DD263531A5 - Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen - Google Patents

Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen Download PDF

Info

Publication number
DD263531A5
DD263531A5 DD86308077A DD30807786A DD263531A5 DD 263531 A5 DD263531 A5 DD 263531A5 DD 86308077 A DD86308077 A DD 86308077A DD 30807786 A DD30807786 A DD 30807786A DD 263531 A5 DD263531 A5 DD 263531A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
pyrimidinyl
dione
product
compounds
Prior art date
Application number
DD86308077A
Other languages
German (de)
English (en)
Inventor
Michael G Bright
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD263531A5 publication Critical patent/DD263531A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD86308077A 1986-10-21 1986-10-19 Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen DD263531A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/002224 WO1988003024A1 (en) 1986-10-21 1986-10-21 Bridged bicyclic imides as anxiolytics and antidepressants

Publications (1)

Publication Number Publication Date
DD263531A5 true DD263531A5 (de) 1989-01-04

Family

ID=22195680

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86308077A DD263531A5 (de) 1986-10-21 1986-10-19 Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen

Country Status (26)

Country Link
EP (1) EP0268369B1 (xx)
JP (1) JPS63112581A (xx)
KR (1) KR900000565B1 (xx)
CN (1) CN1015987B (xx)
AT (1) ATE66222T1 (xx)
AU (1) AU579963B2 (xx)
DD (1) DD263531A5 (xx)
DE (1) DE3772158D1 (xx)
DK (1) DK547487A (xx)
EG (1) EG18718A (xx)
ES (1) ES2031517T3 (xx)
FI (1) FI90775C (xx)
GR (1) GR3002483T3 (xx)
HU (1) HU198203B (xx)
IE (1) IE60378B1 (xx)
IL (1) IL84206A (xx)
MX (1) MX8898A (xx)
MY (1) MY101833A (xx)
NO (1) NO882715L (xx)
NZ (1) NZ222229A (xx)
PH (1) PH23806A (xx)
PL (1) PL149172B1 (xx)
PT (1) PT85944B (xx)
WO (1) WO1988003024A1 (xx)
YU (1) YU45461B (xx)
ZA (1) ZA877863B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
WO1990002552A1 (en) * 1988-09-16 1990-03-22 Pfizer Inc. Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
SU1825501A3 (ru) * 1990-10-29 1995-12-10 И.В. Комиссаров Dl-3-[(4-[4- (2-пиридил)-1- пиперазинил]бутил)] -1,8,8-триметил -3-азабицикло[3,2,1] октан-2,4-диона дигидрохлорид, проявляющий противотревожную, нейролептическую и противорвотную активность
CN101906107B (zh) * 2010-08-02 2012-12-26 南京林业大学 一种由α-蒎烯合成樟脑酸酐的方法
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006233A (en) * 1974-10-04 1977-02-01 Merck & Co., Inc. N-(pyrimidinyl)-tricyclo[3(or 4).2.2.02,4(or 5) ]-non (or dec)ene-dicarboximides
US4173646A (en) * 1974-10-04 1979-11-06 Merck & Co., Inc. Tricyclicdicarboximides
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
PH23806A (en) 1989-11-23
EG18718A (en) 1993-12-30
DK547487A (da) 1988-04-22
ZA877863B (en) 1989-06-28
YU192087A (en) 1988-10-31
FI90775C (fi) 1994-03-25
NO882715D0 (no) 1988-06-20
PL268296A1 (en) 1988-08-18
GR3002483T3 (en) 1992-12-30
IL84206A0 (en) 1988-03-31
DE3772158D1 (de) 1991-09-19
CN87107107A (zh) 1988-05-04
HU198203B (en) 1989-08-28
KR880005120A (ko) 1988-06-28
JPS63112581A (ja) 1988-05-17
PT85944B (pt) 1990-07-31
AU579963B2 (en) 1988-12-15
NZ222229A (en) 1989-12-21
IL84206A (en) 1992-07-15
IE872835L (en) 1988-04-21
EP0268369B1 (en) 1991-08-14
FI90775B (fi) 1993-12-15
CN1015987B (zh) 1992-03-25
FI882942A0 (fi) 1988-06-20
ES2031517T3 (es) 1992-12-16
NO882715L (no) 1988-06-20
WO1988003024A1 (en) 1988-05-05
PT85944A (en) 1987-11-01
ATE66222T1 (de) 1991-08-15
AU7994687A (en) 1988-04-28
MY101833A (en) 1992-01-31
DK547487D0 (da) 1987-10-20
EP0268369A1 (en) 1988-05-25
MX8898A (es) 1993-10-01
KR900000565B1 (ko) 1990-01-31
FI882942A (fi) 1988-06-20
HUT47270A (en) 1989-02-28
IE60378B1 (en) 1994-07-13
YU45461B (en) 1992-05-28
PL149172B1 (en) 1990-01-31
JPH0448792B2 (xx) 1992-08-07

Similar Documents

Publication Publication Date Title
DE1695556C3 (de) 3-Alkyl-1,2,3,4,4a,9-hexahydropyrazino[1,2-f]morphanthridinderivate
EP0270947B1 (de) Substituierte basische 2-Aminotetraline
DE69000467T2 (de) Bis-aza-bicyclische anxiolytica und antidepressiva.
DE68910210T2 (de) (1-Hydroxy-2-piperidinylalkyl)-2-indolon, 2-quinolinon, 2-benzo[b]azepinon, 2-benzimidazolon und 2-quinazolinon-Derivate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung.
DE3433327A1 (de) 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)alkyl)piperazinderivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische mittel
DE2915318A1 (de) Cycloalkyltriazole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0156191B1 (de) Kondensierte Diazepinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1643262B2 (de) l-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DD263531A5 (de) Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen
DE1807218A1 (de) Oxotremorin-Antagonisten und Verfahren zu deren Herstellung
DD146186A5 (de) Verfahren zur herstellung einer 4a,9b-hexahydro-ypsilon-verbindung
EP0179386B1 (de) 1,4-Dihydropyridin-hydroxyamine, Verfahren zu ihrer Herstellung sowie ihre Verwendung in Arzneimitteln
CH671579A5 (xx)
DD264214A5 (de) Verfahren zur herstellung von spiroimidazolidinen
DE3626095A1 (de) Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0435902B1 (de) 2-hydroxy-3-phenoxy-propyl-substituierte piperazine, ihre herstellung und verwendung
EP0508370B1 (de) Kondensierte Diazepinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Mittel zur Behandlung von Erkrankungen des Zentralnervensystems und zur Förderung der cerebralen Durchblutung
DE3889043T2 (de) N-(substituiertes Alkyliden)-1,2,3,4-tetrahydro-9-acridinamine, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikamente.
EP0405298A1 (de) Thienopyran-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung
DE4131584A1 (de) Imidazolylmethyl-pyridine, ihre herstellung und anwendung als pharmazeutika
DE69219801T2 (de) 9-Aminotetrahydroakridinederivate und verwandte Derivate, Verfahren zur ihrer Herstellung und ihre Anwendung als Arzneimittel
DE69617001T2 (de) (2-morpholinylmethyl)benzamid-derivate
DE3503074A1 (de) Hydantoinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
DE1695228A1 (de) Verfahren zur Herstellung von aromatischen Verbindungen
DE69116302T2 (de) 4-[4- oder 6-(Trifluormethyl-2-pyridinyl)]-1-piperazinyl-alkyl substituierte Laktame

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee