutical compositions and methods for managing connective tissue ailments
CA2449941A1 (en) * 2001-06-11 2002-12-19 University Of Miami Use of radiopharmaceutical complexes in achieving transplantation tolerance
WO2003024935A2 (en) * 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
CA2460939C (en) * 2001-09-19 2008-07-29 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
US20050116027A1 (en) * 2003-06-12 2005-06-02 First Data Corp. Personalized presentation instrument production systems and methods
US9073940B2 (en) * 2009-11-13 2015-07-07 Merck Serono Sa Tricyclic pyrazol amine derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4173634A (en) * 1979-02-23 1979-11-06 E. R. Squibb & Sons, Inc. Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents
JPS57109787A (en) * 1980-12-26 1982-07-08 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
NZ223204A (en) * 1987-01-21 1989-12-21 Erba Farmitalia Pyrazole derivatives and pharmaceutical compositions
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
ZA895646B (en) * 1988-08-09 1990-04-25 Boots Co Plc Therapeutic agents
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation

Also Published As

Publication number Publication date
EP0423269B1 (de) 1994-01-12
US5352676A (en) 1994-10-04
EP0423269A1 (de) 1991-04-24
ZA902649B (en) 1991-01-30
GB8907799D0 (en) 1989-05-17
ATE99934T1 (de) 1994-01-15
HU903690D0 (en) 1991-03-28
IL93989A0 (en) 1991-01-31
WO1990011760A1 (en) 1990-10-18
HUT58518A (en) 1992-03-30
US5196445A (en) 1993-03-23
KR920700031A (ko) 1992-02-19
JPH03505332A (ja) 1991-11-21
DE69005974T2 (de) 1994-05-05
PT93680A (pt) 1990-11-20
DD298478A5 (de) 1992-02-27
CA2030530A1 (en) 1990-10-07
AU5416990A (en) 1990-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee