DD281596A5 - Verfahren zur hersteung antiarrhytmischer mittel - Google Patents

Verfahren zur hersteung antiarrhytmischer mittel Download PDF

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Publication number
DD281596A5
DD281596A5 DD88316361A DD31636188A DD281596A5 DD 281596 A5 DD281596 A5 DD 281596A5 DD 88316361 A DD88316361 A DD 88316361A DD 31636188 A DD31636188 A DD 31636188A DD 281596 A5 DD281596 A5 DD 281596A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
concentrated
preparation
give
title compound
Prior art date
Application number
DD88316361A
Other languages
German (de)
English (en)
Inventor
John E Arrowsmith
Peter E Cross
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD281596A5 publication Critical patent/DD281596A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD88316361A 1987-09-05 1988-06-02 Verfahren zur hersteung antiarrhytmischer mittel DD281596A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878720910A GB8720910D0 (en) 1987-09-05 1987-09-05 Antiarrhythmic agents
CA000567186A CA1291164C (en) 1987-09-05 1988-05-19 Indane sulfonamide antiarrythmic agents

Publications (1)

Publication Number Publication Date
DD281596A5 true DD281596A5 (de) 1990-08-15

Family

ID=25671902

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88316361A DD281596A5 (de) 1987-09-05 1988-06-02 Verfahren zur hersteung antiarrhytmischer mittel

Country Status (13)

Country Link
EP (1) EP0307121B1 (el)
JP (1) JP2653850B2 (el)
AT (1) ATE73773T1 (el)
CA (2) CA1291164C (el)
DD (1) DD281596A5 (el)
DE (1) DE3869289D1 (el)
DK (1) DK488588A (el)
ES (1) ES2032972T3 (el)
FI (1) FI89909C (el)
GB (1) GB8720910D0 (el)
GR (1) GR3004627T3 (el)
IE (1) IE61505B1 (el)
PT (1) PT88406B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
CA2105666C (en) * 1991-04-17 2006-02-14 Kjell Anders Ivan Svensson New centrally acting substituted phenylazacycloalkanes
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
DE4335718A1 (de) * 1993-10-20 1995-04-27 Merck Patent Gmbh Cyclische Aminderivate
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
AU2002360561A1 (en) 2001-12-11 2003-06-23 Sepracor, Inc. 4-substituted piperidines, and methods of use thereof
GB2543296A (en) 2015-10-13 2017-04-19 Indivior Uk Ltd Dopamine D3 receptor antagonists having a morpholine moiety
WO2023079128A1 (en) * 2021-11-08 2023-05-11 F. Hoffmann-La Roche Ag Catalytic hydrogenation of aromatic nitro compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068669A1 (en) * 1981-06-20 1983-01-05 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0140359B1 (en) * 1983-11-02 1989-01-25 Beecham Group Plc Morpholine derivatives
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use

Also Published As

Publication number Publication date
FI884070A (fi) 1989-03-06
GB8720910D0 (en) 1987-10-14
DE3869289D1 (de) 1992-04-23
FI89909C (fi) 1993-12-10
JPS6471856A (en) 1989-03-16
DK488588A (da) 1989-03-06
ES2032972T3 (es) 1993-03-01
JP2653850B2 (ja) 1997-09-17
PT88406B (pt) 1992-10-30
CA1291164C (en) 1991-10-22
EP0307121A1 (en) 1989-03-15
IE882665L (en) 1989-03-05
DK488588D0 (da) 1988-09-02
IE61505B1 (en) 1994-11-02
PT88406A (pt) 1989-07-31
ATE73773T1 (de) 1992-04-15
FI89909B (fi) 1993-08-31
FI884070A0 (fi) 1988-09-02
EP0307121B1 (en) 1992-03-18
CA1320726C (en) 1993-07-27
GR3004627T3 (el) 1993-04-28

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