DE69009717T2 - Heteroaryl-3-oxo-propan-nitril-derivat verwendbar in erregung von myelopoiesis. - Google Patents

Heteroaryl-3-oxo-propan-nitril-derivat verwendbar in erregung von myelopoiesis.

Info

Publication number
DE69009717T2
DE69009717T2 DE69009717T DE69009717T DE69009717T2 DE 69009717 T2 DE69009717 T2 DE 69009717T2 DE 69009717 T DE69009717 T DE 69009717T DE 69009717 T DE69009717 T DE 69009717T DE 69009717 T2 DE69009717 T2 DE 69009717T2
Authority
DE
Germany
Prior art keywords
pct
heteroaryl
oxo
myelopoiesis
propane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69009717T
Other languages
English (en)
Other versions
DE69009717D1 (de
Inventor
Gianfederico Doria
Anna Isetta
Rinaldo Ferreccio
Mario Ferrari
Maria Fornasiero
Domenico Trizio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE69009717D1 publication Critical patent/DE69009717D1/de
Publication of DE69009717T2 publication Critical patent/DE69009717T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D25/00—Pumping installations or systems
    • F04D25/02—Units comprising pumps and their driving means
    • F04D25/08—Units comprising pumps and their driving means the working fluid being air, e.g. for ventilation
    • F04D25/10—Units comprising pumps and their driving means the working fluid being air, e.g. for ventilation the unit having provisions for automatically changing direction of output air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/60—Mounting; Assembling; Disassembling
    • F04D29/601—Mounting; Assembling; Disassembling specially adapted for elastic fluid pumps
DE69009717T 1989-07-17 1990-07-11 Heteroaryl-3-oxo-propan-nitril-derivat verwendbar in erregung von myelopoiesis. Expired - Fee Related DE69009717T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898916290A GB8916290D0 (en) 1989-07-17 1989-07-17 Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
PCT/EP1990/001129 WO1991001309A1 (en) 1989-07-17 1990-07-11 Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis

Publications (2)

Publication Number Publication Date
DE69009717D1 DE69009717D1 (de) 1994-07-14
DE69009717T2 true DE69009717T2 (de) 1994-09-29

Family

ID=10660137

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69009717T Expired - Fee Related DE69009717T2 (de) 1989-07-17 1990-07-11 Heteroaryl-3-oxo-propan-nitril-derivat verwendbar in erregung von myelopoiesis.

Country Status (17)

Country Link
US (1) US5206258A (de)
EP (1) EP0434807B1 (de)
JP (1) JPH04501267A (de)
KR (1) KR920701165A (de)
AT (1) ATE106875T1 (de)
AU (1) AU636375B2 (de)
CA (1) CA2036375A1 (de)
DE (1) DE69009717T2 (de)
DK (1) DK0434807T3 (de)
GB (1) GB8916290D0 (de)
HU (1) HU208631B (de)
IE (1) IE64936B1 (de)
IL (1) IL95044A (de)
MY (1) MY106985A (de)
PT (1) PT94713A (de)
WO (1) WO1991001309A1 (de)
ZA (1) ZA905604B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5886016A (en) * 1995-09-15 1999-03-23 G.D. Searle & Co. Benzopyranopyrazolyl derivatives for the treatment of inflammation
AU5147598A (en) * 1996-10-17 1998-05-11 Smithkline Beecham Corporation Methods for reversibly inhibiting myelopoiesis in mammalian tissue
GB9720901D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed benzothiopyranic compounds
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
US6485740B1 (en) * 2000-03-14 2002-11-26 Yutoku Pharmaceutical Ind., Co., Ltd. Transdermal methotrexate preparations
WO2003024935A2 (en) 2001-09-19 2003-03-27 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
CA2460939C (en) * 2001-09-19 2008-07-29 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
US20050014690A1 (en) * 2001-10-11 2005-01-20 Chaim Roifman Styryl acrylonitrile compounds and their use to promote myelopoiesis
US11564901B2 (en) * 2007-01-31 2023-01-31 Biosuccess Biotech Co., Ltd. Compositions and methods of use of phorbol esters
US9073940B2 (en) * 2009-11-13 2015-07-07 Merck Serono Sa Tricyclic pyrazol amine derivatives
KR101702468B1 (ko) 2015-07-27 2017-02-06 충남대학교산학협력단 암 예방 및 치료용 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3404157A (en) * 1965-02-24 1968-10-01 American Cyanamid Co Substituted pyrroloindazole compounds
US3969527A (en) * 1975-07-28 1976-07-13 E. R. Squibb & Sons, Inc. CNS active compounds
US4140755A (en) * 1976-02-13 1979-02-20 Hoffmann-La Roche Inc. Sustained release tablet formulations
JPS5615287A (en) * 1979-07-16 1981-02-14 Chugai Pharmaceut Co Ltd Pyrazoloindazole derivative and its preparation
US4420476A (en) * 1982-05-24 1983-12-13 Averst McKenna & Harrison, Inc. Benzofuro[3,2-c]pyrazol-3-amine derivatives
JPS60130521A (ja) * 1983-12-19 1985-07-12 Morishita Seiyaku Kk 抗癌剤
JPS6299361A (ja) * 1985-10-25 1987-05-08 Morishita Seiyaku Kk インデノ〔１，２−ｃ〕ピラゾ−ル誘導体
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation

Also Published As

Publication number Publication date
US5206258A (en) 1993-04-27
ZA905604B (en) 1991-05-29
AU6036090A (en) 1991-02-22
MY106985A (en) 1995-08-30
IL95044A0 (en) 1991-06-10
IL95044A (en) 1994-08-26
PT94713A (pt) 1991-03-20
CA2036375A1 (en) 1991-01-18
IE902583A1 (en) 1991-02-27
IE64936B1 (en) 1995-09-20
GB8916290D0 (en) 1989-08-31
EP0434807A1 (de) 1991-07-03
DK0434807T3 (da) 1994-07-04
JPH04501267A (ja) 1992-03-05
WO1991001309A1 (en) 1991-02-07
DE69009717D1 (de) 1994-07-14
HU208631B (en) 1993-12-28
KR920701165A (ko) 1992-08-11
HUT59310A (en) 1992-05-28
HU905486D0 (en) 1991-07-29
AU636375B2 (en) 1993-04-29
EP0434807B1 (de) 1994-06-08
ATE106875T1 (de) 1994-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee