ES2032972T3 - Agentes antiarritmicos a base de sulfonamidas. - Google Patents

Agentes antiarritmicos a base de sulfonamidas.

Info

Publication number
ES2032972T3
ES2032972T3 ES198888307956T ES88307956T ES2032972T3 ES 2032972 T3 ES2032972 T3 ES 2032972T3 ES 198888307956 T ES198888307956 T ES 198888307956T ES 88307956 T ES88307956 T ES 88307956T ES 2032972 T3 ES2032972 T3 ES 2032972T3
Authority
ES
Spain
Prior art keywords
sulfonamides
agents based
antiarrhythmic agents
sulphonamide
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888307956T
Other languages
English (en)
Inventor
John Edmund Dr. Arrowsmith
Peter Edward Dr. Cross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of ES2032972T3 publication Critical patent/ES2032972T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION PROPORCIONA AGENTES ARRITMICOS DE SULFONAMIDA DE LA FORMULA(I) DONDE CADA R, QUE ES EL MISMO, ES UN GRUPO C1 - C4 ALQUILO; X ES CH2 O O; E Y ES O O UN ENLACE DIRECTO; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE ESTO.
ES198888307956T 1987-09-05 1988-08-26 Agentes antiarritmicos a base de sulfonamidas. Expired - Lifetime ES2032972T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878720910A GB8720910D0 (en) 1987-09-05 1987-09-05 Antiarrhythmic agents
CA000567186A CA1291164C (en) 1987-09-05 1988-05-19 Indane sulfonamide antiarrythmic agents

Publications (1)

Publication Number Publication Date
ES2032972T3 true ES2032972T3 (es) 1993-03-01

Family

ID=25671902

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888307956T Expired - Lifetime ES2032972T3 (es) 1987-09-05 1988-08-26 Agentes antiarritmicos a base de sulfonamidas.

Country Status (13)

Country Link
EP (1) EP0307121B1 (es)
JP (1) JP2653850B2 (es)
AT (1) ATE73773T1 (es)
CA (2) CA1291164C (es)
DD (1) DD281596A5 (es)
DE (1) DE3869289D1 (es)
DK (1) DK488588A (es)
ES (1) ES2032972T3 (es)
FI (1) FI89909C (es)
GB (1) GB8720910D0 (es)
GR (1) GR3004627T3 (es)
IE (1) IE61505B1 (es)
PT (1) PT88406B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
CA2105666C (en) * 1991-04-17 2006-02-14 Kjell Anders Ivan Svensson New centrally acting substituted phenylazacycloalkanes
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
DE4335718A1 (de) * 1993-10-20 1995-04-27 Merck Patent Gmbh Cyclische Aminderivate
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
AU2002360561A1 (en) 2001-12-11 2003-06-23 Sepracor, Inc. 4-substituted piperidines, and methods of use thereof
GB2543296A (en) 2015-10-13 2017-04-19 Indivior Uk Ltd Dopamine D3 receptor antagonists having a morpholine moiety
WO2023079128A1 (en) * 2021-11-08 2023-05-11 F. Hoffmann-La Roche Ag Catalytic hydrogenation of aromatic nitro compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068669A1 (en) * 1981-06-20 1983-01-05 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0140359B1 (en) * 1983-11-02 1989-01-25 Beecham Group Plc Morpholine derivatives
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use

Also Published As

Publication number Publication date
FI884070A (fi) 1989-03-06
GB8720910D0 (en) 1987-10-14
DE3869289D1 (de) 1992-04-23
FI89909C (fi) 1993-12-10
JPS6471856A (en) 1989-03-16
DK488588A (da) 1989-03-06
JP2653850B2 (ja) 1997-09-17
PT88406B (pt) 1992-10-30
CA1291164C (en) 1991-10-22
EP0307121A1 (en) 1989-03-15
IE882665L (en) 1989-03-05
DK488588D0 (da) 1988-09-02
IE61505B1 (en) 1994-11-02
DD281596A5 (de) 1990-08-15
PT88406A (pt) 1989-07-31
ATE73773T1 (de) 1992-04-15
FI89909B (fi) 1993-08-31
FI884070A0 (fi) 1988-09-02
EP0307121B1 (en) 1992-03-18
CA1320726C (en) 1993-07-27
GR3004627T3 (es) 1993-04-28

Similar Documents

Publication Publication Date Title
ES2032972T3 (es) Agentes antiarritmicos a base de sulfonamidas.
PT87051A (pt) Process for preparing indane sulphonamide antiarrhythmic agents
PT87048A (pt) Process for preparing benzazepine sulfonamides antiarrhythmic agents
DE3861155D1 (de) Antiarrhythmische mittel.
FI863701A0 (fi) Propanolderivat.
DK353785A (da) 2,5-pyrrolidindionderivater

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